Results 31 to 40 of about 110,587 (280)

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Enterovirus RNA in peripheral blood may be associated with the variants of rs1990760, a common type 1 diabetes associated polymorphism in IFIH1. [PDF]

PLoS ONE, 2012
Polymorphisms in the IFIH1 (common rs1990760 and four rare rs35667974, rs35337543, rs35744605, rs35732034) have been convincingly associated with type 1 diabetes.
Ondrej Cinek, German Tapia, Elisabet Witsø, Lenka Kramna, Katerina Holkova, Trond Rasmussen, Lars C Stene, Kjersti S Rønningen   +7 more
doaj   +1 more source

Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus. [PDF]

, 2017
The present study examines the susceptibility of mouse induced pluripotent stem cell-derived neural precursor cells (iPSC-NPCs) to infection with the neurotropic JHM strain of mouse hepatitis virus (JHMV).
Lane, Thomas E, Mangale, Vrushali, Marro, Brett S, Plaisted, Warren C, Walsh, Craig M   +4 more
core   +1 more source

Alteration in CD8+ T cell subsets in enterovirus-infected patients: An alarming factor for type 1 diabetes mellitus [PDF]

, 2018
Type 1 diabetes is a multi-factorial disease that can develop due to the combination of genetic and environmental factors. Viruses, particularly enteroviruses, are major environmental candidates in the pathogenesis of type 1 diabetes, even though the ...
Ghatrehsamani, Mahdi, Izad, Maryam, Jamshidian, A. R., Kheiri, Soleiman, Mahmoodnia, Lila, Sadeghian, Ladan, Sarmadi, Akram, Shirzad, Hedayatollah, Soltani, Amin, Zargari Samani, Omid   +9 more
core   +4 more sources

Research progress on the quality control of mRNA vaccines

Expert Review of Vaccines
Introduction The mRNA vaccine technologies have progressed rapidly in recent years. The COVID-19 pandemic has accelerated the application of mRNA vaccines, with research and development and clinical trials underway for many vaccines.
Chaoying Hu, Yu Bai, Jianyang Liu, Yiping Wang, Qian He, Xuanxuan Zhang, Feiran Cheng, Miao Xu, Qunying Mao, Zhenglun Liang   +9 more
doaj   +1 more source

Enterovirus infection in the Socialist Republic of Vietnam

Инфекция и иммунитет, 2019
Human enterovirus infections comprise a group of infectious diseases caused by viruses of Enterovirus A-D species (genus Enterovirus, family Picornaviridae).
L. N. Golitsyna, T. T.T. Nguyen, N. I. Romanenkova, M. T. Luong, L. T. Vu, O. I. Kanaeva, M. A. Bichurina, N. A. Novikova   +7 more
doaj   +1 more source

The TLR3/IRF1/Type III IFN Axis Facilitates Antiviral Responses against Enterovirus Infections in the Intestine

mBio, 2020
Enteroviruses infect gastrointestinal epithelium cells, cause multiple human diseases, and present public health risks worldwide. However, the mechanisms underlying host immune responses in intestinal mucosa against the early enterovirus infections ...
Rui Su, Muhammad Adnan Shereen, Xiaofeng Zeng, Yicong Liang, Wen Li, Zhihui Ruan, Yongkui Li, Weiyong Liu, Yingle Liu, Kailang Wu, Zhen Luo, Jianguo Wu   +11 more
doaj   +1 more source

Non-small cell lung cancers (NSCLCs) oncolysis using coxsackievirus B5 and synergistic DNA-damage response inhibitors

Signal Transduction and Targeted Therapy, 2023
With the continuous in-depth study of the interaction mechanism between viruses and hosts, the virus has become a promising tool in cancer treatment.
Bopei Cui, Lifang Song, Qian Wang, Kelei Li, Qian He, Xing Wu, Fan Gao, Mingchen Liu, Chaoqiang An, Qiushuang Gao, Chaoying Hu, Xiaotian Hao, Fangyu Dong, Jiuyue Zhou, Dong Liu, Ziyang Song, Xujia Yan, Jialu Zhang, Yu Bai, Qunying Mao, Xiaoming Yang, Zhenglun Liang   +21 more
doaj   +1 more source

Human Enterovirus B: Selective Inhibition by Quinoxaline Derivatives and Bioinformatic RNA-Motif Identification as New Targets

Pharmaceuticals, 2022
The Enterovirus genus includes many viruses that are pathogenic in humans, including Coxsackie viruses and rhinoviruses, as well as the emerging enteroviruses D68 and A71.
Silvia Madeddu, Roberta Ibba, Giuseppina Sanna, Sandra Piras, Federico Riu, Alessandra Marongiu, Annalisa Ambrosino, Paola Caria, Valentina Onnis, Gianluigi Franci, Aldo Manzin, Antonio Carta   +11 more
doaj   +1 more source

Deficiency of immunity to poliovirus type 3: a lurking danger? [PDF]

, 2012
Background: Europe was certified to be polio-free in 2002 by the WHO. However, wild polioviruses remain endemic in India, Pakistan, Afghanistan, and Nigeria, occasionally causing polio outbreaks, as in Tajikistan in 2010.
Doerr, Hans W., Friedrichs, Imke, Rabenau, Holger, Reinheimer, Claudia   +3 more
core   +2 more sources