Results 11 to 20 of about 28,174 (173)

Enterovirus 71 Virus Propagation and Purification [PDF]

open access: yesBio-Protocol, 2014
Since its discovery in 1969, enterovirus 71 (EV71) has emerged as a serious worldwide health threat. This member of the picornavirus family causes hand, foot, and mouth disease, and also has the capacity to invade the central nervous system to cause ...
Kristin Shingler   +2 more
doaj   +3 more sources

COPI is required for enterovirus 71 replication. [PDF]

open access: yesPLoS ONE, 2012
Enterovirus 71 (EV71), a member of the Picornaviridae family, is found in Asian countries where it causes a wide range of human diseases. No effective therapy is available for the treatment of these infections.
Jianmin Wang, Zhiqiang Wu, Qi Jin
doaj   +4 more sources

Seroepidemiology of Human Enterovirus 71, Singapore

open access: yesEmerging Infectious Diseases, 2002
Human enterovirus 71 has caused outbreaks in many parts of the world, especially Southeast Asia, with some fatal cases. The epidemiology of this viral infection is not well understood.
Eng-Eong Ooi   +3 more
doaj   +3 more sources

Challenges to licensure of enterovirus 71 vaccines.

open access: yesPLoS Neglected Tropical Diseases, 2012
Human enteroviruses usually cause self-limited infections except polioviruses and enterovirus 71 (EV71), which frequently involve neurological complications. EV71 vaccines are being evaluated in humans.
Min-Shi Lee   +5 more
doaj   +3 more sources

Neonates with acute liver failure have higher overall mortality but similar posttransplant outcomes as older infants

open access: yesLiver Transplantation, EarlyView., 2022
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala   +6 more
wiley   +1 more source

The cellular receptor for enterovirus 71 [PDF]

open access: yesProtein & Cell, 2014
The Picornaviridae family consists of a large group of non-enveloped, icosahedral viruses with a single, positive-stranded RNA genome. The family includes pathogens that are notable for a variety of human and animal diseases (Racaniello, 2007). Picornaviruses initiate infections by attachment to host cell receptor molecules and then undergo uncoating ...
Liu, Yue, Rossmann, Michael G.
openaire   +2 more sources

Structure determination of enterovirus 71 [PDF]

open access: yesActa Crystallographica Section D Biological Crystallography, 2012
Enterovirus 71 is a picornavirus that causes hand, foot and mouth disease but may induce fatal neurological illness in infants and young children. Enterovirus 71 crystallized in a body-centered orthorhombic space group with two particles in general orientations in the crystallographic asymmetric unit. Determination of the particle orientations required
Pavel, Plevka   +4 more
openaire   +2 more sources

Review of Enterovirus 71 Vaccines [PDF]

open access: yesClinical Infectious Diseases, 2014
Enterovirus 71 (EV71) and coxsackieviruses are the major causative agents of hand, foot, and mouth disease (HFMD) outbreaks worldwide and have a significant socioeconomic impact, particularly in Asia. Formalin-inactivated (FI) EV71 vaccines evaluated in human clinical trials in China, Taiwan, and Singapore were found to be safe and to elicit strong ...
Pele, Chong   +4 more
openaire   +2 more sources

Evidence of enterovirus 71 infections in Brazil [PDF]

open access: yesMemorias do Instituto Oswaldo Cruz, 1990
Edson E. da Silva   +3 more
doaj   +4 more sources

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