Results 61 to 70 of about 43,132 (255)

A novel central line securement vest reduces line trauma and improves quality of life in patients with intestinal failure

JPGN Reports, EarlyView.
Abstract Objective We sought to assess the impact of a novel central line securement vest on the rate of line complications (trauma, infections, and replacements), and measures of quality of life (QOL) in pediatric patients with intestinal failure. Methods We enrolled patients at a single tertiary pediatric center.
Ryan E. St. Pierre‐Hetz, Kimberly S. Ackerman, Angelica M. Cercone, Jane Anne Yaworski, Clifton W. Callaway, Jeffrey A. Rudolph, Mioara D. Manole   +6 more
wiley   +1 more source

Glutamine and partially hydrolyzed guar gum promote intestinal adaptation and modulate small intestinal microbiota in high‐output stoma: A case report

JPGN Reports, EarlyView.
Abstract We report a case of a very low‐birth‐weight infant with a high‐output stoma following necrotizing enterocolitis. The patient exhibited villous atrophy and microbial dysbiosis. Supplementation with glutamine and partially hydrolyzed guar gum (PHGG) was initiated, leading to reduced stoma output, improved feeding tolerance, and appropriate ...
Yunosuke Kawaguchi, Keita Terui, Ayako Takenouchi, Shugo Komatsu, Ryohei Shibata, Katsuhiro Nishimura, Shota Takiguchi, Yukiko Iwase, Rei Hashimoto, Keisuke Matsusaka, Yoshiteru Osone, Jun‐ichiro Ikeda, Tomoro Hishiki   +12 more
wiley   +1 more source

Longitudinal analysis of gut microbiota dysbiosis and bacterial signatures predictive of postoperative enterocolitis in children with Hirschsprung disease [PDF]

Clinical and Experimental Pediatrics
Background We aimed to investigate differences in gut microbiota between patients with Hirschsprung disease (HSCR) and healthy children; assess longitudinal changes in the microbiota of patients with HSCR from diagnosis through postoperative period; and ...
Sireekarn Chantakhow, Chanon Kunasol, Jiraporn Khorana, Kanokkan Tepmalai, Nipon Chattipakorn, Siriporn C. Chattipakorn   +5 more
doaj   +1 more source

A preterm neonate with infantile liver failure syndrome 1 due to leucyl‐tRNA synthetase 1 gene (LARS1) mutations with a histopathologic phenotype of neonatal hemochromatosis

JPGN Reports, EarlyView.
Abstract We report a case of a premature, growth‐restricted female infant with feeding intolerance and coagulopathy, treated initially for sepsis, who progressed to neonatal acute liver failure and end‐stage hepatic encephalopathy after a prolonged hospitalization with extensive diagnostic evaluation, and was found by autopsy to have histopathologic ...
Adrienne Bruder, Naomi Laventhal, Raja Rabah, Jacqueline Meadow   +3 more
wiley   +1 more source

Pediatric Clostridiodes difficile infection with toxic megacolon successfully treated with fecal microbiota transplantation

JPGN Reports, EarlyView.
Abstract The rising incidence of pediatric Clostridioides difficile infection (CDI), particularly in medically complex patients, calls for novel, individualized treatments. While fecal microbiota transplantation (FMT) is well‐described for recurrent CDI, this report describes the first pediatric case of fulminant CDI with toxic megacolon successfully ...
Dana McCarney, Pamela Chen, Jenna Simes, Stacy A. Kahn   +3 more
wiley   +1 more source

Barriers and facilitators to the national scale‐up of a preterm standardised parenteral nutrition system: A mixed‐methods evaluation

JPGN Reports, EarlyView.
Abstract Objective Standardising parenteral nutrition (PN) care for preterm infants is recommended to enhance safety, outcomes and efficiency, however implementation at scale remains challenging. In 2021, Ireland scaled‐up a standardised parenteral nutrition (SPN) system comprising SPN formulations and dosing protocol.
Sarah Fenton, Ann‐Marie Brennan, Aoife Fleming, Vicki Livingstone, Brendan Murphy, Aileen Murphy, Eugene Dempsey, Ciara Heavin   +7 more
wiley   +1 more source

Growth and human milk intake outcomes from postdischarge feedings among very‐low‐birth‐weight preterm infants: A systematic review

Nutrition in Clinical Practice, EarlyView.
Abstract Background Preterm infants of <34 weeks gestation or <1500 g are at risk for postnatal growth failure and often require nutrition support after discharge. Despite expert recommendations for postdischarge human milk (HM) fortification or nutrient‐enriched formula feeding, the effects of current feeding strategies on growth and HM intake remain ...
Tara Rebele, Allison Gomes, Melanie Newkirk, Mina Ghajar, Laura Byham‐Gray, Jane Ziegler   +5 more
wiley   +1 more source

The transformative potential of artificial intelligence in pediatric medicine: Current applications, methodological challenges, and future directions

Pediatric Investigation, EarlyView.
Artificial intelligence (AI) offers transformative potential for paediatric diagnosis and treatment, yet implementation faces unique challenges, including data scarcity, algorithmic bias, and children's developmental physiology. This review examines current applications and charts a path toward transparent, equitable, and trustworthy AI in child health.
Ruisong Wang, Xiaoman Ding, Wanyue Zhang, Tieliu Shi   +3 more
wiley   +1 more source

The Performance of Selective Screening Ultrasound to Detect the Small‐for‐Gestational‐Age Foetus: A Prospective Cohort Study Nested Within the DESiGN Randomised Control Trial

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Evidence on the performance of foetal growth ultrasound parameters to detect the Small‐for‐Gestational‐Age (SGA) foetus for a selective cohort is limited. We report the performance of estimated foetal weight under the 10th percentile (EFW < 10th) at the last selective screening ultrasound to detect SGA based on gestational age of ...
Charles Arcus, James Elhindi, Chivon Winsloe, Andrew Copas, Sophie Relph, Annette Briley, Kirstie Coxon, Mark Johnson, Asma Khalil, Deborah A. Lawlor, Christoph Lees, Neil Marlow, Louise Page, Andrew Shennan, Jane Sandall, Tanya Nippita, Matias C. Vieira, Dharmintra Pasupathy   +17 more
wiley   +1 more source

Phenotyping Preeclampsia Using Unsupervised Machine Learning: A Prospective Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To explore clinically meaningful phenotypes of preeclampsia using unsupervised machine learning. Design Prospective cohort study. Setting BCNatal, a tertiary maternal‐foetal medicine centre (Barcelona, Spain). Population A total of 482 pregnant women diagnosed with preeclampsia between August 2013 and April 2024.
Ohad Houri, Lina Youssef, Francesca Crovetto, Maria Borrell, Maddalena Crimella, Maria Giulia Ferrante, Rommy H. Novoa, Irene Casas, Noelia Encabo, Leticia Benitez, Marta Larroya, Anna Peguero, Eva Meler, Sara Castro‐Barquero, Bart Bijnens, Francesc Figueras, Eduard Gratacos, Gabriel Bernardino, Fàtima Crispi   +18 more
wiley   +1 more source