Results 71 to 80 of about 113,350 (304)

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Immune response of Enterobacter aerogenes ghost vaccine in mice [PDF]

, 2023
Faten Z. Mohammed, Akaber T. Keshta, Mahmoud Ayman Hassan, Hossam Ghoneim, Amro Abd Al Fattah Amara, Salah A. Sheweita   +5 more
openalex   +1 more source

MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts

Advanced Science, EarlyView.
We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang, Yuli Zhang, Zixin Kang, Jiayun Xiong, Ronghua Yang, Kang Ning   +5 more
wiley   +1 more source

Principles for Rigorous Design and Application of Synthetic Microbial Communities

Advanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang, Minyu Jing, Lihui Lyu, Li Nie, Xihui Xu, Ru Sun, Xiyuan Xu, Siyu Chen, Shuobing He, Yumeng Zhang, Ping Huang, Weijie Luo, Jiaojiao Liang, Guifeng Gao, Kunkun Fan, Teng Yang, Liyan Zhang, Xiao Fu, Sarah M. Allard, Jack A. Gilbert, Jiabao Zhang, Haiyan Chu   +21 more
wiley   +1 more source

Decoding the microbial blueprint of pancreatic cancer

Frontiers in Medicine
Pancreatic cancer (PC) represents one of the most formidable challenges in oncology, characterized by its asymptomatic onset, delayed clinical detection, and dismal prognosis.
Jhommara Bautista, Ricardo Bedón-Galarza, Ricardo Bedón-Galarza, Francisco Martínez-Hidalgo, Martina Masache-Cruz, Melanie Benítez-Núñez, Camila Valencia-Arroyo, Andrés López-Cortés   +7 more
doaj   +1 more source

Epidemiology of extended spectrum β-lactamase producing Enterobacter bacteremia in a brazilian hospital Epidemiologia de bacteremia causadas por Enterobacter produtores de β-lactamases de espectro estendido em um hospital brasileiro

Revista da Sociedade Brasileira de Medicina Tropical, 2010
INTRODUCTION: Enterobacter can be included in the group of extended spectrum β-lactamases (EBSL)-producing bacteria, though few studies exist evaluating risk factors associated with this microorganism.
Felipe Francisco Tuon, Leila Carolina Bianchet, Sergio Ricardo Penteado-Filho   +2 more
doaj   +1 more source

Genomic Epidemiology of Global Carbapenemase-Producing Enterobacter spp., 2008–2014

Emerging Infectious Diseases, 2018
We performed whole-genome sequencing on 170 clinical carbapenemase-producing Enterobacter spp. isolates collected globally during 2008–2014. The most common carbapenemase was VIM, followed by New Delhi metallo-β-lactamase (NDM), Klebsiella pneumoniae ...
G. Peirano, Y. Matsumura, M. Adams, P. Bradford, M. Motyl, Liang Chen, B. Kreiswirth, J. Pitout   +7 more
semanticscholar   +1 more source

Nanoconfinement‐Steered Molecular Preorganization Enables Efficient Monoethanolamine Degradation through Electronically Modulated High‐Valent Iron–Oxo Pathways

Advanced Science, EarlyView.
Precise modulation of reaction pathways remains an unresolved challenge in peroxymonosulfate‐activated advanced oxidation processes. The spatial preorganization strategy in engineered confinement architecture enables regioselective bond cleavage in monoethanolamine via synergistic proton–electron transfer, redirecting its degradation from nonselective ...
Lin Zhang, Qin Dai, Xinyue Chen, Hang Yuan, Lei Xing, Zhimo Fang, Xiuze Li, Xiangke Wang, Lihui Zhang, Junping Zhao, Qiangwei Li, Lidong Wang   +11 more
wiley   +1 more source

Extended-Spectrum β-lactamase Production among Enterobacter cloacae and Enterobacter aerogenes at a Tertiary Care Center in Coastal Karnataka [PDF]

National Journal of Laboratory Medicine, 2016
Introduction: Enterobacter spp. have been increasingly isolated as nosocomial pathogens. Multi-drug resistance is more frequently noted among these pathogens. Extended spectrum beta lactamases (ESBLs) are difficult to detect in Enterobacter spp.
Shashidhar Vishwanath, Swetha PS, Sushma M, Indira Bairy, Chiranjay Mukhopadhyay   +4 more
doaj   +1 more source

Enhanced biohydrogen production from cotton stalk hydrolysate of Enterobacter cloacae WL1318 by overexpression of the formate hydrogen lyase activator gene

Biotechnology for Biofuels, 2020
Biohydrogen production from lignocellulose has become an important hydrogen production method due to its diversity, renewability, and cheapness. Overexpression of the formate hydrogen lyase activator (fhlA) gene is a promising tactic for enhancement of ...
Qin Zhang, Shaolin You, Yanbin Li, Xiaowei Qu, Hui Jiang   +4 more
semanticscholar   +1 more source