Results 61 to 70 of about 43,168 (208)

Gasdermins: multifunctional effectors of membrane permeabilization across cellular compartments

The FEBS Journal, EarlyView.
Gasdermins (GSDMs) are pore‐forming proteins best known for driving pyroptosis through plasma membrane (PM) permeabilization. Beyond triggering inflammatory cell death, GSDMs can also associate with organelle membranes, including mitochondria, lysosomes, ER, and nucleus, where they modulate membrane integrity and cellular signaling.
Eleonora Margheritis, Nadine Gehle, Katia Cosentino   +2 more
wiley   +1 more source

Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus. [PDF]

, 2017
The present study examines the susceptibility of mouse induced pluripotent stem cell-derived neural precursor cells (iPSC-NPCs) to infection with the neurotropic JHM strain of mouse hepatitis virus (JHMV).
Lane, Thomas E, Mangale, Vrushali, Marro, Brett S, Plaisted, Warren C, Walsh, Craig M   +4 more
core   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Anti-Enterovirus 71 Agents of Natural Products

Molecules, 2015
This review, with 42 references, presents the fascinating area of anti-enterovirus 71 natural products over the last three decades for the first time. It covers literature published from 2005–2015 and refers to compounds isolated from biogenic sources ...
Liyan Wang, Junfeng Wang, Lishu Wang, Shurong Ma, Yonghong Liu   +4 more
doaj   +1 more source

Epidemiology and Clinical Impact of Confirmed Respiratory Viral Infections in Solid Organ Transplant Recipients

Transplant Infectious Disease, EarlyView.
ABSTRACT Background Respiratory viral infections (RVIs) can have distinct clinical presentations and outcomes in non‐lung solid organ transplant (SOT) recipients compared to non‐transplant and lung transplant patients. Understanding their impact is crucial for improving patient care and outcomes.
Manon L. M. Prins, Ernst D. van Dokkum, Aiko P. J. de Vries, Maarten E. Tushuizen, Danny van der Helm, Edwin M. Spithoven, Irene M. van der Meer, Eduard M. Scholten, Albert M. Vollaard, Saskia le Cessie, Leo G. Visser, Geert H. Groeneveld   +11 more
wiley   +1 more source

Clinical and laboratory features of enteroviral meningitis course in adults and children

Zaporožskij Medicinskij Žurnal, 2017
Objective – to determine the frequency of serous meningitis of enteroviral etiology and find out their clinical and laboratory features. Materials and Methods. The study included 51 patients with serous meningitis.
D. A. Zadiraka, E. V. Riabokon, E. V. Usacheva, A. М. Kamyshny   +3 more
doaj   +1 more source

Enterovirus 71, One Virus and Many Stories

Pediatrics and Neonatology, 2008
Enterovirus 71 (EV71) has emerged as a significant cause of brainstem encephalitis and acute flaccid paralysis in Taiwan. It may be complicated by autonomic nervous system dysregulation and pulmonary edema (PE).
Shih-Min Wang, Tzong-Shiann Ho, Ching-Fen Shen, Ching-Chuan Liu   +3 more
doaj   +1 more source

Complete genome sequencing and analysis of six enterovirus 71 strains with different clinical phenotypes [PDF]

, 2013
BACKGROUND: Hand, foot and mouth diseases (HFMD) caused by enterovirus 71(EV71) presents a broad spectrum of clinical manifestations ranging from mild febrile disease to fatal neurolocal disease. However, the mechanism of virulence is unknown.
Cheng-xi Sun, Feng Gao, Fu-lu Chu, Hong-ling Wen, Lu-ying Si, Shu-bin Hao, Xiao-jing Yuan, Zhi-yu Wang   +7 more
core   +2 more sources

Diagnosis and management of reactive infectious mucocutaneous eruption

Journal of Hospital Medicine, Volume 20, Issue 11, Page 1212-1216, November 2025.
Abstract Medicine's clinical understanding of reactive infectious mucocutaneous eruption (RIME) has evolved over time. It was previously described as Mycoplasma pneumoniae‐induced rash and mucositis (MIRM), and before that as a variant of Stevens‐Johnson Syndrome/Toxic Epidermal Necrolysis. Here, we summarize the current understanding of best practices
Nicole Damari, Abbie Goodman, Catherine Bridges   +2 more
wiley   +1 more source

A new treatment for neurogenic inflammation caused by EV71 with CR2-targeted complement inhibitor [PDF]

, 2012
BACKGROUND: Enterovirus 71 (EV71), one of the most important neurotropic EVs, has caused death and long-term neurological sequelae in hundreds of thousands of young children in the Asia-Pacific region in the past decade.
Carl Atkinson, Chaojie Yang, Chuanfu Zhang, Fei Qiao, Guang Yang, Hongbin Song, Jian Wang, Jing Li, Leili Jia, Liuyu Huang, Lixue Song, Nan Liu, Shaofu Qiu, Stephen Tomlinson, Wenli Su, Yansong Sun, Yong Wang, Zhenjun Li, Zhongqiang Wang   +18 more
core   +1 more source