Results 51 to 60 of about 43,168 (208)

Tinnitus and Coxsackie B infections: A case series [PDF]

open access: yes, 2007
Tinnitus is a frequent and often debilitating condition. There is consensus in the scientific community that there exist various forms of tinnitus, which differ in their pathogenesis.
Coors, Hermann   +6 more
core  

Routine Pediatric Enterovirus 71 Vaccination in China: a Cost-Effectiveness Analysis. [PDF]

open access: yes, 2016
BACKGROUND: China accounted for 87% (9.8 million/11.3 million) of all hand, foot, and mouth disease (HFMD) cases reported to WHO during 2010-2014. Enterovirus 71 (EV71) is responsible for most of the severe HFMD cases.
Cowling, Benjamin J   +14 more
core   +3 more sources

Hand, Foot and Mouth Disease Complicated with Central Nervous System Involvement in Taiwan in 1980–1981

open access: yesJournal of the Formosan Medical Association, 2007
Sixteen cases from the 1980-1981 Taiwan outbreak of hand, foot and mouth disease (HFMD) associated with central nervous system involvement were identified: nine had polio-like syndrome, four had encephalitis or encephalomyelitis, one had cerebellitis ...
Luan-Yin Chang   +6 more
doaj   +1 more source

Acute flaccid paralysis with anterior myelitis - California, June 2012-June 2014. [PDF]

open access: yes, 2014
In August 2012, the California Department of Public Health (CDPH) was contacted by a San Francisco Bay area clinician who requested poliovirus testing for an unvaccinated man aged 29 years with acute flaccid paralysis (AFP) associated with anterior ...
Ayscue, Patrick   +17 more
core   +1 more source

Enterovirus 71 uses cell surface heparan sulfate glycosaminoglycan as an attachment receptor [PDF]

open access: yes, 2013
Enterovirus 71 (EV-71) infections are usually associated with mild hand, foot, and mouth disease in young children but have been reported to cause severe neurological complications with high mortality rates.
Chan, Yoke Fun   +3 more
core   +1 more source

Harnessing Gut Microbiome–Brain–Liver Crosstalk: Novel Therapeutic Strategies for Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesMedicine Bulletin, EarlyView.
This review reveals the complex mechanisms by which the brain–gut–liver axis (particularly the gut microbiota and its metabolites) drives MASLD, highlighting the therapeutic value of using phages to target and eliminate pathogenic bacteria and their metabolic products.
Xingtao Zhao   +7 more
wiley   +1 more source

Improving the inhibitors targeting enterovirus 71 3C proteinase [PDF]

open access: yes, 2015
手足口病(HFMD)的频繁爆发,给许多婴幼儿带来痛苦甚至导致死亡。目前,没有任何疫苗和抗病毒治疗可用于预防和治疗手足口病。肠道病毒71型(EV71)是引起手足口病的主要病原体,它能够侵入中枢神经系统引起严重的后遗症。3C蛋白酶是EV71病毒复制过程中的一个重要蛋白酶,在EV71的成熟过程和拮抗宿主细胞的先天性免疫反应中有着重要作用。因此,EV713C蛋白酶是一个很好的抗EV71药物靶点。 AG7088最先是针对人病毒3C蛋白酶进行设计的,已被证实可有效抑制EV71病毒活性 ...
吴彩明
core  

Respiratory admissions and impact of COVID‐19 lockdowns for children with severe cerebral palsy

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
In a population cohort of children with severe cerebral palsy, there was a reduced frequency of hospitalization for respiratory illness during periods of restricted social contact, implemented to reduce transmission of COVID‐19. This mirrored trends in the wider population and underlines the importance of community viral transmission in these children.
Susan M. Reid   +9 more
wiley   +1 more source

Sentinel surveillance for human enterovirus 71 in Sarawak, Malaysia: lessons from the first 7 years

open access: yesBMC Public Health, 2006
Background A major outbreak of human enterovirus 71-associated hand, foot and mouth disease in Sarawak in 1997 marked the beginning of a series of outbreaks in the Asia Pacific region.
Yao Sik-King   +13 more
doaj   +1 more source

A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases [PDF]

open access: yes, 2017
Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize viral infection, which places the
Colombo, Maria Isabel   +1 more
core   +2 more sources

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