Results 11 to 20 of about 23,704 (212)

Hospital effluent: A reservoir for carbapenemase-producing Enterobacterales?

Science of The Total Environment, 2019
Antimicrobial resistance is a major public health concern. Carbapenemase-producing Enterobacterales (CPE) represent a significant health threat as some strains are resistant to almost all available antibiotics. The aim of this research was to examine hospital effluent and municipal wastewater in an urban area in Ireland for CPE.
Niamh Cahill, Louise O’Connor, Bláthnaid Mahon, Áine Varley, Elaine McGrath, Phelim Ryan, Martin Cormican, Carina Brehony, Keith A. Jolley, Martin Maiden, Sylvain Brisse, Dearbháile Morris   +11 more
openalex   +5 more sources

Antibiotic Treatment of Infections Caused by AmpC-Producing Enterobacterales [PDF]

Pharmacy
: AmpC enzymes are a class of beta-lactamases produced by Gram-negative bacteria, including several Enterobacterales. When produced in sufficient amounts, AmpCs can hydrolyze third-generation cephalosporins (3GCs) and piperacillin/tazobactam, causing ...
Cricca, Monica, Cristini, Francesco, Tebano, Gianpiero, Zaghi, Irene   +3 more
core   +5 more sources

The Changing Epidemiology of Carbapenemase-Producing Enterobacterales [PDF]

Rambam Maimonides Medical Journal, 2022
Objective: Israeli hospitals were confronted with a major national outbreak of carbapenemase-producing Enterobacterales (CPE) starting in 2006, caused predominantly by monoclonal Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae.
Khetam Hussein, Yuval Geffen, Orna Eluk, Sigal Warman, Worood Aboalheja, Tamar Alon, Ibrahim Firan, Mical Paul   +7 more
openaire   +3 more sources

Investigation of CTX-M Type Extended-Spectrum β-Lactamase, Carbapenem and Colistin Resistance in Enterobacterales Isolated From Dairy Cattle in Turkey. [PDF]

Vet Med Sci
This study reveals the presence of blaCTX‐M‐type ESBL‐producing E. coli in dairy cattle in Turkey, highlighting the zoonotic potential of antimicrobial resistance. No carbapenem or colistin resistance was detected. ABSTRACT Background The increasing prevalence of antimicrobial resistance in animals, particularly the spread of multidrug‐resistant ...
Yalcin M, Enginler SÖ, Kuşkucu MA, Sarılar M, Yalçın S, Küçükbasmacı Ö.   +5 more
europepmc   +2 more sources

Evaluation of Six Commercial and Noncommercial Colistin Resistance Diagnostics. [PDF]

Microbiologyopen
Colistin‐resistance diagnostics that are efficient, affordable, easy to use, with quicker turnaround times are important for surveillance and control of resistance. The in‐house Rapid NP test has very major errors but is both affordable and fast, with 92.16% sensitivity and 96.00% specificity.
Leshaba TMS, Mmatli M, Mbelle NM, Osei Sekyere J.   +3 more
europepmc   +2 more sources

Virulence Factors and Antibiotic Resistance of Enterobacterales

Microorganisms, 2022
In the class Gammaproteobacteria, Enterobacterales are Gram-negative, facultatively anaerobic bacteria [...]
Dobroslava Bujňáková, Nikola Puvača, Ivana Ćirković   +2 more
openaire   +3 more sources

Fast genome-based delimitation of Enterobacterales species

PLOS ONE, 2023
Average Nucleotide Identity (ANI) is becoming a standard measure for bacterial species delimitation. However, its calculation can take orders of magnitude longer than similarity estimates based on sampling of short nucleotides, compiled into so-called sketches. These estimates are widely used.
Julie E. Hernández-Salmerón, Tanya Irani, Gabriel Moreno-Hagelsieb   +2 more
openaire   +4 more sources

Activity of mecillinam against carbapenem-resistant Enterobacterales

Journal of Antimicrobial Chemotherapy, 2022
Abstract Background Despite the fact that carbapenem-resistant Enterobacterales (CRE) mostly cause urinary tract infections (UTIs), only few studies have focused on the efficacity of mecillinam against these CRE.
Emeraud, Cécile, Godmer, Alexandre, Girlich, Delphine, Vanparis, Océane, Mahamdi, Fériel, Creton, Elodie, Jousset, Agnès, Naas, Thierry, Bonnin, Rémy, Dortet, Laurent   +9 more
openaire   +3 more sources

Fosfomycin resistance mechanisms in Enterobacterales: an increasing threat

Frontiers in Cellular and Infection Microbiology, 2023
Antimicrobial resistance is well-known to be a global health and development threat. Due to the decrease of effective antimicrobials, re-evaluation in clinical practice of old antibiotics, as fosfomycin (FOS), have been necessary. FOS is a phosphonic acid derivate that regained interest in clinical practice for the treatment of complicated infection by
Vittoria Mattioni Marchetti, Vittoria Mattioni Marchetti, Vittoria Mattioni Marchetti, Jaroslav Hrabak, Jaroslav Hrabak, Ibrahim Bitar, Ibrahim Bitar   +6 more
openaire   +5 more sources

The world-wide spread of carbapenem-resistant Enterobacterales

One Health & Risk Management, 2020
Introduction. Gram-negative bacilli belonging to the order Enterobacterales are normal inhabitants of the human gut, which also are the most common causative agents of both nosocomial and community-acquired infections in patients of all ages.  Although not even a century has passed since Fleming's discovery of penicillin, the scientists have been ...
Tambic Andrasevic, A., Antal Antunovic, I.   +1 more
openaire   +5 more sources