Results 81 to 90 of about 182,351 (364)

The Multitarget Compound ZLY032 Achieves Treatment of Chronic Wounds

Advanced Science, EarlyView.
ZLY032, a dual free fatty acid receptor 1/peroxisome proliferator‐activated receptor δ agonist, accelerates wound healing in normal/diabetic/methicillin‐resistant Staphylococcus aureus‐infected models by promoting angiogenesis, reducing inflammation, and exhibiting antibacterial activity via argininosuccinate lyase targeting, with demonstrated efficacy
Manyu Gong, Zhiyuan Du, Tiantian Gong, Yu Wang, Chenchen Yin, Bosi Sun, Zijia Liu, Lianru Chen, Zibin Liao, Wenxin Wang, Tianjiao Zhao, Yifei Wang, Ying Dong, Kexin Wang, Mengru Ma, Weijun Li, Jiacheng Li, Haodong Li, Congcong Lin, Ying Zhang, Yu Liu, Xin Liu, Tao Ban, Hongxia Bao, Ying Zhang, Yang Zhang, Zheng Li, Lei Jiao   +27 more
wiley   +1 more source

Biological control and biomass evaluation of Botrytis cinerea : a thesis presented in partial fulfilment of the requirements for the degree of Master of Applied Science at Massey University [PDF]

, 1998
The efficacy of biocontrol agents is often judged by symptom development on inoculated plants. This process can involve long delays, as with Botrytis infection of kiwifruit and an alternative, quicker approach would be useful.
Vingnanasingam, Vallipuram
core  

A Novel nor@DHB Matrix for Direct Microbial Analysis in Lung Cancer Tissues

Advanced Science, EarlyView.
Integrated matrix‐assisted laser desorption/ionization mass spectrometry workflow quantifies intratumoral microbes in lung cancer through lipopolysaccharide/lipid A extraction from biopsies. The novel ionic matrix called norharmane conjugated to 2,5‐dihydroxybenzoic acid enhances lipid A ionization, enabling direct detection of bacterial genera ...
Liang Shan, Xin Xu, Lin Huang, Dan Li, Yiran Deng, Xiangfei Xue, Susu Guo, Yiman Huang, Xiao Zhang, Yongchun Yu, Lifang Ma, Kun Qian, Jiayi Wang   +12 more
wiley   +1 more source

Antibiotic Resistance Profile, Outer Membrane Proteins, Virulence Factors and Genome Sequence Analysis Reveal Clinical Isolates of Enterobacter Are Potential Pathogens Compared to Environmental Isolates

Frontiers in Cellular and Infection Microbiology, 2020
Outer membrane proteins (OMPs) of gram-negative bacteria play an important role in mediating antibacterial resistance, bacterial virulence and thus affect pathogenic ability of the bacteria.
M. Mishra, S. Panda, Susmita Barik, Arup Sarkar, D. Singh, Harapriya Mohapatra   +5 more
semanticscholar   +1 more source

Capsular profiling of the Cronobacter genus and the association of specific Cronobacter sakazakii and C. malonaticus capsule types with neonatal meningitis and necrotizing enterocolitis [PDF]

, 2015
Background: Cronobacter sakazakii and C. malonaticus can cause serious diseases especially in infants where they are associated with rare but fatal neonatal infections such as meningitis and necrotising enterocolitis.
A Lehner, A Muller, A Rahman, AS Shashkov, C Iversen, C Iversen, C Whitfield, DL Daniels, E Hurrell, E Hurrell, E Jackson, E Kucerova, E Kucerova, EE Jackson, F Ramos-Morales, GI Dancer, H Kim, H Sonbol, J Caubilla-Barron, J Caubilla-Barron, J Kajimura, JR Mehall, K Butela, KA Jolley, KA Power, KG Jarvis, KG Jarvis, LL MacLean, LL MacLean, LM Willis, LS Harris, M Blažková, M Czerwicka, M Hobbs, M Scheepe-Leberkühne, MW Gilmour, N Mullane, N Navasa, NP Arbatsky, O Holy, O Holy, P. Ogrodzki, PN Danese, S Hariri, S Joseph, S Joseph, S Joseph, S Joseph, S Joseph, S Kumar, S. Forsythe, SJ Forsythe, SM Townsend, SM Townsend, T Carver, X Zogaj, Y Sun, Y Sun   +57 more
core   +2 more sources

Prolonged Prophylactic Antibiotics Based on Preoperative Bile Culture Reduce Surgical Site Infections After Pancreaticoduodenectomy Following Preoperative Biliary Drainage: A Propensity‐Matched Analysis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Objective The optimum duration of prophylactic antibiotics after pancreaticoduodenectomy following preoperative biliary drainage to prevent surgical site infections remains controversial. We evaluate whether a prolonged course of prophylactic antibiotics reduces surgical site infection after pancreaticoduodenectomy following biliary drainage ...
Kyohei Matsumoto, Atsushi Shimizu, Yuji Kitahata, Akihiro Takeuchi, Hideki Motobayashi, Masatoshi Sato, Tomohiro Yoshimura, Shinya Hayami, Atsushi Miyamoto, Manabu Kawai   +9 more
wiley   +1 more source

Genomic Epidemiology of Global Carbapenemase-Producing Enterobacter spp., 2008–2014

Emerging Infectious Diseases, 2018
We performed whole-genome sequencing on 170 clinical carbapenemase-producing Enterobacter spp. isolates collected globally during 2008–2014. The most common carbapenemase was VIM, followed by New Delhi metallo-β-lactamase (NDM), Klebsiella pneumoniae ...
G. Peirano, Y. Matsumura, M. Adams, P. Bradford, M. Motyl, Liang Chen, B. Kreiswirth, J. Pitout   +7 more
semanticscholar   +1 more source

Polyvinyl Alcohol‐Based Cryogels: Design, Characterization, and In Vitro Biological Studies

Journal of Applied Polymer Science, EarlyView.
ABSTRACT Using inappropriate wound dressings makes the wound prone to bacteria invasion, impeding the wound‐healing process. In this work, cryogels were prepared from selected polymers, such as polyvinyl alcohol (PVA), hydroxypropylmethylcellulose (HPMC), and sodium alginate (SA) via a freeze–thaw method and loaded with Capparis sepiaria plant extract ...
Hlalisa Kula, Shirley Motaung, Mapula Razwinani, Samson A. Adeyemi, Philemon Ubanako, Lindokuhle M. Ngema, T. Y. Fonkui, D. T. Ndinteh, Pradeep Kumar, Yahya E. Choonara, Blessing A. Aderibigbe   +10 more
wiley   +1 more source

Human neutrophil clearance of bacterial pathogens triggers anti-microbial gamma delta T cell responses in early infection [PDF]

, 2011
Human blood Vc9/Vd2 T cells, monocytes and neutrophils share a responsiveness toward inflammatory chemokines and are rapidly recruited to sites of infection.
A Boëdec, A Matsushima, A Reichenberg, AC Brown, AC Hayday, AC Hayday, Amanda C. Brown, B Altincicek, B Moser, Bernhard Moser, C Agrati, C Belmant, C De Santo, C Münz, CC Szeto, Chan-Yu Lin, CM Bunke, Colin Hill, Cormac G. M. Gahan, CT Morita, CT Spencer, CT Weaver, D Vermijlen, David W. Johnson, DI Godfrey, DJ Pennington, DK Kim, E Oldfield, E. John Wherry, F Annunziato, F Dieli, F Sallusto, G Sarikonda, Gareth W. Roberts, GW Roberts, H Jomaa, H Jomaa, H Li, H Wang, H Wei, I Müller, J Feurle, J Mookerjee-Basu, James A. Chess, JF Bukowski, JJ O'Shea, John D. Williams, JS Savill, K Pietschmann, KJ Puan, KK Kumarasamy, KM Murphy, L Troidle, M Begley, M Begley, M Blunden, M Bonneville, M Brandes, M Eberl, M Eberl, M Eberl, M Eberl, M Eberl, M Fahim, M Kistowska, M Krishnan, M Pelletier, M Rohmer, MA Missinou, Mark A. Toleman, Martin S. Davey, Matthias Eberl, MC Devilder, MC Devilder, MI Hirsh, MJ Llewelyn, N Nathan, N Topley, Nicholas Topley, O Devuyst, P Choi, P Constant, PS Evans, R Medzhitov, RE Rojas, RM McLoughlin, S Amslinger, S Mujais, Simon J. Davies, Sinéad Heuston, SJ Davies, SM Hurst, SR Gill, T Ganz, Tanya Parish, TR Walsh, TW Rice, W Holtmeier, Y Kato, Y Neu, Y Tanaka, Y Zhang   +101 more
core   +5 more sources

Advances in Small Molecule Inhibitors Targeting the Bacterial Lipoprotein Transport System (Lol) in Gram‐Negative Bacteria

Chemistry – An Asian Journal, EarlyView.
The lipoprotein transport system (Lol) is a crucial target for combating multidrug‐resistant gram‐negative bacteria. This review discusses the structural and functional aspects of the LolABCDE complex, recent advances in small‐molecule inhibitors, and challenges, such as permeability and resistance.
Saemee Song, Su Yong Shim
wiley   +1 more source