A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers +10 more
wiley +1 more source
Enteropathogen antibody dynamics and force of infection among children in low-resource settings. [PDF]
Little is known about enteropathogen seroepidemiology among children in low-resource settings. We measured serological IgG responses to eight enteropathogens (Giardia intestinalis, Cryptosporidium parvum, Entamoeba histolytica, Salmonella enterica ...
Arnold, Benjamin F +12 more
core
Human infections associated with wild birds. [PDF]
IntroductionWild birds and especially migratory species can become long-distance vectors for a wide range of microorganisms. The objective of the current paper is to summarize available literature on pathogens causing human disease that have been ...
Bauchinger, Ulf +4 more
core +1 more source
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley +1 more source
Torque teno virus: an improved indicator for viral pathogens in drinking waters
Background Currently applied indicator organism systems, such as coliforms, are not fully protective of public health from enteric viruses in water sources.
Long Sharon C +2 more
doaj +1 more source
Comparative Susceptibility of Kidney Cells from Different Monkey Species to Enteric Viruses (Poliomyelitis, Coxsackie, and Echo Groups) [PDF]
G. D. Hsiung, Joseph L. Melnick
openalex +1 more source
A galactose‐modified supramolecular near‐infrared (NIR) glycoprobe, TCF‐FBN@Gal‐BSA, enables targeted delivery to the liver through the asialoglycoprotein receptor (ASGPR) and facilitates liver‐targeting fluorescence visualization of lipid droplets (LDs) in metabolic dysfunction‐associated steatotic liver disease (MASLD) mice.
Han‐Min Wang +12 more
wiley +1 more source
Late-onset enteric virus infection associated with hepatitis (EVAH) in transplanted SCID patients. [PDF]
Riller Q +57 more
europepmc +1 more source
Morphologic Characteristics of Plaques Produced on Monkey Kidney Monolayer Cultures by Enteric Viruses (Poliomyelitis, Coxsackie, and Echo Groups) [PDF]
G. D. Hsiung, Joseph L. Melnick
openalex +1 more source
Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham +9 more
wiley +1 more source

