Results 61 to 70 of about 491,380 (206)

The NAG Sensor NagC Regulates LEE Gene Expression and Contributes to Gut Colonization by Escherichia coli O157:H7

Frontiers in Cellular and Infection Microbiology, 2017
Enterohemorrhagic Escherichia coli (EHEC) O157:H7 are human pathogens responsible for bloody diarrhea and renal failures. EHEC employ a type 3 secretion system to attach directly to the human colonic epithelium.
Josée Harel, Grégory Jubelin, Guillaume Le Bihan, Jean-Félix Sicard, Philippe Garneau, Annick Bernalier-Donadille, Alain P. Gobert, Annie Garrivier, Christine Martin, Anthony G. Hay, Francis Beaudry   +10 more
doaj   +1 more source

Ribosome State Distributions Define Escherichia coli Persister Physiology: Links to Formation, Stress Responses, and Resuscitation Dynamics

Microbial Biotechnology, Volume 19, Issue 4, April 2026.
The AUCS70/AUCS100 ratio, derived from ribosome sedimentation profiling, quantitatively distinguishes Escherichia coli persisters from growing cells across multiple stress conditions and identifies RMF as the primary target for anti‐persistence strategies. ABSTRACT Persister cells survive antibiotic exposure and contribute to infection relapse, yet the
Hyein Kim, Sooyeon Song
wiley   +1 more source

Presence of Enterohemorrhagic Escherichia coli ST678/O104:H4 in France Prior to 2011

, 2011
International audienceTwo isolates of enterohemorrhagic Escherichia coli (EHEC) O104:H4 were isolated in France in 2004 and 2009. Both were characterized and compared to the strain which caused the German outbreak in 2011 and to other O104:H4 strains ...
François-Xavier Weill, Balière, Charlotte, Ehricht, Ralf, Ralf Ehricht, Slickers, Peter, Peter Slickers, Charlotte Balière, Mariani-Kurkdjian, Patricia, Stefan Monecke, Bingen, Edouard, Monecke, Stefan, Edouard Bingen, Patricia Mariani-Kurkdjian, Weill, François-Xavier   +13 more
core   +1 more source

Characterisation of the effects of salicylidene acylhydrazide compounds on type three secretion in Escherichia coli O157:H7 [PDF]

, 2009
Recent work has highlighted a number of compounds that target bacterial virulence by affecting gene regulation. In this work, we show that small-molecule inhibitors affect the expression of the type III secretion system (T3SS) of <i>Escherichia ...
Layton, Abigail, Stevens, M. P., Tree, J.J., Stevens, Mark P, Tree, J. J., Roe, A. J., McInally, C., Roe, Andrew J, Tree, Jai J, Wang, Dai, Elofsson, M., Houghton, I., Mahajan, A., Stevens, M.P., Gally, D. L., Roe, A.J., Wang, D., Gally, D.L., Layton, A., Elofsson, Mikael,, McInally, Carol, Houghton, Irene, Mahajan, Arvind, Gally, David L   +23 more
core   +1 more source

Enterohemorrhagic Escherichia coli O157:H7: case report

The Turkish Journal of Pediatrics, 2008
Enterohemorrhagic Escherichia coli (EHEC) is a significant bacterial pathogen of bloody diarrhea. Not only does it cause systemic complications, such as hemolytic uremic syndrome (HUS) (the most common cause of potentially preventable pediatric ...
Haluk Erdoğan, Aşkin Erdoğan, Belkis Levent, Revasiye Kayali, Hande Arslan   +4 more
doaj  

Engineered bacterial therapy suppresses Enterohemorrhagic Escherichia coli through metabolic competition and virulence silencing

Nature Communications
Enterohemorrhagic Escherichia coli (EHEC) is a severe foodborne pathogen that can lead to hemolytic uremic syndrome. However, antibiotics are contraindicated for EHEC treatment due to toxin release and gut microbiota disruption.
Guozhen Ma, Ruiying Liu, Xueping Li, Jialin Wu, Yuanyuan Niu, Sheng Wang, Ziwei Chen, Xudong Qin, Qian Wang, Junyue Wang, Jiamin Qian, Mingqing Zhang, Yu Pang, Yamin Sun, Guosheng Tang, Tao Wang, Yutao Liu   +16 more
doaj   +1 more source

IGLR-2, a Leucine-Rich Repeat Domain Containing Protein, Is Required for the Host Defense in Caenorhabditis elegans

Frontiers in Immunology, 2020
Enterohemorrhagic Escherichia coli (EHEC), a human pathogen, also infects Caenorhabditis elegans. We demonstrated previously that C. elegans activates the p38 MAPK innate immune pathway to defend against EHEC infection. However, whether a C.
Cheng-Ju Kuo, Cheng-Ju Kuo, Ya-Chu Hsu, Sin-Tian Wang, Bang-Yu Liou, Serene Boon-Yuean Lim, Yi-Wei Chen, Chang-Shi Chen, Chang-Shi Chen   +8 more
doaj   +1 more source

Engineered Probiotics: The Next‐Generation Therapeutics to Combat Antibiotic‐Resistant Bacterial Infections

Food Frontiers, Volume 7, Issue 2, March 2026.
Engineered probiotics secretes fusion proteins which potentially neutralized the toxins secreted by other microbial communities. ABSTRACT On a global scale, the escalating burden of infectious diseases, predominantly attributed to bacterial pathogens, especially drug‐resistant strains, has progressed into a critical concern for clinical management and ...
Indu Singh, Raz Abdulqadir, Indira Kumari Verma, Yashika Awasthi, Arun Ratn, Juhi Sharma, Manmeet Rawat, Megh Singh Dhakad, Jasbir Dalal, Yash Gupta, Bhisham Narayan Singh, Divakar Sharma   +11 more
wiley   +1 more source

Enterococcus faecalis Enhances Expression and Activity of the Enterohemorrhagic Escherichia coli Type III Secretion System

mBio, 2019
The gut microbiota can significantly impact invading pathogens and the disease they cause; however, many of the mechanisms that dictate commensal-pathogen interactions remain unclear.
Elizabeth A. Cameron, Vanessa Sperandio, Gary M. Dunny   +2 more
doaj   +1 more source

Intimate Attachment of Escherichia coli O157:H7 to Urinary Bladder Epithelium in the Gnotobiotic Piglet Model

Microorganisms, 2020
Enterohemorrhagic Escherichia coli (EHEC), a pathogenic subset of Shiga toxin-producing E. coli (STEC), is an important cause of hemorrhagic colitis and hemolytic−uremic syndrome (HUS), and a rare cause of urinary tract infections (UTIs) with ...
Rodney A. Moxley, Tom W. Bargar, Stephen D. Kachman, Diane R. Baker, David H. Francis   +4 more
doaj   +1 more source