Results 61 to 70 of about 44,110 (248)

Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus. [PDF]

, 2017
The present study examines the susceptibility of mouse induced pluripotent stem cell-derived neural precursor cells (iPSC-NPCs) to infection with the neurotropic JHM strain of mouse hepatitis virus (JHMV).
Lane, Thomas E, Mangale, Vrushali, Marro, Brett S, Plaisted, Warren C, Walsh, Craig M   +4 more
core   +1 more source

Unraveling the Motions behind Enterovirus 71 Uncoating [PDF]

Biophysical Journal, 2018
Enterovirus 71 can be a severe pathogen in small children and immunocompromised adults. Virus uncoating is a critical step in the infection of the host cell; however, the mechanisms that control this process remain poorly understood. We applied normal mode analysis and perturbation response scanning to several complexes of the virus capsid and present ...
Ross, Caroline Jane, Atılgan, Ali Rana, Taştan Bishop, Özlem, Atılgan, Canan   +3 more
openaire   +4 more sources

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Pan-viral serology implicates enteroviruses in acute flaccid myelitis. [PDF]

, 2019
Since 2012, the United States of America has experienced a biennial spike in pediatric acute flaccid myelitis (AFM)1-6. Epidemiologic evidence suggests non-polio enteroviruses (EVs) are a potential etiology, yet EV RNA is rarely detected in cerebrospinal
Banerji, Debarko, Benson, Leslie, Bove, Riley, Briggs, Benjamin, Cheung, Carly K, Chitnis, Tanuja, Chiu, Charles Y, Chu, Victoria, Crawford, Emily D, DeRisi, Joseph L, Ding, Joy Z, Dominguez, Samuel R, Gelfand, Amy A, Glaser, Carol A, Gorman, Mark P, Hauser, Stephen L, Hawes, Isobel A, Johnson-Kerner, Bethany L, Khan, Lillian M, Konopka-Anstadt, Jennifer L, Krishnamoorthy, Kalpathy S, Lopez, Adriana S, Lyden, Amy, Marine, Rachel L, McMillan, Hugh J, Messacar, Kevin, Nash, Kendall, Ng, Terry Fei Fan, Nix, W Allan, O'Donovan, Brian D, Oberste, M Steven, Pak, John E, Ramachandran, Prashanth S, Ramesh, Akshaya, Sample, Hannah A, Schubert, Ryan D, Sit, Rene, Soldatos, Ariane, Sowa, Gavin M, Tan, Michelle, Tato, Cristina M, Wadford, Debra A, Wilson, Michael R, Wu, Wesley, Yen, Cynthia, Zorn, Kelsey C   +45 more
core  

RNA interference against Enterovirus 71 infection

Virology, 2005
Enterovirus 71 (EV71) is a highly infectious major causative agent of hand, foot, and mouth disease (HFMD) which could lead to severe neurological complications. There is currently no effective therapy against EV71. In this study, RNA interference (RNAi) is employed as a therapeutic approach for specific viral inhibition.
Sim, Adrian Chong Nyi, Luhur, Arthur, Tan, Theresa May Chin, Cho, Vincent Tak Kwong, Poh, Chit Laa   +4 more
openaire   +3 more sources

Epidemiology and Clinical Impact of Confirmed Respiratory Viral Infections in Solid Organ Transplant Recipients

Transplant Infectious Disease, EarlyView.
ABSTRACT Background Respiratory viral infections (RVIs) can have distinct clinical presentations and outcomes in non‐lung solid organ transplant (SOT) recipients compared to non‐transplant and lung transplant patients. Understanding their impact is crucial for improving patient care and outcomes.
Manon L. M. Prins, Ernst D. van Dokkum, Aiko P. J. de Vries, Maarten E. Tushuizen, Danny van der Helm, Edwin M. Spithoven, Irene M. van der Meer, Eduard M. Scholten, Albert M. Vollaard, Saskia le Cessie, Leo G. Visser, Geert H. Groeneveld   +11 more
wiley   +1 more source

Acute flaccid paralysis with anterior myelitis - California, June 2012-June 2014. [PDF]

, 2014
In August 2012, the California Department of Public Health (CDPH) was contacted by a San Francisco Bay area clinician who requested poliovirus testing for an unvaccinated man aged 29 years with acute flaccid paralysis (AFP) associated with anterior ...
Ayscue, Patrick, Centers for Disease Control and Prevention (CDC), Clayton, Anna, Feikin, Daniel, Glaser, Carol, Harriman, Kathleen, Nix, William Allan, Padilla, Tasha, Pan, Chao, Reichel, John, Sejvar, James, Sheriff, Heather, Van Haren, Keith, Waldron, Paul, Watt, James, Waubant, Emmanuelle, Yagi, Shigeo, Yen, Cynthia   +17 more
core   +1 more source

Enterovirus 71 uses cell surface heparan sulfate glycosaminoglycan as an attachment receptor [PDF]

, 2013
Enterovirus 71 (EV-71) infections are usually associated with mild hand, foot, and mouth disease in young children but have been reported to cause severe neurological complications with high mortality rates.
Chan, Yoke Fun, Poh, Chit Laa *, Sam, I-Ching, Tan, Chee Wah   +3 more
core   +1 more source

Stewardship of Molecular Diagnostics in Transplant Viral Infections

Transplant Infectious Disease, EarlyView.
ABSTRACT The transplant environment requires special considerations when testing for viral infections as immunosuppression results in atypical infection profiles. Microbes otherwise considered commensals or causing mild disease can lead to severe infections in transplant environments. Therefore, guidelines tend to recommend broader microbial testing in
Scott Sugden, David Reynoso, Reema Mathew, Michael Loeffelholz   +3 more
wiley   +1 more source

Hand, Foot and Mouth Disease Complicated with Central Nervous System Involvement in Taiwan in 1980–1981

Journal of the Formosan Medical Association, 2007
Sixteen cases from the 1980-1981 Taiwan outbreak of hand, foot and mouth disease (HFMD) associated with central nervous system involvement were identified: nine had polio-like syndrome, four had encephalitis or encephalomyelitis, one had cerebellitis ...
Luan-Yin Chang, Chin-Yun Lee, Chuan-Liang Kao, Tsui-Yen Fang, Chun-Yi Lu, Ping-Ing Lee, Li-Min Huang   +6 more
doaj   +1 more source