Results 191 to 200 of about 4,441,967 (229)

Mapping the druggable targets displayed by human colonic enteroendocrine cells

Bewick G, Lei Y, Bohl B, Meyer L, Jacobs M, Haq N, Yang X, Hayee BH, Murphy K, Hashemi P.   +9 more
europepmc   +2 more sources

RET Signaling Persists in the Adult Intestine and Stimulates Motility by Limiting PYY Release From Enteroendocrine Cells. [PDF]

Gastroenterology
Shepherd A, Feinstein L, Sabel S, Rastelli D, Mezhibovsky E, Matthews L, Muppirala A, Robinson A, Sharma KR, ElSeht A, Zeve D, Breault DT, Gershon MD, Rao M.   +13 more
europepmc   +1 more source

Cover 2 - Enteroendocrine Cell Neuropods

Cellular and Molecular Gastroenterology and Hepatology, 2019
openaire   +1 more source

Aloe emodin promotes mucosal healing by modifying the differentiation fate of enteroendocrine cells via regulating cellular free fatty acid sensitivity. [PDF]

Acta Pharm Sin B
Bao W, Lyu J, Feng G, Guo L, Zhao D, You K, Liu Y, Li H, Du P, Chen D, Shen X.   +10 more
europepmc   +1 more source

Dietary L-Glu sensing by enteroendocrine cells adjusts food intake via modulating gut PYY/NPF secretion. [PDF]

Nat Commun
Gao J, Gao J, Zhang S, Deng P, Wu Z, Lemaitre B, Zhai Z, Guo Z.   +7 more
europepmc   +1 more source

Enteroendocrine L cells and Metabolic Disease

, 2018
openaire   +2 more sources

The MicroRNA Repertoire in Enteroendocrine Cells: Identification of miR-375 as a Potential Regulator of the Enteroendocrine Lineage [PDF]

Endocrinology, 2015
Micro-RNAs (miRNAs) are crucial for many biological processes, but their role in the enteroendocrine development and differentiation has been neglected due to the elusive nature of the enteroendocrine cells. However, transgenic mice expressing fluorescent reporter proteins under the control of promoters for Cck, Gpr41, and Lgr5, ie, two different ...
Natalia Petersen, Thue W Schwartz, Lina A Knudsen   +2 more
exaly   +5 more sources

Identification of Enteroendocrine Regulators by Real-Time Single-Cell Differentiation Mapping

Cell, 2019
Homeostatic regulation of the intestinal enteroendocrine lineage hierarchy is a poorly understood process. We resolved transcriptional changes during enteroendocrine differentiation in real time at single-cell level using a novel knockin allele of ...
Joep Beumer, Hans Clevers, Kai Kretzschmar   +2 more
exaly   +2 more sources

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Enteroendocrine cell differentiation and function in the intestine

Current Opinion in Endocrinology, Diabetes & Obesity, 2022
Purpose of review The intestinal enteroendocrine cells (EECs) are specialized hormone-secreting cells that respond to both circulating and luminal cues. Collectively, EECs constitute the largest endocrine organ of the body and signal to a multitude of targets including locally to neighboring intestinal cells, enteric neurons ...
J Guillermo, Sanchez, Jacob R, Enriquez, James M, Wells   +2 more
openaire   +2 more sources