Results 51 to 60 of about 44,110 (248)
Excellent Response to Plasma Exchange in Three Patients With Enterovirus-71 Neurological Disease
Frontiers in Neurology, 2019 The clinical spectrum of Enterovirus-71-associated neurological disease includes acute flaccid paralysis, encephalomyelitis, or brainstem encephalitis with autonomic dysfunction.
Elba Pascual-Goñi +8 more
doaj +1 more source
mBio, 2020 Enteroviruses infect gastrointestinal epithelium cells, cause multiple human diseases, and present public health risks worldwide. However, the mechanisms underlying host immune responses in intestinal mucosa against the early enterovirus infections ...
Rui Su +11 more
doaj +1 more source
Interdisciplinary Medicine, EarlyView.This review systematically summarizes recent advances in aggregation‐induced emission (AIE) materials for in vitro diagnostics (IVD). It highlights probe design strategies—categorizing them into direct‐responsive, indirect‐responsive, and nano‐immunoprobes—and their applications in detecting a wide range of biomarkers across diverse body fluids ...
Qi Liu +5 more
wiley +1 more source
Journal of Medical Case Reports, 2012 Introduction Fulminant cardiopulmonary failure is a severe complication of hand, foot and mouth diseases due to enterovirus 71 infection, with a high mortality rate. The treatment is mainly supportive with aggressive cardiopulmonary resuscitation.
Phan Phuc +6 more
doaj +1 more source
COPI is required for enterovirus 71 replication. [PDF]
PLoS ONE, 2012 Enterovirus 71 (EV71), a member of the Picornaviridae family, is found in Asian countries where it causes a wide range of human diseases. No effective therapy is available for the treatment of these infections.
Jianmin Wang, Zhiqiang Wu, Qi Jin
doaj +1 more source
Improving the inhibitors targeting enterovirus 71 3C proteinase [PDF]
, 2015 手足口病（HFMD）的频繁爆发，给许多婴幼儿带来痛苦甚至导致死亡。目前，没有任何疫苗和抗病毒治疗可用于预防和治疗手足口病。肠道病毒71型（EV71）是引起手足口病的主要病原体，它能够侵入中枢神经系统引起严重的后遗症。3C蛋白酶是EV71病毒复制过程中的一个重要蛋白酶，在EV71的成熟过程和拮抗宿主细胞的先天性免疫反应中有着重要作用。因此，EV713C蛋白酶是一个很好的抗EV71药物靶点。 AG7088最先是针对人病毒3C蛋白酶进行设计的，已被证实可有效抑制EV71病毒活性 ...
吴彩明
core
Routine Pediatric Enterovirus 71 Vaccination in China: a Cost-Effectiveness Analysis. [PDF]
, 2016 BACKGROUND: China accounted for 87% (9.8 million/11.3 million) of all hand, foot, and mouth disease (HFMD) cases reported to WHO during 2010-2014. Enterovirus 71 (EV71) is responsible for most of the severe HFMD cases.
Cowling, Benjamin J +14 more
core +3 more sources
Novel Wide‐Spectrum Virucidal Lipid Nanoparticles
Small, EarlyView.POSTAN is a novel broad‐spectrum antiviral nanoparticle that combines safety with potent virucidal activity. Composed of biocompatible lipids, it mimics heparan sulfate proteoglycans and lipid rafts exploited by viruses, thereby dismantling viral envelopes and blocking replication.
Yugo Araújo Martins +10 more
wiley +1 more source
First isolation of enterovirus 71 (EV-71) from Northern Brazil
Brazilian Journal of Infectious DiseasesEnterovirus 71 (EV-71) has been associated to cases of neurological disease in many countries including Brazil. This virus has now been reported from three of the five Brazilian regions.
Leticia Martins Lamarão +2 more
doaj +1 more source
Emerging Infectious Diseases, 2013 The epidemiology of enteroviral infection in South Korea during 1999–2011 chronicles nationwide outbreaks and changing detection and subtyping methods used over the 13-year period.
Ji-Yeon Hyeon +16 more
doaj +1 more source