Results 61 to 70 of about 1,217,622 (299)

The hepatocyte traffic network in the human hepatitis A virus biological cycle from an evolutionary perspective

Communications Biology
Hepatitis A virus (HAV) egresses from hepatocytes cloaked in exosomes (eHAV). However, the traffic network used for its release from polarized hepatocytes is not completely understood. We propose that eHAV biogenesis may follow not only an ESCRT-mediated
Albert Carcereny, Alba Arrebola, Gemma Chavarria-Miró, Montserrat de Castellarnau, Cristina Fuentes, David Garcia-Pedemonte, Adán Martínez-Velázquez, Enric Ribes, Albert Bosch, Susana Guix, Maria Isabel Costafreda, Rosa M. Pintó   +11 more
doaj   +1 more source

The enteric nervous system : new developments and emerging concepts [PDF]

, 2011
The enteric nervous system (ENS) is an integrative neuronal network, organized in two ganglionated plexuses, myenteric and submucosal, composed of neurons and enteric glial cells, controlling the activity of the smooth muscle of the gut, mucosal ...
Serio, Rosa, Mastropaolo, Mariangela, Garzia Zizzo, Maria, ZIZZO, Maria Grazia, SERIO, Rosa Maria   +4 more
core  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Novel microRNAs encoded by duck enteritis virus

Journal of General Virology, 2012
Duck enteritis virus (DEV) is an important herpesvirus pathogen associated with acute, highly contagious lethal disease in waterfowls. Using a deep sequencing approach on RNA from infected chicken embryo fibroblast cultures, we identified several novel DEV-encoded micro (mi)RNAs.
Yongxiu, Yao, Lorraine P, Smith, Lawrence, Petherbridge, Mick, Watson, Venugopal, Nair   +4 more
openaire   +2 more sources

Prevention and treatment of enteric viral infections: possible benefits of probiotic bacteria.

, 2007
International audienceThe structure and function of the intestinal epithelium is briefly described, with the principal mechanisms involved in diarrhea. Human enteric viruses and probiotics are presented.
Florence Colbère-Garapin, Arnaud Autret, Alan François, Blondel, Bruno, Mousson, Laurence, Isabelle Pelletier, Ariane van de Moer, Sandra Martin-Latil, Autret, Arnaud, van de Moer, Ariane, Niborski, Violeta, Gianfranco Grompone, Colbère-Garapin, Florence, Laurence Mousson, François, Alan, Martin-Latil, Sandra, Pelletier, Isabelle, Bruno Blondel, Guillaume Catonnet, Violeta Niborski, Grompone, Gianfranco, Catonnet, Guillaume   +21 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

A Decade-Long Cohort Analysis of Human Cytomegalovirus (HCMV)-Induced Early and Late Renal Rejection in Post-Transplant Patients in the Eastern Indian Population

Viruses
Background: HCMV causes severe clinical complications in transplant recipients and may lead to graft rejection. Successful renal transplantation heavily relies on the early prevention and diagnosis of CMV infections, followed by prompt prophylactic ...
Debsopan Roy, Aroni Chatterjee, Atanu Pal, Rajendra Prasad Chatterjee, Nilanjan Chakraborty   +4 more
doaj   +1 more source

Microbiota and enteric viruses infection

Medicine in Microecology, 2020
Enteric viruses can directly infect the mammalian gastrointestinal tract which is home to a diverse community of commensal microorganism. Emerging evidence suggests that certain enteric viruses utilize these microbiotas to promote infection.
Peng-Nien Huang
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source