Results 21 to 30 of about 491,380 (206)

Screening for Inhibitors of Acetaldehyde Dehydrogenase (AdhE) from Enterohemorrhagic Escherichia coli (EHEC) [PDF]

SLAS Discovery, 2018
Acetaldehyde dehydrogenase (AdhE) is a bifunctional acetaldehyde-coenzyme A (CoA) dehydrogenase and alcohol dehydrogenase involved in anaerobic metabolism in gram-negative bacteria. This enzyme was recently found to be a key regulator of the type three secretion (T3S) system in Escherichia coli.
Zetterström CE, Uusitalo P, Qian W, Hinch S, Caraballo R, Grundström C, Elofsson M   +6 more
openaire   +3 more sources

Extensive genomic diversity and selective conservation of virulence determinants in enterohemorrhagic Escherichia coli strains of O157 and non O157 serotypes [PDF]

, 2007
Background: Enterohemorrhagic Escherichia coli (EHEC) O157 causes severe food-borne illness in humans. The chromosome of O157 consists of 4.1 Mb backbone sequences shared by benign E.
Nougayrède, Jean-Philippe, Tashiro, Kousuke, Ogura, Y, Nakayama, K, Terajima, Jun, Oswald, Eric, Ogura, Yoshitoshi, Tobe, T, Hayashi, T, Ooka, T, Asadulghani, -, Kuhara, Satoru, Watanabe, Haruo, Kurokawa, Ken, Tashiro, K, Watanabe, H, Asadulghani, XX, Ooka, Tadasuke, Kurokawa, K, Nakayama, Keisuke, Hayashi, Tetsuya, Kuhara, S, Tobe, Toru, Terajima, J   +23 more
core   +1 more source

A Robust One-Step Recombineering System for Enterohemorrhagic Escherichia coli

Microorganisms, 2022
Enterohemorrhagic Escherichia coli (EHEC) can cause severe diarrheic in humans. To improve therapy options, a better understanding of EHEC pathogenicity is essential. The genetic manipulation of EHEC with classical one-step methods, such as the transient
Lang Peng, Rexford Mawunyo Dumevi, Marco Chitto, Nadja Haarmann, Petya Berger, Gerald Koudelka, Herbert Schmidt, Alexander Mellmann, Ulrich Dobrindt, Michael Berger   +9 more
doaj   +1 more source

Repetitive N-WASP–binding elements of the Enterohemorrhagic Escherichia coli Effector EspFU Synergistically Activate Actin Assembly [PDF]

, 2008
Enterohemorrhagic Escherichia coli (EHEC) generate F-actin–rich adhesion pedestals by delivering effector proteins into mammalian cells. These effectors include the translocated receptor Tir, along with EspFU, a protein that associates indirectly with ...
McGhie, E.J., Rosen, M.K., Kenneth G Campellone, Robbins, D., Cheng, HC, Robbins, D, Rosen, MK, Koronakis, V, John M Leong, Siripala, AD, Michael K Rosen, Koronakis, V., McGhie Emma J., Leong, JM, Hayward Richard D., Welch, MD, Campellone Kenneth G., Robbins Douglas, Campellone, K.G., Anosha D Siripala, Cheng, H.-C., Leong, J.M., Leong John M., Hui-Chun Cheng, Emma J McGhie, Cheng Hui-Chun, Hayward, RD, Richard D Hayward, Siripala Anosha D., Welch, M.D., Siripala, A.D., Hayward, Richard D., Douglas Robbins, Vassilis Koronakis, Galán, J.E., Campellone, KG, McGhie, EJ, Matthew D Welch, Rosen Michael K., Koronakis Vassilis, Welch Matthew D., Cheng, Hui-Chun, Robbins, Douglas, Siripala, Anosha D., Koronakis, Vassilis, Campellone, Kenneth Geno, Welch, Matthew D., McGhie, Emma J., Rosen, Michael K., Leong, John M.   +49 more
core   +1 more source

Analysis of Collection of Hemolytic Uremic Syndrome–associated Enterohemorrhagic Escherichia coli

Emerging Infectious Diseases, 2008
Multilocus sequence typing of 169 non-O157 enterohemorrhagic Escherichia coli (EHEC) isolated from patients with hemolytic uremic syndrome (HUS) demonstrated 29 different sequence types (STs); 78.1% of these strains clustered in 5 STs.
Alexander Mellmann, Martina Bielaszewska, Robin Köck, Alexander W. Friedrich, Angelika Fruth, Barbara Middendorf, Dag Harmsen, M. Alexander Schmidt, Helge Karch   +8 more
doaj   +1 more source

Sample processing for DNA chip array-based analysis of enterohemorrhagic Escherichia coli (EHEC) [PDF]

Microbial Cell Factories, 2008
Abstract Background Exploitation of DNA-based analyses of microbial pathogens, and especially simultaneous typing of several virulence-related genes in bacteria is becoming an important objective of public health these days.
Basselet, Pascal, Grzegorz Węgrzyn, Sven-Olof Enfors, Magdalena Gabig-Cimińska   +3 more
openaire   +4 more sources

Prevalence and genetic characterization of shiga toxin-producing Escherichia coli isolates from slaughtered animals in Bangladesh [PDF]

, 2008
To determine the prevalence of Shiga toxin (Stx)-producing Escherichia coli (STEC) in slaughter animals in Dhaka, Bangladesh, we collected rectal contents immediately after animals were slaughtered.
Beumer, R.R., Boer, E., de, de Boer, E., Islam, M.A., Talukder, K.A., Zwietering, M.H., Mondol, A.S., Heuvelink, A.E.   +7 more
core   +1 more source

Sequence Variability of P2-Like Prophage Genomes Carrying the Cytolethal Distending Toxin V Operon in Escherichia coli O157 [PDF]

, 2013
Cytolethal distending toxins (CDT) are potent cytotoxins of several Gram-negative pathogenic bacteria, including Escherichia coli, in which five types (CDT-I to CDT-V) have been identified so far.
Dobrindt, Ulrich, Maróti, Gergely, Sváb, Domonkos, Horváth, Balázs, Tóth, István   +4 more
core   +1 more source

L-glutamine protects against enterohemorrhagic Escherichia coli infection by inhibiting bacterial virulence and enhancing host defense concurrently

Microbiology Spectrum, 2023
Enterohemorrhagic Escherichia coli (EHEC) can colonize the gastrointestinal tract and cause bloody diarrhea in children. Previous studies showed that its pathogenesis could be mediated by metabolites from both the host and microbiota.
Fang Fang, Yunxin Xue, Xuefang Xu, Dingli Fang, Weijia Liu, Ying Zhong, Jinping Han, Yunhe Li, Qian Tao, Rong Lu, Cong Ma, Arvind Kumar, Dai Wang   +12 more
doaj   +1 more source

Generation of gene deletions and gene replacements in Escherichia coli O157:H7 using a temperature sensitive allelic exchange system [PDF]

, 2006
In this work we describe protocols for the generation of gene deletions and gene replacements using a temperature sensitive plasmid in Escherichia coli O157:H7.
James R. Emmerson, Emmerson, James R, Roe, Andrew J, David L. Gally, Andrew J. Roe, Roe, A, Gally, David L   +6 more
core   +1 more source