Results 31 to 40 of about 74,838 (156)
Advanced Science, EarlyView.This study reports D34 as the first PROTAC degrader that targets the 3C protease of picornaviruses. D34 effectively degrades EV71 3C protease via the ubiquitin‐proteasome pathway. More importantly, D34 exhibits a high resistance barrier and shows broad‐spectrum antiviral activity against multiple picornaviruses, highlighting its potential as a novel ...
Weilong Deng +9 more
wiley +1 more source
Scientific ReportsIn July 2022, an unvaccinated young adult living in Rockland County, New York became paralyzed due to a vaccine-derived poliovirus type 2 (VDPV2) infection that was internationally transmitted. Wastewater surveillance in New York State uncovered VDPV2 in
Grace E. Seo +15 more
doaj +1 more source
Coxsackievirus A21, Enterovirus 68, and Acute Respiratory Tract Infection, China
Emerging Infectious Diseases, 2012 During August 2006–April 2010, in Beijing, China, 2 rare human enterovirus serotypes, coxsackievirus A21 and enterovirus 68, were detected most frequently in human enterovirus–positive adults with acute respiratory tract infections.
Zichun Xiang +10 more
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A Case of Multiple Mitochondrial Dysfunctions Syndrome 1 and Review of the Literature
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Multiple mitochondrial dysfunctions syndrome 1 (MMDS1, MIM #605711) due to NFU1 gene defects is an ultra‐rare autosomal recessive inborn error of metabolism associated with reduced function of NFU1 iron–sulfur cluster (ISC) scaffold protein.
Charles R. DiFalco +6 more
wiley +1 more source
Global Prevalence of Non-Polio Enteroviruses Pre- and Post COVID-19 Pandemic
MicroorganismsNon-polio enteroviruses continue to cause numerous epidemics world-wide that range from mild to severe disease, including acute flaccid paralysis, meningitis, severe respiratory infections and encephalitis.
Marli Vlok, Anna Majer
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Журнал инфектологии, 2017 Aim: Characteristics of the peculiarities and the etiological factor of enterovirus infection on some territories of Russia in 2016. Materials and methods: We investigated 2138 samples from the patients with enterovirus infection.
N. I. Romanenkova +9 more
doaj +1 more source
Viruses, 2023 Outbreaks of hand, foot and mouth disease (HFMD) have occurred frequently in the Asian-Pacific region over the last two decades, caused mainly by the serotypes in Enterovirus A species.
Lie Fu +11 more
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Animal Models and Experimental Medicine, EarlyView.This review summarizes the principal experimental approaches used to induce diabetes in animal models. Strategies include chemical agents (streptozotocin, alloxan, dithizone, gold thioglucose), dietary interventions (high‐fat and high‐sugar diets), surgical methods (total or partial pancreatectomy), genetic models (db/db, ob/ob, Goto‐Kakizaki [GK ...
Milad Faraji +2 more
wiley +1 more source
Detection of anti-enterovirus IgG in human sera by ELISA method using the KTL-510 peptide
Acta VirologicaEnterovirus (EV) infections occur frequently in humans. In some geographical areas they are more common. These viruses cause diseases with varying degrees of severity, from a simple respiratory tract infection to severe diseases.
Michaela Pellerova +10 more
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Журнал микробиологии, эпидемиологии и иммунобиологии, 2018 Aim. To characterize the epidemic situation and the clinical course of enterovirus (neolio) infections in the Krasnodar Territory. Materials and methods. Retrospective analysis of manifestations of the epidemic process and clinical characteristics of non-
L. I. Zhukova +3 more
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