Results 41 to 50 of about 41,662 (194)

The Prevalence and Clinical Impact of Transition Zone Anastomosis in Hirschsprung Disease: A Systematic Review and Meta-Analysis

Children, 2023
Background: Hirschsprung disease (HD) is characterized by absent neuronal innervation of the distal colonic bowel wall and is surgically treated by removing the affected bowel segment via pull-through surgery (PT).
Hosnieya Labib, Daniëlle Roorda, J. Patrick van der Voorn, Jaap Oosterlaan, L. W. Ernest van Heurn, Joep P. M. Derikx   +5 more
doaj   +1 more source

Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

Food Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao, Jiayao Wang, Yilian Huang, Na Zhang, Xiaodan Shi, Zongcai Tu, Zuohua Xie, Tao Yuan, Hongmei Yin   +8 more
wiley   +1 more source

State of the Art Bowel Management for Pediatric Colorectal Problems: Hirschsprung Disease

Children, 2023
After an initial pull-though, patients with Hirschsprung disease (HD) can present with obstructive symptoms, Hirschsprung-associated enterocolitis (HAEC), failure to thrive, or fecal soiling.
Elizaveta Bokova, Ninad Prasade, Sanjana Janumpally, John M. Rosen, Irene Isabel P. Lim, Marc A. Levitt, Rebecca M. Rentea   +6 more
doaj   +1 more source

Previable PROM in twins: A systematic review and meta‐analysis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Previable prelabor rupture of membranes (PROM) in twin pregnancies is a rare but high‐risk condition associated with substantial neonatal mortality and maternal morbidity. Management options include expectant management and selective reduction, though guidance is limited and based primarily on singleton data.
Marwan Odeh, Maya Frank Wolf, Forsan Kenaan, Raneen Sawaid Kaiyal, Ala Aiob, Lior Lowenstein, Inshirah Sgayer   +6 more
wiley   +1 more source

Janus kinase 1 inhibitors for treating immune checkpoint inhibitor-induced enterocolitis – report of two filgotinib-treated cases and literature review

Acta Oncologica
Background and purpose: Treatment of cancer with immune checkpoint inhibitors (ICIs) entails a risk of immune-related adverse events (irAEs). Data on the treatment of immune-related enterocolitis (irEC) in patients with inadequate symptom control after ...
Henrik Ekedahl, Gudbjörg Sigurjonsdottir, Viktoria Bergqvist, Björn Båtshake, Ana Carneiro, Jan Marsal   +5 more
doaj   +1 more source

Breastfeeding in term and preterm infants with and without growth restriction: A 50‐year analysis of incidence and duration

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The aim of the present study was to analyze breastfeeding rates and duration in relation to preterm birth, fetal growth restriction, and demographics over five decades. Methods This retrospective cohort study included 1559 individuals (aged 4–52 years) and their parents from the University Medical Center Mainz, Germany.
Achim Fieß, Alica Hartmann, Eva Mildenberger, Julia Winter, Mareike Ernst, Jonas Tesarz, Michael S. Urschitz, Norbert Pfeiffer, Alexander K. Schuster, Sandra Gißler, Dirk Wackernagel   +10 more
wiley   +1 more source

Utility of GutCheck-NEC and e-NEC Scoring Systems in Assessing the Risk of Necrotizing Enterocolitis in Preterm Infants

Güncel Pediatri
Introduction: Necrotizing enterocolitis (NEC) is one of the leading gastrointestinal emergencies causing significant morbidity and mortality in premature neonates. This study aimed to evaluate the effectiveness of the GutCheck-NEC (GCN) and e-NEC scoring
Berna Egehan Örüncü, Nuriye Ebru Ergenekon, İbrahim Murat Hirfanoğlu, Canan Türkyılmaz, Eray Esra Önal, Esin Koç   +5 more
doaj   +1 more source

Preterm assisted vaginal births and associated maternal and neonatal outcomes: A retrospective study in a tertiary hospital

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objectives This study compares maternal and neonatal outcomes between preterm vacuum and forceps‐assisted vaginal births and evaluates preterm outcomes between those <34 + 0 weeks gestation to those ≥34 + 0. Methods This study is a single‐center retrospective cohort study of all singleton assisted vaginal births during 2014–2021. Delivery data
Caroline Leps, Paul Naseef, Elham Almoli, Daniel Kane, Nancy Nancy, Melissa Walker, John Kingdom, Sebastian R. Hobson   +7 more
wiley   +1 more source

Most costly and prevalent reasons for hospitalization in children with medical complexity in Ontario, Canada

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Children with medical complexity (CMC) have chronic health conditions often associated with functional limitations. CMC comprise 1%–5% of the pediatric population. In Canada, their care accounts for one‐third of pediatric health spending.
Erin Hessey, Thaksha Thavam, Sanjay Mahant, Eyal Cohen, Jingqin Zhu, Francine Buchanan, Teresa To, Peter J. Gill, Ontario Pediatric Hospital Care Study Group (OPHCSG) and the Canadian Paediatric Inpatient Research Network (PIRN), Wenjia Chen, Ronald Cohn, Mairead Green, Matt Hall, Kate Langrish, Colin Macarthur, Myla Moretti, Patricia Parkin, Michelle Quinlan, Ann Bayliss, Ronik Kanani, Sean Murray, Catherine Pound, Mahmoud Sakran, Anupam Sehgal, Sepi Taheri, Gita Wahi   +25 more
wiley   +1 more source

Renal function impairment in children with intestinal failure receiving parenteral nutrition: A descriptive cohort study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Children with intestinal failure are at risk for kidney dysfunction; however, the contributing factors are not well established. We aimed to describe risk factors associated with glomerular and tubular renal dysfunction in children with intestinal failure.
Amanda M. Braga da Mata, Heitor Pons Leite, Eduardo F. Hatanaka, Mariana Janiques Barcia Magalhães Fonseca, Marta Liliane de Almeida Maia, Giovana S. G. Sabio, Maria Fernanda C. de Camargo, Paulo C. Koch Nogueira   +7 more
wiley   +1 more source