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High-Resolution mRNA and Secretome Atlas of Human Enteroendocrine Cells [PDF]
Cell, 2020 Enteroendocrine cells (EECs) sense intestinal content and release hormones to regulate gastrointestinal activity, systemic metabolism, and food intake.
Franka H van der Linden +2 more
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Enteroendocrine Cells: Chemosensors in the Intestinal Epithelium
Annual Review of Physiology, 2016The enteroendocrine system orchestrates how the body responds to the ingestion of foods, employing a diversity of hormones to fine-tune a wide range of physiological responses both within and outside the gut. Recent interest in gut hormones has surged with the realization that they modulate glucose tolerance and food intake through a variety of ...
Frank Reimann, Fiona Gribble
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Enteroendocrine cells in the Echinodermata
Cell and Tissue Research, 2019Enteroendocrine cells are endocrine-like cells found in the luminal epithelia of the digestive tract. These cells have been described in most animal phyla. In echinoderms, the cells have been described mainly in organisms of the class Asteroidea (sea stars) and Holothuroidea (sea cucumbers).
José E. García-Arrarás +2 more
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Chemosensing in enteroendocrine cells: mechanisms and therapeutic opportunities
Current Opinion in Endocrinology, Diabetes & Obesity, 2021Purpose of review Enteroendocrine cells (EECs) are scattered chemosensory cells in the intestinal epithelium that release hormones with a wide range of actions on intestinal function, food intake and glucose homeostasis. The mechanisms by which gut hormones are secreted postprandially, or altered by antidiabetic agents and ...
Ming, Yang +2 more
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Review: Enteroendocrine cells: Neglected players in gastrointestinal disorders? [PDF]
Therapeutic Advances in Gastroenterology, 2008 Enteroendocrine cells (EEC) form the basis of the largest endocrine system in the body. They secrete multiple regulatory molecules which control physiological and homeostatic functions, particularly postprandial secretion and motility. Their key purpose is to act as sensors of luminal contents, either in a classical endocrine fashion, or by a ...
John Mclaughlin +2 more
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Enteroendocrine cells in sheep fetuses
Small Ruminant Research, 1991Abstract The appearance and topographic distribution of endocrine cells of the gastro-entero-pancreatic system was investigated in the duodenum, colon and rectum of sheep fetuses at the 13th and 20th week of gestation. Endocrine cells were detected by means of silver impregnation and immunocytochemical techniques using antibodies against serotonin ...
CECCARELLI, Piero +2 more
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[Enteroendocrine cells, their structure and function].
Arkhiv anatomii, gistologii i embriologii, 1985The modern classification of the gastroenteropancreatic endocrine system (GEPES) is presented. Qualitative and quantitative composition of the entero-endocrine system (EES) included in the GEPES is considered, as well as functional role of every type of the cells.
V A, Shakhlamov, V I, Makar'
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Enteroendocrine cell signalling via the vagus nerve
Current Opinion in Pharmacology, 2013Nutrient delivery to the gut activates neuroendocrine mechanisms that control digestion and energy intake and utilisation. These include the release from enteroendocrine cells of mediators including 5HT, CCK, GLP-1, PYY and ghrelin that act on vagal afferent neurons regulating food intake and autonomic reflexes controlling motility, secretion ...
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Function and mechanisms of enteroendocrine cells and gut hormones in metabolism
Nature Reviews Endocrinology, 2019Gut hormones have many key roles in the control of metabolism, as they target diverse tissues involved in the control of intestinal function, insulin secretion, nutrient assimilation and food intake. Produced by scattered cells found along the length of the intestinal epithelium, gut hormones generate signals related to the rate of nutrient absorption,
Fiona M. Gribble, Frank Reimann
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Autotransplantation Modulates Ileal Enteroendocrine Cell Expression in the Pig
Journal of Surgical Research, 2001Enteroendocrine cell-derived peptides modulate postresectional small bowel adaptation, which may be attenuated by transplantation. We investigated whether autotransplantation modulates the number and distribution of ileal enteroendocrine cells in pigs with proximal small bowel resection.Fifteen pigs were assigned into either small intestinal ...
J, Lauronen +4 more
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