Results 1 to 10 of about 35,054 (306)

Changing Epidemiology of Carbapenemases Among Carbapenem-Resistant Enterobacterales From United States Hospitals and the Activity of Aztreonam-Avibactam Against Contemporary Enterobacterales (2019–2021) [PDF]

Open Forum Infectious Diseases, 2023
Background As the frequency of metallo-β-lactamase (MBL)-producing Enterobacterales is increasing worldwide, effective antimicrobials to treat the infections caused by these organisms are urgently needed.
Hélio S. Sader, Rodrigo E. Mendes, Cecília G Carvalhaes, John H. Kimbrough, Mariana Castanheira   +4 more
openalex   +2 more sources

The Changing Epidemiology of Carbapenemase-Producing Enterobacterales [PDF]

Rambam Maimonides Medical Journal, 2022
Objective Israeli hospitals were confronted with a major national outbreak of carbapenemase-producing Enterobacterales (CPE) starting in 2006, caused predominantly by monoclonal Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae ...
Khetam Hussein, Yuval Geffen, Orna Eluk, Sigal Warman, Worood Aboalheja, Tamar Alon, Ibrahim Firan, Mical Paul   +7 more
doaj   +3 more sources

Antibiotic Treatment of Infections Caused by AmpC-Producing Enterobacterales [PDF]

Pharmacy
: AmpC enzymes are a class of beta-lactamases produced by Gram-negative bacteria, including several Enterobacterales. When produced in sufficient amounts, AmpCs can hydrolyze third-generation cephalosporins (3GCs) and piperacillin/tazobactam, causing ...
Cricca, Monica, Cristini, Francesco, Tebano, Gianpiero, Zaghi, Irene   +3 more
core   +2 more sources

Molecular mechanisms of tigecycline-resistance among Enterobacterales

Frontiers in Cellular and Infection Microbiology
The global emergence of antimicrobial resistance to multiple antibiotics has recently become a significant concern. Gram-negative bacteria, known for their ability to acquire mobile genetic elements such as plasmids, represent one of the most hazardous ...
Lukasz Korczak, P. Majewski, Dominika Iwaniuk, Paweł Sacha, Mariola Matulewicz, P. Wieczorek, Paulina Majewska, A. Wieczorek, Piotr Radziwon, E. Tryniszewska   +9 more
semanticscholar   +4 more sources

Risk factors for bloodstream infections due to carbapenem-resistant Enterobacterales: a nested case-control-control study [PDF]

Journal of Antimicrobial Chemotherapy
Background Carbapenem-resistant Enterobacterales (CRE) bloodstream infections (BSIs) are a major threat to patients. To date, data on risk factors have been limited, with low internal and external validity. In this multicentre study, risk factors for CRE
Antonelli, Massimo, Bartoloni, Alessandro, Rossolini, Gian Maria   +2 more
core   +2 more sources

Incidence of hospital-acquired infections due to carbapenem-resistant Enterobacterales and Pseudomonas aeruginosa in critically ill patients in Italy: a multicentre prospective cohort study [PDF]

Critical Care
BackgroundCarbapenem-Resistant Gram-Negative Bacteria, including Carbapenem-Resistant Enterobacterales (CRE) and Carbapenem-Resistant Pseudomonas aeruginosa (CRPA), are common causes of infections in intensive care units (ICUs) in Italy.ObjectiveThis ...
Aceto R., Ambretti S., Antonelli M., Brazzi L., Buffoli F., Cappanera S., Carelli S., Casari E., Casarotta E., Cattaneo S., Cavallero A., Cecconi M., Cortegiani A., Cuffaro R., Curtoni A., Cutuli S. L., Dalfino L., De Pascale G., Degl'Innocenti L., Di Biase F., Donati A., Fasano F. R., Fasciana T., Ferrari F., Foti G., Frattari A., Fumagalli R., Gherardi G., Giani T., Giarratano A., Girardis M., Gottin L., Guerrero F. A., Ippolito M., Mariottini A., Mattei A., Mazzariol A., Merola G., Milazzo M., Monti G., Montini L., Montrucchio G., Mosca A., Muroni A., Pasero D., Picciafuochi F., Ricciardi R., Rinaldi M., Rona R., Rubino S., Savini V., Sensi E., Serio L., Servillo G., Spanu T., Stufano M., Taiana M., Tanzarella E. S., Tiri B., Vargas M., Viaggi B., Viale P., Vidal Pereira M. A., Vismara C., Vittorielli E.   +64 more
core   +2 more sources

An Evidence-Based Multidisciplinary Approach Focused at Creating Algorithms for Targeted Therapy of BSIs, cUTIs, and cIAIs Caused by Enterobacterales in Critically Ill Adult Patients [PDF]

Infection and Drug Resistance, 2021
Milo Gatti,1,2 Bruno Viaggi,3 Gian Maria Rossolini,4– 6 Federico Pea,1,2 Pierluigi Viale1,7 1Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy; 2SSD Clinical Pharmacology, IRCCS Azienda Ospedaliero ...
Gatti M, Viaggi B, Rossolini GM, Pea F, Viale P   +4 more
doaj   +3 more sources

Colistin Resistance in Enterobacterales Strains – A Current View [PDF]

Polish Journal of Microbiology, 2019
Abstract Colistin is a member of cationic polypeptide antibiotics known as polymyxins. It is widely used in animal husbandry, plant cultivation, animal and human medicine and is increasingly used as one of the last available treatment options for patients with severe infections with carbapenem-resistant Gram-negative bacilli.
STEFANIUK, ELŻBIETA M., TYSKI, STEFAN
core   +5 more sources

Aztreonam: clinical and pharmacological characteristics at the present stage [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2023
One of the urgent problems of modern health care is the growing resistance of microorganisms to antibiotics, including carbapenems, which until recently were considered as the drugs of choice in the treatment of life-threatening infections.
Popov D.A., Zubareva N.A., Parshakov A.A.   +2 more
doaj   +1 more source

Evaluation of Xpert Carba-R for detecting carbapenemase-producing organisms in South Africa

African Journal of Laboratory Medicine, 2023
This study evaluated the performance of the Xpert Carba-R assay for detecting the five common carbapenemases in carbapenemase-producing organisms in Johannesburg, South Africa between April 2021 and September 2021.
Sanelisiwe T. Duze, Teena Thomas, Tshegofatso Pelego, Sabelle Jallow, Olga Perovic, Adriano Duse   +5 more
doaj   +1 more source