Results 61 to 70 of about 46,669 (258)

Unveiling the enterovirus diversity in Barcelona, Spain (2020–2024) through wastewater and clinical surveillance

open access: yesEmerging Microbes and Infections
Enterovirus (EV) infections are common and often mild or asymptomatic but can occasionally cause serious illness in children. Routine clinical surveillance typically underestimates the full spectrum of circulating EVs, whereas wastewater-based ...
David Garcia-Pedemonte   +14 more
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Enteric Viral Co-Infections: Pathogenesis and Perspective

open access: yesViruses, 2020
Enteric viral co-infections, infections involving more than one virus, have been reported for a diverse group of etiological agents, including rotavirus, norovirus, astrovirus, adenovirus, and enteroviruses. These pathogens are causative agents for acute
Heyde Makimaa   +2 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Enteritis due to Feline Infectious Peritonitis Virus

open access: yesThe Japanese Journal of Veterinary Science, 1982
臨床・病理・血清学的にネコ伝染性腹膜炎(FIP)と診断され死亡したネコ4例および仔ネコの実験接種例14例について, 腸病変とウイルス抗原あるいはウイルス粒子の所在を検索した. 自然例2例および実験例12例が下痢を発した. 多くの病例の小腸・大腸粘膜は水腫性に肥厚し, 腸内容は水様~粘液状であった. 自然例3例および実験例12例の小腸・大腸病変は粘膜上皮の変性・剥離・増生を特徴とする比較的表在性の変化で, 固有層には浮腫, 少数の好中球お上び単核細胞浸潤がみられ, 隣接上皮細胞相互の癒合もしばしばみとめられた. しかし, 他の自然例1例および実験死亡例2例では, 小腸・大腸ともに炎症病変は激しく粘膜深部に及んでいた.
HAYASHI, Toshiharu   +3 more
openaire   +3 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Clinical Screening of Cytomegalovirus Infection beyond 21 Days in the Absence of its Routine Screening in Resource Limited Settings: A Cross-sectional Study

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Testing for congenital Cytomegalovirus (cCMV) infection is not part of routine care in resource-limited settings. Consequently, the diagnosis is often missed because most infections are asymptomatic and when present, symptoms are non ...
Sabbir Ansari   +7 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Advances in Diagnostic Approaches for Viral Etiologies of Diarrhea: From the Lab to the Field

open access: yesFrontiers in Microbiology, 2019
The applications of correct diagnostic approaches play a decisive role in timely containment of infectious diseases spread and mitigation of public health risks.
Yashpal Singh Malik   +16 more
doaj   +1 more source

Molecular characterization of the genome of duck enteritis virus

open access: yesVirology, 2009
The genomic sequence of a strain of duck enteritis virus (DEV) was determined and analyzed in this study. The size of its genome is 158,091 bp in length and the genome is predicted to encode 78 putative proteins and resembles the members of the Alphaherpesvirinae in genomic organization and gene composition.
Li, Yufeng   +7 more
openaire   +2 more sources

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