Results 11 to 20 of about 20,295 (209)

Enteroendocrine Cells Support Intestinal Stem-Cell-Mediated Homeostasis in Drosophila

Cell Reports, 2014
Summary: Intestinal stem cells in the adult Drosophila midgut are regulated by growth factors produced from the surrounding niche cells including enterocytes and visceral muscle. The role of the other major cell type, the secretory enteroendocrine cells,
Alla Amcheslavsky, Wei Song, Qi Li, Yingchao Nie, Ivan Bragatto, Dominique Ferrandon, Norbert Perrimon, Y. Tony Ip   +7 more
doaj   +6 more sources

Enteroendocrine cell differentiation and function in the intestine. [PDF]

Curr Opin Endocrinol Diabetes Obes, 2022
Purpose of review The intestinal enteroendocrine cells (EECs) are specialized hormone-secreting cells that respond to both circulating and luminal cues. Collectively, EECs constitute the largest endocrine organ of the body and signal to a multitude of targets including locally to neighboring intestinal cells, enteric neurons ...
Sanchez JG, Enriquez JR, Wells JM.
europepmc   +3 more sources

Tau expression and phosphorylation in enteroendocrine cells

Frontiers in Neuroscience, 2023
Background and objectiveThere is mounting evidence to suggest that the gut-brain axis is involved in the development of Parkinson’s disease (PD). In this regard, the enteroendocrine cells (EEC), which faces the gut lumen and are connected with both enteric neurons and glial cells have received growing attention.
Chapelet, Guillaume, Béguin, Nora, Castellano, Blandine, Grit, Isabelle, de Coppet, Pierre, Oullier, Thibauld, Neunlist, Michel, Blottière, Hervé, Rolli-Derkinderen, Malvyne, Le Dréan, Gwenola, Derkinderen, Pascal   +10 more
openaire   +6 more sources

Diet: Friend or Foe of Enteroendocrine Cells: How It Interacts with Enteroendocrine Cells [PDF]

Advances in Nutrition, 2012
Gut hormones play a key role in the regulation of food intake, energy expenditure, glucose homeostasis, lipid metabolism, and a wide range of metabolic functions in response to food ingestion. These hormones are altered in metabolic diseases, such as obesity and type 2 diabetes, and are thus proposed to be possible targets for the prevention or ...
Sofia, Moran-Ramos, Armando R, Tovar, Nimbe, Torres   +2 more
openaire   +2 more sources

Enteroendocrine cell differentiation: Implications for human disease. [PDF]

Mol Cell Endocrinol
Enteroendocrine cells are the most abundant hormone producing cells in humans. Though they make up less than 1 % of the gastrointestinal epithelium, these cells have a large physiological impact through the secretion of hormones that act both locally and systemically to regulate intestinal function and whole-body metabolism, among other functions.
Saint-Denis E, Frintu B, Goldsmith M, Ramos GP, Zeve D.   +4 more
europepmc   +3 more sources

Pharmacology and physiology of gastrointestinal enteroendocrine cells [PDF]

Pharmacology Research & Perspectives, 2015
AbstractGastrointestinal (GI) polypeptides are secreted from enteroendocrine cells (EECs). Recent technical advances and the identification of endogenous and synthetic ligands have enabled exploration of the pharmacology and physiology of EECs. Enteroendocrine signaling pathways stimulating hormone secretion involve multiple nutrient transporters and G
Mace, O J, Tehan, B, Marshall, F
openaire   +2 more sources

Nutrition and L and K-enteroendocrine cells [PDF]

Current Opinion in Endocrinology, Diabetes & Obesity, 2011
The review highlights the influence of nutrients over the secretion of several hormones produced by enteroendocrine cells in the gastrointestinal tract that secrete incretin hormones. These hormones influence glucose homeostasis; food intake; gastric, pancreatic and hepatic secretions; and gastric and intestinal motility, and these aspects are ...
Ruth, Gutierrez-Aguilar, Stephen C, Woods   +1 more
openaire   +2 more sources

An enteroendocrine cell-enteric glia connection revealed by 3D electron microscopy.

PLoS ONE, 2014
The enteroendocrine cell is the cornerstone of gastrointestinal chemosensation. In the intestine and colon, this cell is stimulated by nutrients, tastants that elicit the perception of flavor, and bacterial by-products; and in response, the cell secretes
Diego V Bohórquez, Leigh A Samsa, Andrew Roholt, Satish Medicetty, Rashmi Chandra, Rodger A Liddle   +5 more
doaj   +1 more source

Abnormalities in ileal stem, neurogenin 3, and enteroendocrine cells in patients with irritable bowel syndrome

BMC Gastroenterology, 2017
Background This study examined whether the densities of stem- and enteroendocrine cell progenitors are abnormal in the ileum of patients with irritable bowel syndrome (IBS), and whether any abnormalities in ileal enteroendocrine cells are correlated with
Magdy El-Salhy, Odd Helge Gilja
doaj   +1 more source

Non-canonical Wnt signaling promotes directed migration of intestinal stem cells to sites of injury

Nature Communications, 2021
Stem cell migration is critical during adult tissue regeneration. Here, the authors demonstrate that enteroendocrine cells coordinate stem cell migration towards sites of injury in the Drosophila intestine by activating non-canonical Wnt signaling.
Daniel Jun-Kit Hu, Jina Yun, Justin Elstrott, Heinrich Jasper   +3 more
doaj   +1 more source