Cardiometabolic and molecular adaptations to 6-month intermittent fasting in middle-aged men and women with overweight: secondary outcomes of a randomized controlled trial. [PDF]
Barve RA +10 more
europepmc +1 more source
Senecavirus a can replicate in apical-out porcine intestinal organoids and induce stress granules and innate immune response. [PDF]
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Fatty acid transport protein 2 inhibition enhances glucose tolerance through α cell-mediated GLP-1 secretion. [PDF]
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The Drosophila G protein-coupled receptor, GulpR, is essential for lipid mobilization in response to nutrient-limitation. [PDF]
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Coated glucose microbeads stimulate enteric hormone release and improve glucose tolerance in Phase 1 and 2 clinical trials. [PDF]
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Microbial regulation of enteroendocrine cells
Med, 2021There has been an enormous interest to investigate impact of gut microbiota on host physiology over the past decade. To further understand its role at organismal level, it is important to delineate host-microbiota interaction at tissue and cell level.
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Piperine is reported to ameliorate common metabolic diseases, however, its molecular mechanism is still unclear. In the present study, we examined whether piperine could stimulate glucagon-like peptide-1 (GLP-1) secretion in a human enteroendocrine cell ...
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Chemosensing in enteroendocrine cells: mechanisms and therapeutic opportunities
Current Opinion in Endocrinology, Diabetes & Obesity, 2021Purpose of review Enteroendocrine cells (EECs) are scattered chemosensory cells in the intestinal epithelium that release hormones with a wide range of actions on intestinal function, food intake and glucose homeostasis. The mechanisms by which gut hormones are secreted postprandially, or altered by antidiabetic agents and ...
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Enteroendocrine cells in the Echinodermata
Cell and Tissue Research, 2019Enteroendocrine cells are endocrine-like cells found in the luminal epithelia of the digestive tract. These cells have been described in most animal phyla. In echinoderms, the cells have been described mainly in organisms of the class Asteroidea (sea stars) and Holothuroidea (sea cucumbers).
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Enteroendocrine cell types revisited.
Current Opinion in Pharmacology, 2013The GI-tract is profoundly involved in the control of metabolism through peptide hormones secreted from enteroendocrine cells scattered throughout the gut mucosa. A large number of recently generated transgenic reporter mice have allowed for direct characterization of biochemical and cell biological properties of these previously highly elusive ...
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