Results 61 to 70 of about 41,705 (223)

RNA interference against Enterovirus 71 infection

Virology, 2005
Enterovirus 71 (EV71) is a highly infectious major causative agent of hand, foot, and mouth disease (HFMD) which could lead to severe neurological complications. There is currently no effective therapy against EV71. In this study, RNA interference (RNAi) is employed as a therapeutic approach for specific viral inhibition.
Sim, Adrian Chong Nyi, Luhur, Arthur, Tan, Theresa May Chin, Cho, Vincent Tak Kwong, Poh, Chit Laa   +4 more
openaire   +3 more sources

Epigenetic analyses suggest different pathways during pregnancy for development of Type 1 diabetes in children with high versus low‐neutral human leukocyte antigen‐risk

Journal of Internal Medicine, EarlyView.
Abstract Background and objective The development of Type 1 diabetes (T1D) is shaped by genetic predisposition and epigenetic regulation. Human leukocyte antigen (HLA) risk alleles are major genetic determinants, but the epigenetic landscape in relation to disease onset remains unclear.
Shamila D. Alipoor, Angelica Ahrens, Julia Åkesson, Thomas Hillerton, Mika Gustafsson, Maria Lerm, Johnny Ludvigsson   +6 more
wiley   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Hand, Foot and Mouth Disease Complicated with Central Nervous System Involvement in Taiwan in 1980–1981

Journal of the Formosan Medical Association, 2007
Sixteen cases from the 1980-1981 Taiwan outbreak of hand, foot and mouth disease (HFMD) associated with central nervous system involvement were identified: nine had polio-like syndrome, four had encephalitis or encephalomyelitis, one had cerebellitis ...
Luan-Yin Chang, Chin-Yun Lee, Chuan-Liang Kao, Tsui-Yen Fang, Chun-Yi Lu, Ping-Ing Lee, Li-Min Huang   +6 more
doaj   +1 more source

Tinnitus and Coxsackie B infections: A case series [PDF]

, 2007
Tinnitus is a frequent and often debilitating condition. There is consensus in the scientific community that there exist various forms of tinnitus, which differ in their pathogenesis.
Coors, Hermann, Elgoyhen, Ana Belen, Kleinjung, Tobias, Landgrebe, Michael, Langguth, Berthold, Stadtlaender, Hans, Vielsmeier, Veronika   +6 more
core  

Routine Pediatric Enterovirus 71 Vaccination in China: a Cost-Effectiveness Analysis. [PDF]

, 2016
BACKGROUND: China accounted for 87% (9.8 million/11.3 million) of all hand, foot, and mouth disease (HFMD) cases reported to WHO during 2010-2014. Enterovirus 71 (EV71) is responsible for most of the severe HFMD cases.
Cowling, Benjamin J, Farrar, Jeremy J, Grenfell, Bryan T, Jit, Mark, Lau, Eric HY, Leung, Gabriel M, Leung, Kathy, Liao, Qiaohong, Takahashi, Saki, Wu, Joseph T, Xing, Weijia, Yang, Bingyi, Yang, Juan, Yu, Hongjie, Zheng, Yaming   +14 more
core   +3 more sources

Sophocarpine against enterovirus 71 in vitro

Experimental and Therapeutic Medicine, 2017
Sophocarpine (SCA) is a bioactive alkaloid present in Sophoraflavescens Ait. The present study demonstrated that SCA inhibited enterovirus 71 (EV71) infection in Vero cells. The results indicated that the 50% cytotoxicity concentration of SCA for Vero cells was 1,346 µg/ml, and the 50% inhibition concentration of SCA against EV71 was 350 µg/ml.
Zengjun, Jin, Lixin, Yang, Guotao, Ding, Guoxing, Yang, Yonghong, Han, Xia, Zhang, Weihao, Li   +6 more
openaire   +3 more sources

Clinical and laboratory features of enteroviral meningitis course in adults and children

Zaporožskij Medicinskij Žurnal, 2017
Objective – to determine the frequency of serous meningitis of enteroviral etiology and find out their clinical and laboratory features. Materials and Methods. The study included 51 patients with serous meningitis.
D. A. Zadiraka, E. V. Riabokon, E. V. Usacheva, A. М. Kamyshny   +3 more
doaj   +1 more source

Pan-viral serology implicates enteroviruses in acute flaccid myelitis. [PDF]

, 2019
Since 2012, the United States of America has experienced a biennial spike in pediatric acute flaccid myelitis (AFM)1-6. Epidemiologic evidence suggests non-polio enteroviruses (EVs) are a potential etiology, yet EV RNA is rarely detected in cerebrospinal
Banerji, Debarko, Benson, Leslie, Bove, Riley, Briggs, Benjamin, Cheung, Carly K, Chitnis, Tanuja, Chiu, Charles Y, Chu, Victoria, Crawford, Emily D, DeRisi, Joseph L, Ding, Joy Z, Dominguez, Samuel R, Gelfand, Amy A, Glaser, Carol A, Gorman, Mark P, Hauser, Stephen L, Hawes, Isobel A, Johnson-Kerner, Bethany L, Khan, Lillian M, Konopka-Anstadt, Jennifer L, Krishnamoorthy, Kalpathy S, Lopez, Adriana S, Lyden, Amy, Marine, Rachel L, McMillan, Hugh J, Messacar, Kevin, Nash, Kendall, Ng, Terry Fei Fan, Nix, W Allan, O'Donovan, Brian D, Oberste, M Steven, Pak, John E, Ramachandran, Prashanth S, Ramesh, Akshaya, Sample, Hannah A, Schubert, Ryan D, Sit, Rene, Soldatos, Ariane, Sowa, Gavin M, Tan, Michelle, Tato, Cristina M, Wadford, Debra A, Wilson, Michael R, Wu, Wesley, Yen, Cynthia, Zorn, Kelsey C   +45 more
core  

A Challenging Presentation of Mycoplasma pneumoniae: Mild Hepatic Dysfunction With Persistent Leukocytosis in a Pediatric Patient

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Mycoplasma pneumoniae (MP) is a common pediatric respiratory pathogen that can rarely present with extrapulmonary manifestations such as hepatic involvement. Recognition of hepatic dysfunction in this context is important for accurate diagnosis and timely therapy.
Robert J. Heins, Sierra Scott, Stephen Mock   +2 more
wiley   +1 more source