Results 21 to 30 of about 88,811 (243)

Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron

open access: yesAngewandte Chemie, EarlyView.
Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej   +20 more
wiley   +2 more sources

Enterovirus inactivation in soil [PDF]

open access: yesApplied and Environmental Microbiology, 1979
The inactivation of radioactively labeled poliovirus type 1 and coxsackievirus B 1 in soils saturated with surface water, groundwater, and septic tank liquor was directly proportional to temperature. Virus persistence was also related to soil type and the liquid amendment in which viruses were suspended.
J G, Yeager, R T, O'Brien
openaire   +2 more sources

Non-small cell lung cancers (NSCLCs) oncolysis using coxsackievirus B5 and synergistic DNA-damage response inhibitors

open access: yesSignal Transduction and Targeted Therapy, 2023
With the continuous in-depth study of the interaction mechanism between viruses and hosts, the virus has become a promising tool in cancer treatment.
Bopei Cui   +21 more
doaj   +1 more source

Retrospective Surveillance of Wastewater To Examine Seasonal Dynamics of Enterovirus Infections

open access: yesmSphere, 2017
Enteroviruses are RNA viruses that are responsible for both mild gastroenteritis and mild respiratory illnesses as well as debilitating diseases such as meningitis and myocarditis.
Nichole E. Brinkman   +2 more
doaj   +1 more source

A Bayesian Model for Estimation of Virus Reduction in Potable Reuse Treatment Trains and Quantitative Microbial Risk Assessment of Waterborne Viral Pathogens. [PDF]

open access: yesRisk Anal
ABSTRACT Understanding virus occurrence and reduction at advanced treatment facilities for potable water reuse constitutes a high‐priority research need to protect human health and to enhance available water supply alternatives. The objectives were to (1) determine log reduction values (LRVs) of 15 viruses by advanced wastewater treatment; (2) evaluate
Schijven JF, Teunis PFM, Betancourt WQ.
europepmc   +2 more sources

The TLR3/IRF1/Type III IFN Axis Facilitates Antiviral Responses against Enterovirus Infections in the Intestine

open access: yesmBio, 2020
Enteroviruses infect gastrointestinal epithelium cells, cause multiple human diseases, and present public health risks worldwide. However, the mechanisms underlying host immune responses in intestinal mucosa against the early enterovirus infections ...
Rui Su   +11 more
doaj   +1 more source

Research progress on the quality control of mRNA vaccines

open access: yesExpert Review of Vaccines
Introduction The mRNA vaccine technologies have progressed rapidly in recent years. The COVID-19 pandemic has accelerated the application of mRNA vaccines, with research and development and clinical trials underway for many vaccines.
Chaoying Hu   +9 more
doaj   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

open access: yesXenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Attention-Deficit/Hyperactivity-Related Symptoms among Children with Enterovirus 71 Infection of the Central Nervous System

open access: yes, 2009
BACKGROUND. No study has investigated the association between enterovirus 71 central nervous system infection and symptoms related to attention- deficit/hyperactivity disorder .
GAU, SUSAN SHUR-FEN;CHANG, LUAN-YIN;HUANG, LI-MIN;WU, YU-YU;LIN, TZOU-YIEN   +1 more
core   +1 more source

Enterovirus infection in the Socialist Republic of Vietnam

open access: yesИнфекция и иммунитет, 2019
Human enterovirus infections comprise a group of infectious diseases caused by viruses of Enterovirus A-D species (genus Enterovirus, family Picornaviridae).
L. N. Golitsyna   +7 more
doaj   +1 more source

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