Results 41 to 50 of about 822 (260)

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Carga bacteriana de los peces Cynoscion squamipinnis (Perciformes: Scianidae) y Lutjanus gutattus (Perciformes: Lutjanidae) en la cadena de comercialización, Costa Rica

Revista de Biología Tropical, 2009
Con el fin de determinar la calidad bacteriológica de los productos pesqueros en las diferentes etapas de comercialización, desde marzo del 2004 y hasta febrero del 2006, recolectamos muestras mensuales y realizamos análisis microbiológicos para ...
Carolina Marín, Cristian Fonseca, Sidey Arias, Irene Villegas, Andrea García, Hikaru Ishihara   +5 more
doaj  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

COMPARAÇÃO ENTRE COLETAS DE AMOSTRAS FECAIS PARA ANÁLISE MICROBIOLÓGICA EM CAMUNDONGOS ORALMENTE TOLERIZADOS

Brazilian Journal of Veterinary Medicine, 2013
A análise microbiológica de material fecal pode ser determinada a partir de coletas diretas e indiretas e posterior realização de ensaios bioquí- micos clássicos de identificação bacteriana, estando sua perfeita caracterização diretamente relacionada com
Camilla da Paixão Duarte, Maria de Fátima Sarro da Silva   +1 more
doaj  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Enterobacterias productoras de Betalactamasas de espectro extendido aisladas de pacientes ambulatorios y hospitalizados en un Laboratorio privado de Asunción

Memorias del Instituto de Investigaciones en Ciencias de la Salud, 2016
Entre los mecanismos de resistencia en enterobacterias, las Betalactamasas de espectro extendido (BLEE) juegan un papel de gran importancia. Estas enzimas son capaces de inactivar, además de las penicilinas y cefalosporinas de primera y segunda ...
Alicia Pereira, Norma Fariña, Marta de Vega, Fátima Rodríguez, Ladis de Figueredo   +4 more
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Evolución de la resistencia a los antibióticos de los microorganismos aislados de pie diabético infectado

Gaceta Médica Boliviana
Objetivos: evaluar la evolución de la resistencia a los antibióticos de los microorganismos aislados de pie diabético infectado en pacientes atendidos en el Hospital Clínico Viedma, en las gestiones 2014, 2016, 2018 y 2021.
Magaly Espinoza Antezana, Jans Velarde Negrete, Víctor Moya Pucho, Mariela Molina Peredo, Maria del Rosario Castro Soto   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source