Results 41 to 50 of about 250,135 (303)

Molecular Characterization of AmpC β-lactamases in Enterobacteriaceae

, 2022
AmpC β-lactamases are enzymes that are resistant to β-lactams, such as penicillin and cephalosporin, but not cefoxitin and cefotetan. This study was conducted to characterize AmpC β-lactamases in Enterobacteriaceae.
Chitralekha Saikumar, D. Bindu
core   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

MIC breakpoints of XDR Enterobacterales Towards Polymyxin B, Colistin, and Tigecycline - Clinical Insights and Therapeutic Outcomes from A Descriptive Study

Journal of Pure and Applied Microbiology
The prevalence of antibiotic resistance among Gram-negative bacteria, particularly Enterobacterales, is rising. Extensively drug-resistant (XDR) Enterobacterales demonstrate nonsusceptibility to all except two or fewer classes of antibiotics, where it ...
R. Kalaivani, Arunava Kali, Joshy M. Easow   +2 more
doaj   +1 more source

Carbapenem-Resistant Enterobacteriaceae among In-Patients of Tertiary Hospitals in Southwest, Nigeria

Notulae Scientia Biologicae, 2018
The study assessed the incidence and risk factor associated with the occurrence of carbapenem-resistant Enterobacteriaceae (CRE) among hospitalized patients at three tertiary hospitals in Southwest, Nigeria.
Ibikunle I. ANIBIJUWON, Ifeoluwa Deborah GBALA, Olusoji O. ADEBISI   +2 more
doaj   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Vaginal microbiota and its changes due to the stress in women who had a medical abortion

Репродуктивная эндокринология
Objective of the study: to explore the impact of medical abortion on infections, stress, and the vaginal microbiota, providing essential insights into the associated risks and the need for comprehensive care. Materials and methods.
Vl.V. Podolskyi, V.V. Podolskyi, U.I. Botsyuk, N.V. Medvedovska, D.A. Emir-Useinova   +4 more
doaj   +1 more source

Bacilos Gram negativos entéricos y no fermentadores de la glucosa en pacientes con enfermedad periimplante

Biomédica: revista del Instituto Nacional de Salud, 2011
Introducción. Los implantes pueden ser colonizados por microorganismos de la biopelícula oral y así afectarse su salud. Entre los patógenos encontrados están los típicamente relacionados con periodontitis, como Aggregatibacter actinomycetemcomitans y ...
Jessika Consuegra, Sonia Jakeline Gutiérrez, Adriana Jaramillo, Ignacio Sanz, Gilberto Olave, Jorge Enrique Soto, Carlos Valencia, Adolfo Contreras   +7 more
doaj   +1 more source

Effects of metabiotic Bacillus subtilis for microbiocenosis formation in early-weaned piglets

Bulgarian Journal of Veterinary Medicine, 2023
This paper discusses the results of research related to cultivation of the probiotic microorganism B. subtilis on a grain-based nutrient medium of naked oat (Avena nuda) and studies the possibility of using metabolites as a liquid dietary supplement to ...
V. Popov, N. Naumov, G. Svazlyan
doaj   +1 more source

Esculin hydrolysis by Enterobacteriaceae [PDF]

Journal of Clinical Microbiology, 1977
Literature reports disagree concerning esculin hydrolysis in the family Enterobacteriaceae. A total of 2,490 strains of the family were investigated for esculin hydrolysis by two methods, the esculin spot test and the PathoTec incubation strip, which measures constitutive enzyme, and five growth-supporting methods, which determine both constitutive and
S C, Edberg, S, Pittman, J M, Singer
openaire   +2 more sources

Construction of a MOF‐Based Snap‐Top Delivery Nanosystem for Powerful Dual‐Responsive Synergistic Colitis Treatment

Advanced Science, EarlyView.
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li, Miao Xu, Heran Li, Huan Jiang, Xin Wang, Lianjun Ma, Ying‐Wei Yang   +6 more
wiley   +1 more source