Results 131 to 140 of about 90,716 (312)

Occurrence of Picobirnavirus in Domestic and Wild Animals from Three Cities of Brazilian Amazon

Zoonotic Diseases
This study aimed to detect picobirnavirus (PBV) in the fecal samples of wild and domestic animals from 2014 to 2016 in the Amazon biome. Fecal samples from different animals, including birds (n = 41) and mammals (n = 217), were used. The PAGE test showed
Elaine Hellen Nunes Chagas, Julia Rezende da Silva, Bruno de Cássio Veloso de Barros, José Wandilson Barbosa Duarte Júnior, Fabiolla da Silva dos Santos, Edivaldo Costa Sousa Júnior, Delana Andreza Melo Bezerra, Maria Inês dos Santos, Helder Henrique Costa Pinheiro, Yashpal Singh Malik, Joana D’Arc Pereira Mascarenhas   +10 more
doaj   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

Porcine Hemagglutinating Encephalomyelitis Virus Enters Neuro-2a Cells via Clathrin-Mediated Endocytosis in a Rab5-, Cholesterol-, and pH-Dependent Manner [PDF]

, 2017
Zi Li, Kui Zhao, Yungang Lan, Xiaoling Lv, Shiyu Hu, Jiyu Guan, Huijun Lu, Jing Zhang, Junchao Shi, Ya‐Wen Yang, Deguang Song, Feng Gao, Wenqi He   +12 more
openalex   +1 more source

3D Printing of Bacteriophage‐Loaded Hydrogels: Development of a Local and Long‐Lasting Delivery System

Advanced Healthcare Materials, EarlyView.
This research investigates the feasibility of 3D‐printing of a bacteriophage‐containing hydrogel made of alginate and methylcellulose. The printed hydrogels steadily release active bacteriophages for up to 35 days which is beneficial to treat implant‐associated infections.
Corina Vater, Gopala Krishna Mannala, Max von Witzleben, Richard Frank Richter, Nike Walter, Michael Gelinsky, Volker Alt, Anja Lode, Markus Rupp   +8 more
wiley   +1 more source

Experimental and CFD evaluation of ozone efficacy against coronavirus and enteric virus contamination on public transport surfaces. [PDF]

J Environ Chem Eng, 2021
Falcó I, Randazzo W, Sánchez G, Vilarroig J, Climent J, Chiva S, Chica A, Navarro-Laboulais J.   +7 more
europepmc   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

The Intestinal Microbiome Primes Host Innate Immunity against Enteric Virus Systemic Infection through Type I Interferon. [PDF]

mBio, 2021
Yang XL, Wang G, Xie JY, Li H, Chen SX, Liu W, Zhu SJ.   +6 more
europepmc   +1 more source

Mouse mammary tumor virus-based vector transduces non-dividing cells, enters the nucleus via a TNPO3-independent pathway and integrates in a less biased fashion than other retroviruses [PDF]

, 2014
Constantine James Konstantoulas, Stanislav Indik   +1 more
openalex   +1 more source

The phenuivirus Toscana virus makes an atypical use of vacuolar acidity to enter host cells [PDF]

, 2023
Jana Koch, Qilin Xin, Martin Obr, Alicia Schäfer, Nina Rolfs, Holda A. Anagho, Aiste Kudulyte, Lea Woltereck, Susann Kummer, Joaquín Campos, Zina M. Uckeley, Lesley Bell‐Sakyi, Hans‐Georg Kräusslich, F.K.M. Schur, Claudio Acuna, Pierre‐Yves Lozach   +15 more
openalex   +1 more source