Results 231 to 240 of about 1,015,161 (283)

Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Emerging research underscores the tumor‐specific colonization of microbiota and the role of intratumoral microbiota in cancer development and treatment resistance across multiple malignancies. Here, we provide a systematic review exploring the latest biotechnological advancements for studying low‐abundance intratumoral microbiota, their origins ...
Minhui Xu   +7 more
wiley   +1 more source

Network Biology: Current Status, Applications, Challenges, and Future Prospects

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Network biology integrates molecular interaction, intracellular regulatory, single‐cell and multicellular, microbial and host–microbiome, disease, and interorgan networks across biological scales. Perturbation models, multiomics, spatial profiling, computational inference, mechanistic modeling, and AI enable dynamic network reconstruction and causal ...
Xinmeng Li   +7 more
wiley   +1 more source

The Lord of the Rings: Cysteine bonds crosslink the tail of siphovirus

open access: yesProtein Science, Volume 35, Issue 10, October 2026.
Abstract Long, non‐contractile tails composed of helical hexameric protein repeats that assemble into continuous tubular structures characterize siphoviruses. The siphovirus tail tube protein gp39 contains two cysteine residues per monomer. Cryo‐electron microscopy revealed that these cysteines are oriented toward the interface between the rings, which
Simona Povilonienė   +9 more
wiley   +1 more source

Metronidazole and Eugenol Hybrids as an Alternative Against Multidrug‐Resistant Bacteria

open access: yesChemistrySelect, Volume 11, Issue 39, 20 October 2026.
Structures of the synthesized hybrid compounds AC1–AC8. Figure adapted from Pelozo et al. ABSTRACT Antibiotic resistance is a global threat to human and animal health, since several bacterial species have developed different forms of resistance. Therefore, it is essential to seek effective methods to combat bacterial resistance. Research indicates that
João Arthur de Oliveira Borges   +13 more
wiley   +1 more source

An antibody‐free nucleic acid lateral flow assay (AF‐NALFA) for visual detection of amplified DNA from Salmonella enterica in milk

open access: yesInternational Journal of Dairy Technology, Volume 79, Issue 4, October‐December 2026.
AF‐NALFA enables rapid, antibody‐free visual detection of amplified Salmonella DNA in milk. Using asymmetric PCR to generate ssDNA, the platform achieves high sensitivity without enrichment and enables naked‐eye detection without specialised readout equipment, providing a simple and cost‐effective approach for molecular screening in dairy quality ...
Leonardo Lopes‐Luz   +6 more
wiley   +1 more source

Potential Roles of Escherichia coli in IgA Nephropathy: Evidence, Mechanistic Hypotheses and Microbiota‐Targeted Strategies

open access: yesMicrobial Biotechnology, Volume 19, Issue 10, October 2026.
Schematic diagram of the core pathogenic pathway by which E. coli drives IgAN.E. coli expansion in IgAN is driven by host, environmental and ecological factors, and promotes disease progression via two core pathways: LPS‐induced immune activation and pyroptosis, and metabolite‐mediated remote regulation, leading to Gd‐IgA1 overproduction, mesangial ...
Yuxin Liu   +7 more
wiley   +1 more source

Waste‐Contaminated Sites Near Dhaka City Harbour Specific Biosurfactant‐Producing Bacillus and Stutzerimonas Strains With Potential Biotechnological Applications

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 5, October 2026.
Biosurfactant‐producing bacteria were isolated from hydrocarbon‐contaminated industrial effluent in Dhaka, Bangladesh, using selective diesel liquid enrichment. Functional screening confirmed surfactant activity via oil displacement, drop‐collapse, and emulsification index assays.
Ummey Fatema Tun Amina   +3 more
wiley   +1 more source

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