The Changing Epidemiology of Carbapenemase-Producing Enterobacterales [PDF]
Objective Israeli hospitals were confronted with a major national outbreak of carbapenemase-producing Enterobacterales (CPE) starting in 2006, caused predominantly by monoclonal Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae ...
Khetam Hussein +7 more
doaj +3 more sources
Aztreonam: clinical and pharmacological characteristics at the present stage [PDF]
One of the urgent problems of modern health care is the growing resistance of microorganisms to antibiotics, including carbapenems, which until recently were considered as the drugs of choice in the treatment of life-threatening infections.
Popov D.A. +2 more
doaj +1 more source
Evaluation of Xpert Carba-R for detecting carbapenemase-producing organisms in South Africa
This study evaluated the performance of the Xpert Carba-R assay for detecting the five common carbapenemases in carbapenemase-producing organisms in Johannesburg, South Africa between April 2021 and September 2021.
Sanelisiwe T. Duze +5 more
doaj +1 more source
Application of AMRmap: «from the general to the specific» approach by the example of Klebsiella pneumoniae [PDF]
The options for the use of «Plot By» tab in the web platform AMRmap are reviewed in the article. Description of some functionality is supported by the specific examples, and Klebsiella pneumoniae was selected as a study object.
Vinogradova A.G., Kuzmenkov A.Yu.
doaj +1 more source
Global dissemination of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-negative bacteria (GNB) such as carbapenemase-producing Enterobacterales has resulted in reviving colistin as a final therapeutic alternative. Colistin resistance
Amal F. Makled +6 more
doaj +1 more source
Molecular characterization of extended-spectrum beta-lactamase-producing Enterobacterales isolates collected from blood culture in patients with hematological malignancies [PDF]
Objective. The objective of the study was to evaluate the prevalance of genes blaTEM, blaSHV and blaCTX-M among extended-spectrum beta-lactamase (ESBL)-producing Enterobacterales isolates collected from blood culture in patients with hematological ...
Khrulnova S.A. +4 more
doaj +1 more source
Detection of mcr-1-mediated resistance to polymyxins in Enterobacterales using colistin disk chelator application [PDF]
Objective. To evaluate the possibility of using the colistin disk chelator application (CDCA) method as simple and available screening tool for detection of mcr-1-mediated resistance to polymyxins in Enterobacterales. Materials and Methods.
Azyzov I.S., Martinovich А.А.
doaj +1 more source
Ceftolozane/tazobactam – the "new player" in a battle against multiresistant pathogens [PDF]
Ceftolozane/tazobactam is a new combined antibacterial agent for the treatment of infections caused by gram-negative microorganisms, P. aeruginosa in particular, including strains resistant to other clinically available antimicrobials.
Golub A.V., Kozlov R.S.
doaj +1 more source
The prevalence of multidrug-resistant gram-negative bacilli has increased worldwide. Critical care areas of most hospitals use carbapenem antibiotics for the empirical treatment of gram-negative bacterial (GNB) infections.
Amisha Piyush Khare +3 more
doaj +1 more source
In recent years, a wide range of clinical infections are being caused by carbapenem-resistant Enterobacterales, Acinetobacter baumannii and Pseudomonas aeruginosa. This is a matter of great concern, as carbapenem-resistant infections have fewer treatment
Gaurav Verma +6 more
doaj +1 more source

