Results 61 to 70 of about 117,551 (361)

Born too early and too small: higher order cognitive function and brain at risk at ages 8–16 [PDF]

, 2019
Prematurity presents a risk for higher order cognitive functions. Some of these deficits manifest later in development, when these functions are expected to mature. However, the causes and consequences of prematurity are still unclear.
Clark, Chris A., Clayden, Jonathan D., Córcoles Parada, Marta, Giménez Mateo, Rocío, López, Leidy, Mansilla, Francisco, Martínez, Andrés, Muñoz López, Mónica, Onsurbe, Ignacio, Pérez Hernández, Elena, San Román, Paloma, Serrano del Pueblo, Víctor, Ubero Martínez, Mar   +12 more
core   +5 more sources

Paneth-like cells disruption and intestinal dysbiosis in the development of enterocolitis in an iatrogenic rectosigmoid hypoganglionosis rat model

Frontiers in Surgery
BackgroundHypoganglionosis resembles Hirschsprung disease (HSCR) which is characterized by severe constipation. Enterocolitis due to hypoganglionosis or Hirschsprung-associated enterocolitis (HAEC) is a life-threatening complication of both diseases ...
Iskandar Rahardjo Budianto, Kusmardi Kusmardi, Andi Muh. Maulana, Andi Muh. Maulana, Somasundaram Arumugam, Rejina Afrin, Vivian Soetikno   +6 more
doaj   +1 more source

Estimating Neonatal Necrotizing Enterocolitis Based on Feeding Practices

Children, 2021
(1) Background: The relationship between enteral nutrition and neonatal necrotizing enterocolitis (NEC) among premature neonates is still unclear. The present work was designed to assess the relationship between NEC and feeding strategies compared to ...
Miguel Baños-Peláez, Valeria Avila-Sosa, Luis Alberto Fernández-Carrocera, Gabriela González-Pérez, Sandra Carrera-Muiños, Maria Antonieta Rivera-Rueda, Guadalupe Cordero-González, Silvia Romero, Alejandra Coronado-Zarco, Estibalitz Laresgoiti-Servitje, Claudine Irles   +10 more
doaj   +1 more source

Diagnostic performance of noninvasive tests for cytomegalovirus ileocolitis: a systematic review and meta-analysis [PDF]

Intestinal Research
Background/Aims Diagnosis of cytomegalovirus (CMV) ileocolitis traditionally requires colonoscopy with tissue biopsy. Due to potential complications in high-risk patients, there is growing interest in serum and stool tests for diagnosing this condition ...
Thanaboon Chaemsupaphan, Onuma Sattayalertyanyong, Julajak Limsrivilai   +2 more
doaj   +1 more source

A Hirschsprung Pull-through, “with a Twist”

European Journal of Pediatric Surgery Reports, 2020
Hirschsprung disease is the most common neurocristopathy in children, resulting in the congenital loss of enteric ganglia. Surgery, which involves resecting the aganglionic segment and restoring bowel continuity, usually results in a good outcome ...
Hira Ahmad, Devin R. Halleran, Raquel Quintanilla, Alessandra C. Gasior, Richard J. Wood, Marc A. Levitt   +5 more
doaj   +1 more source

Recent advances in understanding necrotizing enterocolitis

F1000Research, 2019
Necrotizing enterocolitis is a devastating intestinal disease affecting preterm infants. In spite of ongoing research and advancement in neonatal care, mortality remains high, especially in infants with advanced disease.
Mashriq Alganabi, Carol Lee, E. Bindi, Bo Li, A. Pierro   +4 more
semanticscholar   +1 more source

Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

Advanced Science, EarlyView.
The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli, Daniel Levy, Alyssa Schledwitz, Natalia Sampaio Moura, Mitali Sarkar, Talia J. Solomon, Emily H. Powsner, Raith Nowak, Zuzanna Mamczarz, Christopher J. Bridgeman, Sulayman Khan, Andrew Hui, Nidhi Anne, Laura Reus, William E. Bentley, Jean‐Pierre Raufman, Steven M. Jay   +16 more
wiley   +1 more source

Immune Dysregulation in Cancer Patients Undergoing Immune Checkpoint Inhibitor Treatment and Potential Predictive Strategies for Future Clinical Practice

Frontiers in Oncology, 2018
Realization of the full potential of immune checkpoint inhibitor-targeted onco-immunotherapy is largely dependent on overcoming the obstacles presented by the resistance of some cancers, as well as on reducing the high frequency of immune-related adverse
Ronald Anderson, Ronald Anderson, Bernardo L. Rapoport, Bernardo L. Rapoport   +3 more
doaj   +1 more source

Association of intestinal alkaline phosphatase with necrotizing enterocolitis among premature infants [PDF]

, 2019
Importance: Necrotizing enterocolitis (NEC) in preterm infants is an often-fatal gastrointestinal tract emergency. A robust NEC biomarker that is not confounded by sepsis could improve bedside management, lead to lower morbidity and mortality, and permit
Barkemeyer, Brian, Buckley, Rebecca, Davis, Porcha, Fang, Zhide, Gerber, Zeromeh, Gong, Qingqing, Good, Misty, Heath, Maya, Kim, Sunyoung, Linneman, Laura, Penn, Duna   +10 more
core   +1 more source

The Neonatal Microbiome and Necrotizing Enterocolitis. [PDF]

, 2010
Necrotizing enterocolitis (NEC) is a devastating disorder that affects approximately 10% of premature infants. Its mortality remains high (15-30%), and its cause remains unknown.
Aaron Hamvas, Barbara Warner, Barbara Warner, Erica Sodergren, George Weinstock, Phillip Tarr, Vincent Magrini, William Shannon   +7 more
core   +2 more sources