Results 51 to 60 of about 44,143 (229)

SARS‐CoV‐2 nucleocapsid protein variants have differential RNA chaperone activity

The FEBS Journal, EarlyView.
The SARS‐CoV‐2 nucleocapsid (N) protein facilitates RNA annealing through its RBD–IDR2–CTD region, identifying it as a functional RNA chaperone. The Omicron BA.5 variant shows reduced chaperone activity compared to the Wuhan wild‐type protein. Although phosphorylation has no effect on wild‐type N, phosphomimetic modification of BA.5 N restores its RNA ...
Sabrina Babl, Julia M. Seidel, Fabian Kugler, Elisabeth Silberhorn, Anna Ludwig, Jonas Abel, Sophia Winklbauer, Niklas Schaub, Silvia Materna‐Reichelt, Kamran Honarnejad, Nataša Stojanović Gužvić, Gernot Längst   +11 more
wiley   +1 more source

Enterovirus A71 vaccine effectiveness in preventing enterovirus A71 infection among medically-attended hand, foot, and mouth disease cases, Beijing, China

Human Vaccines & Immunotherapeutics, 2019
Introduction: Enterovirus A71(EV-A71)-associated hand, foot, and mouth disease (HFMD) has been reported worldwide, and poses a particularly heavy burden on patients, families, and society in China. Three Chinese companies have licensed inactivated EV-A71
Xiaoli Wang, Zhijie An, Da Huo, Lei Jia, Jie Li, Yang Yang, Zhichao Liang, Quanyi Wang, Huaqing Wang   +8 more
doaj   +1 more source

An epidemiological surveillance of hand foot and mouth disease in paediatric patients and in community: A Singapore retrospective cohort study, 2013-2018.

PLoS Neglected Tropical Diseases, 2021
BackgroundWhile hand, foot and mouth disease (HFMD) is primarily self-resolving-soaring incidence rate of symptomatic HFMD effectuates economic burden in the Asia-Pacific region.
Nyo Min, Yasmin Hui Binn Ong, Alvin X Han, Si Xian Ho, Emmerie Wong Phaik Yen, Kenneth Hon Kim Ban, Sebastian Maurer-Stroh, Chia Yin Chong, Justin Jang Hann Chu   +8 more
doaj   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Successful Treatment of Severe Purpura Fulminans With Anakinra

Pediatric Dermatology, EarlyView.
ABSTRACT Purpura fulminans (PF) is a rare, often fatal pediatric condition characterized by intravascular thrombosis and hemorrhagic infarction of the skin. A timely diagnosis and treatment are paramount to prevent the involvement of internal organs, causing disseminated intravascular coagulation and gangrene of the extremities.
Francesco Zulian, Luca Spiezia, Antonio Amabile, Francesca Tirelli, Alessandra Meneghel   +4 more
wiley   +1 more source

In Vivo Persistence of Human Rhinoviruses in Immunosuppressed Patients.

PLoS ONE, 2017
Several species of the genus Enterovirus cause persistent infections in humans. Human rhinovirus (HRV) infections are generally self-limiting but occasionally persistent infections have been described.
Ilka Engelmann, Anny Dewilde, Mouna Lazrek, Mathilde Batteux, Aminati Hamissi, Ibrahim Yakoub-Agha, Didier Hober   +6 more
doaj   +1 more source

Enterovirus and enterovirus infections.

Annals of the Academy of Medicine, Singapore, 1988
An account of the nature of enterovirus and enterovirus infections with special reference to experiences encountered in Singapore is presented. The most common of enterovirus epidemic diseases since 1970 is Acute Haemorrhagic Conjunctivitis caused by Coxsackievirus A24 variant and Enterovirus type 70. Enterovirus of various serotypes were isolated from
M, Yin-Murphy, M C, Phoon, B, Ishak
openaire   +1 more source

Antibody Serologies and Diagnostic Considerations in Reactive Infectious Mucocutaneous Eruption

Pediatric Dermatology, EarlyView.
ABSTRACT Reactive infectious mucocutaneous eruption (RIME) is an uncommon, post‐infectious mucocutaneous condition often associated with Mycoplasma pneumoniae, but which can be triggered by other pathogens. We retrospectively reviewed eight young adult patients diagnosed with RIME over a 10‐year period, all of whom had positive Mycoplasma pneumoniae ...
Aaron D. Smith, Olivia Cohen, Peter Jowdy, Catherine E. Lyons, Lauren Yi, Barrett Zlotoff   +5 more
wiley   +1 more source

Application of Syndromic Panels for respiratory Tract Infections in Lung Transplantation: A Critical Review on Current Evidence and Future Perspectives

Transplant Infectious Disease, EarlyView.
Limited data on syndromic panels for detecting respiratory tract infections in lung transplant candidates and recipients are available. While these panels provide a rapid turnaround time, they may fail to identify specific pathogens relevant in this setting, such as fungi.
Andrea Lombardi, Giulia Renisi, Arianna Liparoti, Chiara Bobbio, Alessandra Bandera   +4 more
wiley   +1 more source

Clinical manifestations of CNS infections caused by enterovirus type 71 [PDF]

Korean Journal of Pediatrics, 2011
PurposeEnterovirus 71, one of the enteroviruses that are responsible for both hand-foot-and-mouth disease and herpangina, can cause neural injury. During periods of endemic spread of hand-foot-andmouth disease caused by enterovirus 71, CNS infections are
Cheol Soon Choi, Yun Jung Choi, Ui Yoon Choi, Ji Whan Han, Dae Chul Jeong, Hyun Hee Kim, Jong Hyun Kim, Jin Han Kang   +7 more
doaj   +1 more source