Results 61 to 70 of about 40,975 (295)

Molecular characterization of the duck enteritis virus US10 protein [PDF]

Virology Journal, 2017
There is little information regarding the duck enteritis virus (DEV) US10 gene and its molecular characterization.Duck enteritis virus US10 was amplified and cloned into the recombinant vector pET32a(+). The recombinant US10 protein was expressed in Escherichia coli BL21 cells and used to immunize rabbits for the preparation of polyclonal antibodies ...
Mafeng Liu, Qiao Yang, Shun Chen, Ying Wu, Mingshu Wang, Daixi Zhang, Kunfeng Sun, Maoyin Lai, Dekang Zhu, Anchun Cheng, Xiaoyue Chen, Renyong Jia, Xinxin Zhao   +12 more
openaire   +4 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Advances in Diagnostic Approaches for Viral Etiologies of Diarrhea: From the Lab to the Field

Frontiers in Microbiology, 2019
The applications of correct diagnostic approaches play a decisive role in timely containment of infectious diseases spread and mitigation of public health risks.
Yashpal Singh Malik, Atul Kumar Verma, Naveen Kumar, Nadia Touil, Kumaragurubaran Karthik, Ruchi Tiwari, Durlav Prasad Bora, Kuldeep Dhama, Souvik Ghosh, Maged Gomaa Hemida, Maged Gomaa Hemida, Ahmed S. Abdel-Moneim, Ahmed S. Abdel-Moneim, Krisztián Bányai, Anastasia N. Vlasova, Nobumichi Kobayashi, Raj Kumar Singh   +16 more
doaj   +1 more source

Molecular characterization of duck enteritis virus UL41 protein [PDF]

Virology Journal, 2018
Duck enteritis virus (DEV) belongs to the subfamily Alphaherpesvirinae, and information on the DEV UL41 gene is limited.The DEV UL41 gene was cloned into the pET32a(+) vector and expressed in a prokaryotic expression system. Antiserum was raised against a bacterially expressed UL41-His fusion protein for further experiments.
Xiaoyue Chen, Ying Wu, Dekang Zhu, Mingshu Wang, Xinxin Zhao, Tianqiong He, Mafeng Liu, Renyong Jia, Xuelian Cao, Qiao Yang, Kunfeng Sun, Shun Chen, Anchun Cheng   +12 more
openaire   +4 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Investigation of Enteric Viruses Associated With Runting and Stunting in Day-Old Chicks and Older Broilers in Southwest Nigeria

Frontiers in Veterinary Science, 2019
Enteric viruses are known to have significant economic impact on poultry, especially broiler chicken flocks, because of production losses attributable to poor feed conversion and weight gain.
Adebowale I. Adebiyi, Paula L. Tregaskis, Daniel O. Oluwayelu, Victoria J. Smyth   +3 more
doaj   +1 more source

Expression and characterization of duck enteritis virus gI gene [PDF]

Virology Journal, 2011
Abstract Background At present, alphaherpesviruses gI gene and its encoding protein have been extensively studied. It is likely that gI protein and its homolog play similar roles in virions direct cell-to-cell spread of alphaherpesviruses. But, little is known about the characteristics of DEV gI gene.
Anchun Cheng, Xiaoyuan Yang, Dekang Zhu, Renyong Jia, Mingshu Wang, Lijuan Li, Xiaoyue Chen, Qihui Luo, Jun Xiang, Yi Zhou, Zhengli Chen, Shunchuan Zhang   +11 more
openaire   +3 more sources

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Transmissible Turkey Enteritis Virus

, 1983
This chapter provides an overview of the classification, description, hosts, key developments, diagnostic techniques, and diagnostic reagents for the transmissible turkey enteritis virus. It is a highly infectious agent causing depression, diarrhea, and anorexia in all ages of turkeys, but young stocks are more severely affected.
openaire   +1 more source

Small modifier, big decision: switching to SUMO mode adds weight to cancer stemness in mammary tumors

Molecular Oncology, EarlyView.
Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley   +1 more source