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Enteric viruses propagated in HIOs and HIEs.
Schematic representation of HIEs and HIOs and human enteric viruses propagated in them to date. Left: HIEs derived from biopsies of intestinal crypts are grown in 3D cultures and then transformed into 2D monolayers prior to virus infection.
Christiane E. Wobus (7610555) +1 more
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Understanding the genetic dynamics of circulating Human Adenovirus (HAdV) types is pivotal for effectively managing outbreaks and devising targeted interventions.
Ananya Chatterjee +8 more
doaj +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
E. coli concentrations and enteric virus detection in public domain samples, by neighborhooda.
E. coli concentrations and enteric virus detection in public domain samples, by neighborhooda.
Pengbo Liu (6468) +12 more
core +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Immunogenic Properties of a Novel Hepatitis A Vaccine Candidate Based on a Fast-Growing Viral Strain
Background/Objectives: Hepatitis A virus (HAV) yearly causes over 150 million new infections and around 40,000 deaths. Current vaccines are based on strains that grow poorly in cell culture, leading to high production costs and limited availability. This
Maria Isabel Costafreda +11 more
doaj +1 more source
Enteric viruses in the Caliciviridae family cause acute gastroenteritis in humans and animals, but the cellular processes needed for virus replication and disease remain unknown.
Alicia C. Strtak +5 more
doaj +1 more source
Studio delle possibili interazioni tra virus di derivazione umana e protisti in ambiente idrico [PDF]
The ability of protists to host some bacterial pathogens such as Legionella, which have developed resistance mechanisms to escape phagocytosis and/or digestion by protists, it is well known, while some studies suggest that protists may have a possible ...
BATTISTINI, ROBERTA
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source

