Results 1 to 10 of about 94 (65)

A Systemic Review of the Role of Enterotoxic Bacteroides fragilis in Colorectal Cancer

Neoplasia, 2022
Enterotoxigenic Bacteroides fragilis (ETBF) has received significant attention for a possible association with, or causal role in, colorectal cancer (CRC).
Nicholas Chia, Patricio Jeraldo, Nancy E Scott   +2 more
exaly   +3 more sources

Colon Tumors in Enterotoxigenic Bacteroides fragilis (ETBF)-Colonized Mice Do Not Display a Unique Mutational Signature but Instead Possess Host-Dependent Alterations in the APC Gene.

Microbiology Spectrum, 2022
Enterotoxigenic Bacteroides fragilis (ETBF) is consistently found at higher frequency in individuals with sporadic and hereditary colorectal cancer (CRC) and induces tumorigenesis in several mouse models of CRC.
Heather O'Hagan, Hans Clevers, Shaoguang Wu   +2 more
exaly   +3 more sources

Enterotoxigenic Bacteroides fragilis: A Possible Etiological Candidate for Bacterially-Induced Colorectal Precancerous and Cancerous Lesions

Frontiers in Cellular and Infection Microbiology, 2020
Enterotoxigenic Bacteroides fragilis (ETBF) produces Bacteroides fragilis toxin (BFT), which is associated with acute diarrheal, inflammatory bowel disease, and colorectal cancer (CRC).
Samin Zamani, Seyedesomaye Jasemi
exaly   +3 more sources

Carbapenem Resistance in Enterotoxigenic Bacteroides fragilis Isolated From Colonoscopy Candidates

AMB Express
The present study aimed to determine the carbapenem resistance among Enterotoxigenic Bacteroides fragilis (ETBF) isolated from patients candidates to colonoscopy in Shiraz, Iran. A total of 201 stool samples were gathered from 201 patients. The detection
Taher Azimi
exaly   +2 more sources

Quantitative Profiling of Colorectal Cancer-Associated Bacteria Reveals Associations Between Fusobacterium spp., Enterotoxigenic Bacteroides fragilis (ETBF) and Clinicopathological Features of Colorectal Cancer

PLoS ONE, 2015
Various studies have presented clinical or in vitro evidence linking bacteria to colorectal cancer, but these bacteria have not previously been concurrently quantified by qPCR in a single cohort.
Jonathan Blackburn, Katie S Viljoen
exaly   +2 more sources

Case-control study on the role of enterotoxigenic Bacteroides fragilis as a cause of diarrhea among children in Kolkata, India. [PDF]

PLoS ONE, 2013
A total of 874 fecal specimens (446 diarrheal cases and 428 controls) from diarrheal children admitted in the Infectious Diseases Hospital, Kolkata and age and sex matched asymptomatic subjects from an urban community were assessed for the prevalence of ...
Dharanidharan Ramamurthy, Gururaja P Pazhani, Anirban Sarkar, Ranjan K Nandy, Krishnan Rajendran, Dipika Sur, Bamkesh Manna, Thandavarayan Ramamurthy   +7 more
doaj   +1 more source

Enterotoxigenic Bacteroides fragilis activates IL-8 expression through Stat3 in colorectal cancer cells

Gut Pathogens, 2022
Background Enterotoxigenic Bacteroides fragilis (ETBF) has been implicated in colorectal carcinogenesis through the actions of its toxin, B. fragilis toxin (BFT).
Rachel V. Purcell, Jessica Permain, Jacqueline I. Keenan   +2 more
doaj   +1 more source

G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis

Communications Biology, 2021
Boleij et al. show that G protein-coupled receptor 35 (GPR35) regulates the responses to enterotoxigenic Bacteroides fragilis (ETBF) in colonic epithelial cells.
Annemarie Boleij, Payam Fathi, William Dalton, Ben Park, Xinqun Wu, David Huso, Jawara Allen, Sepideh Besharati, Robert A. Anders, Franck Housseau, Amanda E. Mackenzie, Laura Jenkins, Graeme. Milligan, Shaoguang Wu, Cynthia L. Sears   +14 more
doaj   +1 more source

Genomic Diversity of Enterotoxigenic Strains of Bacteroides fragilis. [PDF]

PLoS ONE, 2016
Enterotoxigenic (ETBF) strains of Bacteroides fragilis are the subset of strains that secrete a toxin called fragilysin (Bft). Although ETBF strains are known to cause diarrheal disease and have recently been associated with colorectal cancer, they have ...
Jessica V Pierce, Harris D Bernstein
doaj   +1 more source

Enterotoxigenic Bacteroides fragilis induces the stemness in colorectal cancer via upregulating histone demethylase JMJD2B

Gut Microbes, 2020
The enrichment of Enterotoxigenic Bacteroides fragilis (ETBF) has been identified in CRC patients and associated with worse prognosis. Cancer stem cells (CSCs) play essential roles in CRC development.
Qian-Qian Liu, Chun-Min Li, Lin-Na Fu, Hao-Lian Wang, Juan Tan, Yun-Qian Wang, Dan-Feng Sun, Qin-Yan Gao, Ying-Xuan Chen, Jing-Yuan Fang   +9 more
doaj   +1 more source