Results 131 to 140 of about 40,926 (287)

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

ACID-BASE MODULATION OF LYSOZYME ACTIVITY IN MEDIUM FOR CULTIVATION OF ENTEROBACTERIA

Журнал микробиологии, эпидемиологии и иммунобиологии, 2015
Aim. Determination of modulating effect of acid-base state of medium for cultivation of enterobacteria on activity of C-type lysozyme. Materials and methods.
S. V Andryuschenko, N. B Perunova
doaj  

Commercial Day-Old Chicks in Nigeria Are Potential Reservoirs of Colistin- and Tigecycline-Resistant Potentially Pathogenic Escherichia coli

Antibiotics
Background: Frequent use of colistin (COL) and tetracyclines in the Nigerian poultry sector potentially triggers bacterial resistance against COL and tigecycline (TIG), which are last-line antibiotics used to treat multidrug-resistant infections.
Madubuike Umunna Anyanwu, Nkechi Harriet Ikenna-Ezeh, Simeon Chibuko Okafor, Chinaza Francisca Ezemuoka, Obichukwu Chisom Nwobi, Temitope Mofoluso Ogunniran, Lynda Onyinyechi Obodoechi, Onyinye Josephine Okorie-Kanu, Anthony Christian Mgbeahuruike, Ifeyinwa Riona Okosi, Ishmael Festus Jaja   +10 more
doaj   +1 more source

The degree of tetracycline influence on the intestine microbiocenosisand its correctionby "Bifiform - 21" [PDF]

, 2014
The paper presents a theoretical synthesis and scientific solution of scientific problem, grounded on the experimental side effects of broad-spectrum antibiotic (tetracycline hydrochloride) on qualitative and quantitative composition of the microbiota in
Holyar, O.I., Sokolenko, M.O., Sydorchuk, I.Y.   +2 more
core  

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

MORPHO-FUNCTIONAL CHARACTERISTIC OF ENTEROBACTERIA ADHESIVE ACTIVITY

Журнал микробиологии, эпидемиологии и иммунобиологии, 2015
Aim. Study adhesive activity of enterobacteria in the model of hemagglutination reaction with animal and avian erythrocytes and clarify structures responsible for adhesion in enterobacteria. Materials and methods.
M. M Tuigunov, D. T Gashimova, A. A Akhtareeva, Yu. Z Gabidullin, A. K Bulgakov, G. K Davletshina, G. A Idiatullina   +6 more
doaj  

Age influence on quality of shell and penetration in bacterial laying lightweight eggs

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
This study evaluated the influence of the bird’s age on the quality of the shell and percentage of bacterial penetration in commercial eggs. White-shelled commercial eggs were used, laid by light laying hens in their first laying cycle at 21, 39, 51, and
B.D. Smaniotto, A.F. Amarante, R. Altarugio, I.G.O. Silva, I.M.O. Corrêa, L.Q. Pereira, M.M.P. Sartori, R.L. Andreatti Filho, P.T.C. Guimarães-Okamoto, A.S. Okamoto   +9 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source