Results 1 to 10 of about 20,295 (209)

Enteroendocrine cell regulation of the gut-brain axis [PDF]

Frontiers in Neuroscience, 2023
Enteroendocrine cells (EECs) are an essential interface between the gut and brain that communicate signals about nutrients, pain, and even information from our microbiome.
Joshua R. Barton, Annie K. Londregan, Tyler D. Alexander, Ariana A. Entezari, Manuel Covarrubias, Scott A. Waldman, Scott A. Waldman   +6 more
doaj   +4 more sources

Enteroendocrine cell lineages that differentially control feeding and gut motility [PDF]

eLife, 2023
Enteroendocrine cells are specialized sensory cells of the gut-brain axis that are sparsely distributed along the intestinal epithelium. The functions of enteroendocrine cells have classically been inferred by the gut hormones they release.
Marito Hayashi, Judith A Kaye, Ella R Douglas, Narendra R Joshi, Fiona M Gribble, Frank Reimann, Stephen D Liberles   +6 more
doaj   +2 more sources

A hierarchical transcription factor cascade regulates enteroendocrine cell diversity and plasticity in Drosophila [PDF]

Nature Communications, 2022
Here the authors elucidate a simple transcription factor code that underlies the complex genetic specification of enteroendocrine cell (EE) subtypes, and reveal significant cellular plasticity amongst EE subtypes.
Xingting Guo, Yongchao Zhang, Huanwei Huang, Rongwen Xi   +3 more
doaj   +2 more sources

The Cellular Diversity and Transcription Factor Code of Drosophila Enteroendocrine Cells

Cell Reports, 2019
Summary: Enteroendocrine cells (EEs) in the intestinal epithelium have important endocrine functions, yet this cell lineage exhibits great local and regional variations that have hampered detailed characterization of EE subtypes.
Xingting Guo, Chang Yin, Fu Yang, Yongchao Zhang, Huanwei Huang, Jiawen Wang, Bowen Deng, Tao Cai, Yi Rao, Rongwen Xi   +9 more
doaj   +3 more sources

Elevated Serum Chromogranin-A and Characteristic Duodenal Enteroendocrine Cell Distribution in Pancreatic Fibrosis and Chronic Pancreatitis Compared with Other Dyspeptic Disorders: A Case Series Study [PDF]

Diagnostics
Background: Prior research has reported increased expression of duodenal chromogranin-A (CgA), secreted by enteroendocrine cells (EECs), in association with pancreatic fibrosis.
Chung-Tsui Huang, Yao-Jen Liang
doaj   +2 more sources

The Effects of Fecal Microbiota Transplantation on the Symptoms and the Duodenal Neurogenin 3, Musashi 1, and Enteroendocrine Cells in Patients With Diarrhea-Predominant Irritable Bowel Syndrome

Frontiers in Cellular and Infection Microbiology, 2021
IntroductionInteractions between the gut microbiota and enteroendocrine cells play important role in irritable bowel syndrome (IBS). Reduced stem cell densities and their differentiation into enteroendocrine cells may cause abnormal densities of the ...
Tarek Mazzawi, Tarek Mazzawi, Tarek Mazzawi, Magdy El-Salhy, Magdy El-Salhy, Magdy El-Salhy, Gülen Arslan Lied, Gülen Arslan Lied, Gülen Arslan Lied, Trygve Hausken, Trygve Hausken, Trygve Hausken   +11 more
doaj   +1 more source

Microbial Control of Intestinal Homeostasis via Enteroendocrine Cell Innate Immune Signaling. [PDF]

Trends Microbiol, 2020
Watnick PI, Jugder BE.
europepmc   +2 more sources

Discovery of a hidden form of neuropeptide F and its presence throughout the CNS–gut axis in the mud crab, Scylla olivacea

Frontiers in Marine Science, 2022
The mud crab Scylla olivacea (Scyol) is an economically crucial crustacean species in Thailand, due to its high market demand and nutritional value. The neuropeptide F (NPF) has been implicated in the coordinated regulation of feeding and metabolism in ...
Thanapong Kruangkum, Thanapong Kruangkum, Supawadee Duangprom, Sineenart Songkoomkrong, Charoonroj Chotwiwatthanakun, Charoonroj Chotwiwatthanakun, Rapeepun Vanichviriyakit, Rapeepun Vanichviriyakit, Prasert Sobhon, Napamanee Kornthong   +9 more
doaj   +1 more source

Enteroendocrine cells are specifically marked by cell surface expression of claudin-4 in mouse small intestine. [PDF]

PLoS ONE, 2014
Enteroendocrine cells are solitary epithelial cells scattered throughout the gastrointestinal tract and produce various types of hormones, constituting one of the largest endocrine systems in the body.
Takahiro Nagatake, Harumi Fujita, Nagahiro Minato, Yoko Hamazaki   +3 more
doaj   +1 more source

Revisiting the concept of incretin and enteroendocrine L-cells as type 2 diabetes mellitus treatment

Pharmacological Research, 2022
The significant growth in type 2 diabetes mellitus (T2DM) prevalence strikes a common threat to the healthcare and economic systems globally. Despite the availability of several anti-hyperglycaemic agents in the market, none can offer T2DM remission ...
Kok-Hou Lok, Nicholas J. Wareham, Rajesh Sreedharan Nair, Chee Wun How, Lay-Hong Chuah   +4 more
doaj   +1 more source