Results 31 to 40 of about 28,174 (173)
Enterovirus and Coxsackievirus are the major viruses that cause hand, foot, and mouth disease (HFMD) outbreaks worldwide. Several studies have shown the potential of viral envelope protein 1 (VP1) on providing protective effects from viral strains of ...
Fang-Hong Chen +12 more
doaj +1 more source
Neurologic Complications of Enterovirus 71 Infection
The neurologic complications associated with the 1998 Taiwan enterovirus 71 epidemic are reported from National Cheng Kung University, Tainan; Chang Gung Children’s Hospital, Kaohsiung; and National Defense Medical Center, Taipei, Taiwan.
J Gordon Millichap
doaj +1 more source
Enterovirus 71 CNS Infection and ADHD
ADHD symptoms as long-term sequelae of virus-confirmed enterovirus 71 infection were evaluated in 86 children, aged 4 to 16 years, followed at National Taiwan University Hospital, Taipei, and Chang Gung Children’s Hospital, Taoyuan, Taiwan.
J Gordon Millichap
doaj +1 more source
Crystal Structure of Human Enterovirus 71 [PDF]
The structure of a virus linked to neurological disease reveals how drugs targeting viruses in this family can be modified.
Pavel, Plevka +4 more
openaire +2 more sources
This study reports D34 as the first PROTAC degrader that targets the 3C protease of picornaviruses. D34 effectively degrades EV71 3C protease via the ubiquitin‐proteasome pathway. More importantly, D34 exhibits a high resistance barrier and shows broad‐spectrum antiviral activity against multiple picornaviruses, highlighting its potential as a novel ...
Weilong Deng +9 more
wiley +1 more source
Excellent Response to Plasma Exchange in Three Patients With Enterovirus-71 Neurological Disease
The clinical spectrum of Enterovirus-71-associated neurological disease includes acute flaccid paralysis, encephalomyelitis, or brainstem encephalitis with autonomic dysfunction.
Elba Pascual-Goñi +8 more
doaj +1 more source
The infection mechanism of enterovirus 71
Identification of a specific viral receptor is important for understanding the virus infection mechanism. I identified P-selectin glycoprotein ligand-1 (PSGL-1) as one of the functional receptors for enterovirus 71 (EV71), a pathogen that causes hand, foot, and mouth disease.
openaire +3 more sources
Host Factors in Enterovirus 71 Replication [PDF]
ABSTRACT Enterovirus 71 (EV71) infections continue to remain an important public health problem around the world, especially in the Asia-Pacific region. There is a significant mortality rate following such infections, and there is neither any proven therapy nor a vaccine for EV71.
Shin-Ru, Shih +2 more
openaire +2 more sources
First isolation of enterovirus 71 (EV-71) from Northern Brazil
Enterovirus 71 (EV-71) has been associated to cases of neurological disease in many countries including Brazil. This virus has now been reported from three of the five Brazilian regions.
Leticia Martins Lamarão +2 more
doaj +1 more source
Introduction Fulminant cardiopulmonary failure is a severe complication of hand, foot and mouth diseases due to enterovirus 71 infection, with a high mortality rate. The treatment is mainly supportive with aggressive cardiopulmonary resuscitation.
Phan Phuc +6 more
doaj +1 more source

