Results 41 to 50 of about 28,174 (173)

Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors

FlexMat, EarlyView.
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu, Yubing Hu, Dong Wang, Ben Zhong Tang   +3 more
wiley   +1 more source

Accuracy of Diagnostic Methods and Surveillance Sensitivity for Human Enterovirus, South Korea, 1999–2011

Emerging Infectious Diseases, 2013
The epidemiology of enteroviral infection in South Korea during 1999–2011 chronicles nationwide outbreaks and changing detection and subtyping methods used over the 13-year period.
Ji-Yeon Hyeon, Seoyeon Hwang, Hyejin Kim, Jaehyoung Song, Jeongbae Ahn, Byunghak Kang, Kisoon Kim, Wooyoung Choi, Jae Keun Chung, Cheon-Hyun Kim, Kyungsoon Cho, Youngmee Jee, Jonghyun Kim, Kisang Kim, Sun-Hee Kim, Min-Ji Kim, Doo-Sung Cheon   +16 more
doaj   +1 more source

The TLR3/IRF1/Type III IFN Axis Facilitates Antiviral Responses against Enterovirus Infections in the Intestine

mBio, 2020
Enteroviruses infect gastrointestinal epithelium cells, cause multiple human diseases, and present public health risks worldwide. However, the mechanisms underlying host immune responses in intestinal mucosa against the early enterovirus infections ...
Rui Su, Muhammad Adnan Shereen, Xiaofeng Zeng, Yicong Liang, Wen Li, Zhihui Ruan, Yongkui Li, Weiyong Liu, Yingle Liu, Kailang Wu, Zhen Luo, Jianguo Wu   +11 more
doaj   +1 more source

Sophocarpine against enterovirus 71 in vitro

Experimental and Therapeutic Medicine, 2017
Sophocarpine (SCA) is a bioactive alkaloid present in Sophoraflavescens Ait. The present study demonstrated that SCA inhibited enterovirus 71 (EV71) infection in Vero cells. The results indicated that the 50% cytotoxicity concentration of SCA for Vero cells was 1,346 µg/ml, and the 50% inhibition concentration of SCA against EV71 was 350 µg/ml.
Zengjun, Jin, Lixin, Yang, Guotao, Ding, Guoxing, Yang, Yonghong, Han, Xia, Zhang, Weihao, Li   +6 more
openaire   +3 more sources

Hand, Foot and Mouth Disease Complicated with Central Nervous System Involvement in Taiwan in 1980–1981

Journal of the Formosan Medical Association, 2007
Sixteen cases from the 1980-1981 Taiwan outbreak of hand, foot and mouth disease (HFMD) associated with central nervous system involvement were identified: nine had polio-like syndrome, four had encephalitis or encephalomyelitis, one had cerebellitis ...
Luan-Yin Chang, Chin-Yun Lee, Chuan-Liang Kao, Tsui-Yen Fang, Chun-Yi Lu, Ping-Ing Lee, Li-Min Huang   +6 more
doaj   +1 more source

Enterovirus infections in children

Pediatric Investigation, EarlyView.
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen, Lingyun Guo, Xiaobo Lei, Linqing Zhao, Mingyan Hei, Jun Shen, Ju Yin, Fei Li, Jikui Deng, Gang Liu, Yong Zhang, Zhengde Xie   +11 more
wiley   +1 more source

Genetic basis of Asian diabetes

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Recent genomic studies in Asian populations have advanced our understanding of the diagnosis, pathophysiology, risk prediction, and precision care of diabetes. Monogenic diabetes, including maturity‐onset diabetes of the young (MODY) and mitochondrial diabetes, highlights the importance of genetic diagnosis for subtype‐specific care.
Takafumi Ojima, Toshimasa Yamauchi
wiley   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Anti-Enterovirus 71 Agents of Natural Products

Molecules, 2015
This review, with 42 references, presents the fascinating area of anti-enterovirus 71 natural products over the last three decades for the first time. It covers literature published from 2005–2015 and refers to compounds isolated from biogenic sources ...
Liyan Wang, Junfeng Wang, Lishu Wang, Shurong Ma, Yonghong Liu   +4 more
doaj   +1 more source

Trained Immunity in Childhood Vaccination

Acta Paediatrica, Volume 115, Issue 11, Page 2402-2413, November 2026.
Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai, Lubnaa Hossenbaccus, Eva Kaufmann   +2 more
wiley   +1 more source