Results 41 to 50 of about 17,800 (195)

A Case of Multiple Mitochondrial Dysfunctions Syndrome 1 and Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Multiple mitochondrial dysfunctions syndrome 1 (MMDS1, MIM #605711) due to NFU1 gene defects is an ultra‐rare autosomal recessive inborn error of metabolism associated with reduced function of NFU1 iron–sulfur cluster (ISC) scaffold protein.
Charles R. DiFalco, Aaron Williams, Claudia Soler‐Alfonso, Emily Waskow, Elizabeth Mizerik, Fernando Scaglia, Chaya N. Murali   +6 more
wiley   +1 more source

Aseptic Meningitis Epidemic during a West Nile Virus Avian Epizootic

Emerging Infectious Diseases, 2003
While enteroviruses have been the most commonly identified cause of aseptic meningitis in the United States, the role of the emerging, neurotropic West Nile virus (WNV) is not clear.
Kathleen G. Julian, James A. Mullins, Annette Olin, Heather Peters, W. Allan Nix, M. Steven Oberste, Judith C. Lovchik, Amy Bergmann, Ross J. Brechner, Robert A. Myers, Anthony A. Marfin, Grant L. Campbell   +11 more
doaj   +1 more source

Enteroviruses in the etiology of acute respiratory viral infections in children, Novosibirsk, Russia

Юг России: экология, развитие
Aim. To assess the contribution of human enteroviruses to the overall structure of acute respiratory viral infections in children in Novosibirsk during the epidemic season 2022–2023.   Material and Methods.
O. G. Kurskaya, T. A. Saroyan, A. R. Nokhova, N. A. Dubovitskiy, A. A. Derko, P. S. Basova, T. A. Gutova, M. V. Solomatina, T. A. Murashkina, K. A. Sharshov   +9 more
doaj   +1 more source

Enterovirus Replication Organelles and Inhibitors of Their Formation

Frontiers in Microbiology, 2020
Enteroviral replication reorganizes the cellular membrane. Upon infection, viral proteins and hijacked host factors generate unique structures called replication organelles (ROs) to replicate their viral genomes.
Xinhong Li, Xinhong Li, Xinhong Li, Mingshu Wang, Mingshu Wang, Mingshu Wang, Anchun Cheng, Anchun Cheng, Anchun Cheng, Xingjian Wen, Xingjian Wen, Xingjian Wen, Xumin Ou, Xumin Ou, Xumin Ou, Sai Mao, Sai Mao, Sai Mao, Qun Gao, Qun Gao, Qun Gao, Di Sun, Di Sun, Di Sun, Renyong Jia, Renyong Jia, Renyong Jia, Qiao Yang, Qiao Yang, Qiao Yang, Ying Wu, Ying Wu, Ying Wu, Dekang Zhu, Dekang Zhu, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Shun Chen, Shun Chen, Shun Chen, Mafeng Liu, Mafeng Liu, Mafeng Liu, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Yunya Liu, Yunya Liu, Yunya Liu, Yanling Yu, Yanling Yu, Yanling Yu, Ling Zhang, Ling Zhang, Ling Zhang, Bin Tian, Bin Tian, Leichang Pan, Leichang Pan, Xiaoyue Chen, Xiaoyue Chen, Xiaoyue Chen   +62 more
doaj   +1 more source

Nail Disorders in Systemic Conditions

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail findings in children can be indicative of an underlying systemic disease. Many of these findings are seen in multiple entities and are not specific to one disease. The importance of specifically examining for these nail changes cannot be overstated.
Jane Sanders Bellet
wiley   +1 more source

Detection of Nonpolio Enteroviruses among children with acute flaccid paralysis from institutions and from migrants’ families

Журнал инфектологии, 2014
Aim: to study of the frequency of isolation and determination of the spectrum of enterovirus serotypes excreted by children living in the North-Western region of Russia and children arriving in this region from unsafe territories.Materials and methods ...
N. I. Romanenkova, O. I. Kanaeva, M. A. Bichurina, N. R. Rozaeva   +3 more
doaj   +1 more source

Neurodevelopmental Disorder with Dystonia and Chorea Linked to De Novo Variants in the Splicing Regulator SRRM4

Movement Disorders, EarlyView.
Abstract Background SRRM4 is an exclusively neural‐expressed splicing‐factor gene not yet associated with a monogenic condition. Objective We sought to delineate movement disorders caused by SRRM4 variants. De novo splice‐donor‐site variants at position +2 of intron 5 of SRRM4 (c.464+2T>C, c.464+2T>A) occurred in three unrelated patients with dystonia ...
Philip Harrer, Volker Kittke, Alice Saparov, Alexej Knaus, Shimriet Zeidler, Rachel Schot, Florian Kraft, Matthias Begemann, Suzanna Koudijs, Ugo Sorrentino, Chen Zhao, Ivana Dzinovic, Martin Pavlov, Elisabeth Graf, Antonia M. Stehr, Peter M. Krawitz, Christian Wilhelm, Saskia Biskup, Fahd Alsalloum, Steffen Berweck, Juliane Winkelmann, Konrad Oexle, Ingo Kurth, G. Christoph Korenke, Michael Zech   +24 more
wiley   +1 more source

Role of Enterovirus ECHO 30 as the etiological agent of enterovirus infection in the North-West of Russia in 2013

Журнал инфектологии, 2014
In 2013 after two previous years when the situation had been calm the incidence rates of enterovirus infection significantly increased on certain territories of the North-West of Russia. In Novgorod and Vologda regions and in Saint-Petersburg enterovirus
M. A. Bichurina, N. I. Romanenkova, L. N. Golitsyna, N. R. Rozaeva, O. I. Kanaeva, S. G. Fomina, T. I. Krainova, L. A. Shishko, T. A. Gordienko, V. A. Pianykh, T. G. Ivanova, S. N. Smelkov, M. V. Lesnikova, N. A. Novikova   +13 more
doaj   +1 more source

Association of Salivary Micro Ribonucleic Acid Levels With the Severity of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Children

Pediatric Discovery, EarlyView.
This cohort study of 395 children (mean age 7 years) with SARS‐CoV‐2 demonstrates that measuring levels of miR‐296‐5p in saliva at the time of initial clinical presentation may aid the prognosis of severe symptoms. ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) may impact immune‐related micro ribonucleic acids (miRNAs).
Steven D. Hicks, Dongxiao Zhu, Nirupama Kannikeswaran, Kathleen Meert, Wei Chen, Rhea Sullivan, Srinivasan Suresh, Usha Sethuraman   +7 more
wiley   +1 more source

Oncolytic Vaccinia Virus‐HSP70‐shRNA Amplifies Viral Replication, ROS/Autophagy, and Immunity to Fight Colorectal Cancer

Cancer Science, EarlyView.
OncoVV‑shHSP70, a vaccinia virus silencing HSP70, demonstrated potent antitumor efficacy in colorectal cancer cell lines, as well as in syngeneic, xenograft, and humanized mouse models. In cell lines, oncoVV‑shHSP70 promoted viral oncolysis and cytokine production through a self‑reinforcing cycle of ROS‑autophagy. In both CT26 and SW620‑humanized mouse
Rentao Yuan, Ruikang Liu, Fangying Shao, Zheqi Cai, Yingfei Fang, Kan Chen, Yanrong Zhou, Ting Ye, Gongchu Li   +8 more
wiley   +1 more source