Results 231 to 240 of about 1,015,161 (283)
Efficacy and Safety of Meropenem-Vaborbactam Versus Best Available Therapy for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections in Patients Without Prior Antimicrobial Failure: A Post Hoc Analysis. [PDF]
Bassetti M +4 more
europepmc +1 more source
Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response
Emerging research underscores the tumor‐specific colonization of microbiota and the role of intratumoral microbiota in cancer development and treatment resistance across multiple malignancies. Here, we provide a systematic review exploring the latest biotechnological advancements for studying low‐abundance intratumoral microbiota, their origins ...
Minhui Xu +7 more
wiley +1 more source
Network Biology: Current Status, Applications, Challenges, and Future Prospects
Network biology integrates molecular interaction, intracellular regulatory, single‐cell and multicellular, microbial and host–microbiome, disease, and interorgan networks across biological scales. Perturbation models, multiomics, spatial profiling, computational inference, mechanistic modeling, and AI enable dynamic network reconstruction and causal ...
Xinmeng Li +7 more
wiley +1 more source
The Lord of the Rings: Cysteine bonds crosslink the tail of siphovirus
Abstract Long, non‐contractile tails composed of helical hexameric protein repeats that assemble into continuous tubular structures characterize siphoviruses. The siphovirus tail tube protein gp39 contains two cysteine residues per monomer. Cryo‐electron microscopy revealed that these cysteines are oriented toward the interface between the rings, which
Simona Povilonienė +9 more
wiley +1 more source
Metronidazole and Eugenol Hybrids as an Alternative Against Multidrug‐Resistant Bacteria
Structures of the synthesized hybrid compounds AC1–AC8. Figure adapted from Pelozo et al. ABSTRACT Antibiotic resistance is a global threat to human and animal health, since several bacterial species have developed different forms of resistance. Therefore, it is essential to seek effective methods to combat bacterial resistance. Research indicates that
João Arthur de Oliveira Borges +13 more
wiley +1 more source
AF‐NALFA enables rapid, antibody‐free visual detection of amplified Salmonella DNA in milk. Using asymmetric PCR to generate ssDNA, the platform achieves high sensitivity without enrichment and enables naked‐eye detection without specialised readout equipment, providing a simple and cost‐effective approach for molecular screening in dairy quality ...
Leonardo Lopes‐Luz +6 more
wiley +1 more source
Schematic diagram of the core pathogenic pathway by which E. coli drives IgAN.E. coli expansion in IgAN is driven by host, environmental and ecological factors, and promotes disease progression via two core pathways: LPS‐induced immune activation and pyroptosis, and metabolite‐mediated remote regulation, leading to Gd‐IgA1 overproduction, mesangial ...
Yuxin Liu +7 more
wiley +1 more source
Biosurfactant‐producing bacteria were isolated from hydrocarbon‐contaminated industrial effluent in Dhaka, Bangladesh, using selective diesel liquid enrichment. Functional screening confirmed surfactant activity via oil displacement, drop‐collapse, and emulsification index assays.
Ummey Fatema Tun Amina +3 more
wiley +1 more source

