Results 91 to 100 of about 32,465 (166)

The Metabolic Nexus of Indigenous Health Disparities: Exploring the Intersecting Roles of Enterotoxigenic Bacteroides fragilis (ETBF), Thiamine, and Niacin

Title The Metabolic Nexus of Indigenous Health Disparities: Exploring the Intersecting Roles of Enterotoxigenic Bacteroides fragilis (ETBF), Thiamine, and Niacin   Description / Abstract This position paper outlines a novel, unified biochemical paradigm to explain the persistent disparities in acute and chronic disease burdens between First ...
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Modeling ETBF-Mediated Colorectal Tumorigenesis Using AOM/DSS in Wild-Type Mice

Enterotoxigenic Bacteroides fragilis (ETBF) promotes colitis-associated cancer through the Bacteroides fragilis toxin (BFT), which induces colonic inflammation that can be exacerbated by external stimuli.
Yeram Lee, Soonjae Hwang, Ki-Jong Rhee
core   +1 more source

Virulence of Enterotoxigenic Bacteroides Fragilis (ETBF) Strains is B. Fragilis Toxin (BFT) Isoform Dependent

Gastroenterology, 2011
Shaoguang Wu, Kenolisa Onwueme, XinQun Wu, Guillermo Ortega, Augusto Franco-Mora, Franck Housseau, Drew M. Pardoll, Cynthia L. Sears   +7 more
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An enteropathogenic microbial toxin modulates the breast cancer epigenome resulting in concurrent silencing of tumor suppressor genes

Breast Cancer Research
Background Recent studies have determined a close association between host microbiota and breast cancer initiation, growth and therapeutic outcomes.
Deepak Verma, Deeptashree Nandi, Sheetal Parida, Archisha Saxena, Dipali Sharma   +4 more
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Keystone pathobionts associated with colorectal cancer promote oncogenic reprograming.

PLoS ONE
Fusobacterium nucleatum (Fn) and enterotoxigenic Bacteroides fragilis (ETBF) are two pathobionts consistently enriched in the gut microbiomes of patients with colorectal cancer (CRC) compared to healthy counterparts and frequently observed for their ...
Josh Jones, Qiaojuan Shi, Rahul R Nath, Ilana L Brito   +3 more
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Enterotoxigenic Bacteroides fragilis (ETBF)-mediated colitis in Min ( Apc ^+/- ) mice: a human commensal-based murine model of colon carcinogenesis [PDF]

Cell Cycle, 2010
Franck, Housseau, Cynthia L, Sears
openaire   +2 more sources

Evaluation of the prevalence of enterotoxigenic Bacteroides fragilis and the distribution bft gene subtypes in patients with diarrhea

, 2010
The aim of this study was to determine the prevalence of enterotoxigenic Bacteroides fragilis (ETBF) in the patients with diarrhea in our region and to assess the association between diarrhea and bft gene subtypes.
Füsun Cömert, Mehtap Akpınar, Vildan Sümbüloğlu, Canan Külah, Elif Aktaş   +4 more
core   +1 more source

Gut microbiota and colorectal cancer: mechanistic insights, diagnostic advances, and microbiome-based therapeutic strategies

Frontiers in Microbiology
Colorectal cancer (CRC) is closely linked to gut microbiota dysbiosis. We synthesize evidence that carcinogenic microbes promote CRC through chronic inflammation, bacterial genotoxins, and metabolic imbalance, highlighting key pathways involving ...
Bingbing Bai, Bingbing Bai, Bingbing Bai, Bingbing Bai, Jianing Ma, Jianing Ma, Jianing Ma, Jianing Ma, Wenlong Xu, Wenlong Xu, Wenlong Xu, Wenlong Xu, Xiaomin Chen, Xiaomin Chen, Xiaomin Chen, Xiaomin Chen, Xu Chen, Xu Chen, Xu Chen, Xu Chen, Chao Lv, Chao Lv, Chao Lv, Chao Lv, Wei Su, Wei Su, Wei Su, Wei Su, Yaoxu Li, Yaoxu Li, Yaoxu Li, Yaoxu Li, Hongyin Sun, Hongyin Sun, Hongyin Sun, Hongyin Sun, Baoyin Zhang, Baoyin Zhang, Baoyin Zhang, Baoyin Zhang, Dejuan Xiang, Dejuan Xiang, Dejuan Xiang, Dejuan Xiang, Zhongsha Li, Zhongsha Li, Zhongsha Li, Zhongsha Li, Yuesong Wu, Yuesong Wu, Yuesong Wu, Yuesong Wu, Jian Sun, Jian Sun, Jian Sun, Jian Sun, Mingzhu Yin, Mingzhu Yin, Mingzhu Yin, Mingzhu Yin   +59 more
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The Fragilysin-Induced Epithelial-Allergic Axis: How Enterotoxigenic Bacteroides fragilis (ETBF) Derails Oral Tolerance, and the Therapeutic Potential of Niacin/NAD+ Intervention

Title The Fragilysin-Induced Epithelial-Allergic Axis: How Enterotoxigenic Bacteroides fragilis (ETBF) Derails Oral Tolerance, and the Therapeutic Potential of Niacin/NAD+ Intervention   Description   Abstract This manuscript introduces a novel, multidisciplinary mechanistic framework bridging microbiome pathogenesis, mucosal immunology, and ...
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The ETBF-Endocrine Respiration Loop: How Living Enterotoxigenic Bacteroides fragilis Exploits Host Steroid Shunts to Drive Pseudohypoxia, Field Cancerization, and Endocrine Therapy Resistance

The ETBF-Endocrine Respiration Loop: How Living Enterotoxigenic Bacteroides fragilis Exploits Host Steroid Shunts to Drive Pseudohypoxia, Field Cancerization, and Endocrine Therapy Resistance   Description / Abstract Field: This paper presents a groundbreaking, closed-loop translational model of microbial endocrinology that redefines our ...
openaire   +2 more sources