Results 111 to 120 of about 11,402 (288)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
[Gram-negative bacteria of critical priority in ICU patients from a tertiary care hospital]. [PDF]
Rev Med Inst Mex Seguro Soc, 2023 Uc-Cachón AH +4 more
europepmc +1 more source
Intercambio de mecanismos de resistencia entre bacterias gram negativas. [PDF]
, 2013 La magnitud global de la resistencia a los antimicrobianos de uso clínico es alarmante adquiriendo una dimensión destacada en países de desarrollo intermedio quienes suelen ser cuantitativamente los más afectados por la emergencia de mecanismos de ...
Di Conza, José Alejandro +2 more
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Evaluación cinética de los dípteros como indicadores de la evolución del proceso de compostaje [PDF]
, 2010 Este trabajo buscó establecer el papel de ciertos organismos, en particular de artrópodos, en el proceso de compostaje, con el fin de establecer parámetros biológicos, físicos y químicos que permitan evaluar y garantizar la óptima calidad del material
Morales Mira, Gladis Estela +1 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Calidad microbiologica en tres hortalizas producidas en el Estado de México [PDF]
, 2017 La creciente preocupación de los consumidores por mantener una dieta sana y equilibrada, ha hecho que el consumo de hortalizas frescas aumente. Al mismo tiempo han incrementado los problemas de salud de los consumidores debido a la contaminación de ...
ROJAS PUEBLA, ITZEL, ROJAS PUEBLA, ITZEL
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Association of nirmatrelvir/ritonavir and remdesivir as treatment for SARS-CoV-2 infection in immunocompromised patients with hematologic malignancies. Series of four cases. [PDF]
Rev Esp Quimioter, 2023 Segura Fábrega A +12 more
europepmc +1 more source