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Microbial regulation of enteroendocrine cells

Med, 2021
There has been an enormous interest to investigate impact of gut microbiota on host physiology over the past decade. To further understand its role at organismal level, it is important to delineate host-microbiota interaction at tissue and cell level.
Arora, Tulika   +3 more
openaire   +3 more sources

Piperine, as a TAS2R14 agonist, stimulates the secretion of glucagon-like peptide-1 in the human enteroendocrine cell line Caco-2.

Food & Function, 2021
Piperine is reported to ameliorate common metabolic diseases, however, its molecular mechanism is still unclear. In the present study, we examined whether piperine could stimulate glucagon-like peptide-1 (GLP-1) secretion in a human enteroendocrine cell ...
Ting-ting Huang   +4 more
semanticscholar   +1 more source

Enteroendocrine cell types revisited.

Current Opinion in Pharmacology, 2013
The GI-tract is profoundly involved in the control of metabolism through peptide hormones secreted from enteroendocrine cells scattered throughout the gut mucosa. A large number of recently generated transgenic reporter mice have allowed for direct characterization of biochemical and cell biological properties of these previously highly elusive ...
M. S. Engelstoft   +3 more
semanticscholar   +4 more sources

Enteroendocrine cells and lipid absorption

Current Opinion in Lipidology, 2011
To examine recent papers linking enteroendocrine cells to lipid absorption.Specific inactivation of the proendocrine transcription factor neurogenin 3 (Ngn3) in the intestine leads to a loss of enteroendocrine cells, growth retardation, impaired lipid absorption and a high mortality during the weaning period.
Mellitzer, Georges, Gradwohl, Gerard
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Enteroendocrine cells in the Echinodermata

Cell and Tissue Research, 2019
Enteroendocrine cells are endocrine-like cells found in the luminal epithelia of the digestive tract. These cells have been described in most animal phyla. In echinoderms, the cells have been described mainly in organisms of the class Asteroidea (sea stars) and Holothuroidea (sea cucumbers).
José E. García-Arrarás   +2 more
openaire   +2 more sources

Chemosensing in enteroendocrine cells: mechanisms and therapeutic opportunities

Current Opinion in Endocrinology, Diabetes & Obesity, 2021
Purpose of review Enteroendocrine cells (EECs) are scattered chemosensory cells in the intestinal epithelium that release hormones with a wide range of actions on intestinal function, food intake and glucose homeostasis. The mechanisms by which gut hormones are secreted postprandially, or altered by antidiabetic agents and ...
Ming, Yang   +2 more
openaire   +2 more sources

Enteroendocrine cells in gastrointestinal pathophysiology

Current Opinion in Pharmacology, 2013
Enteroendocrine cells in the gastrointestinal tract play an important role in the regulation of appetite and digestive responses through the secretion of peptides. Their involvement in gastrointestinal diseases has been acknowledged, but relatively few studies have sought to clearly define their role in the pathogenesis or as therapeutic targets ...
Harrison, Elizabeth   +2 more
openaire   +3 more sources

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