Results 51 to 60 of about 30,893 (233)

Viruses associated with pneumonia in adults. [PDF]

, 2012
Viral pneumonia, which is typically associated with disease in childhood, is increasingly recognized as causing problems in adults. Certain viruses, such as influenza virus, can attack fully immunocompetent adults, but many viruses take advantage of more-
Cesario, Thomas C
core   +1 more source

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

Advanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun, Yong Li, Bagen Temur, Yuanqing Lin, Yuhang Liu, Le Yi, Zheng Sun, Gang Zhang, Jun Li, Yu Guo, Linchuan Li, Jinshan Cai, Wenliang Tian, Gen Meng, Lingling Jiang, Min Fang, Fuying Ding, Xuezhang Zhou, Changchun Tu, Biao He   +19 more
wiley   +1 more source

Enterovirus Replication Organelles and Inhibitors of Their Formation

Frontiers in Microbiology, 2020
Enteroviral replication reorganizes the cellular membrane. Upon infection, viral proteins and hijacked host factors generate unique structures called replication organelles (ROs) to replicate their viral genomes.
Xinhong Li, Xinhong Li, Xinhong Li, Mingshu Wang, Mingshu Wang, Mingshu Wang, Anchun Cheng, Anchun Cheng, Anchun Cheng, Xingjian Wen, Xingjian Wen, Xingjian Wen, Xumin Ou, Xumin Ou, Xumin Ou, Sai Mao, Sai Mao, Sai Mao, Qun Gao, Qun Gao, Qun Gao, Di Sun, Di Sun, Di Sun, Renyong Jia, Renyong Jia, Renyong Jia, Qiao Yang, Qiao Yang, Qiao Yang, Ying Wu, Ying Wu, Ying Wu, Dekang Zhu, Dekang Zhu, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Shun Chen, Shun Chen, Shun Chen, Mafeng Liu, Mafeng Liu, Mafeng Liu, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Yunya Liu, Yunya Liu, Yunya Liu, Yanling Yu, Yanling Yu, Yanling Yu, Ling Zhang, Ling Zhang, Ling Zhang, Bin Tian, Bin Tian, Leichang Pan, Leichang Pan, Xiaoyue Chen, Xiaoyue Chen, Xiaoyue Chen   +62 more
doaj   +1 more source

Mass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field

Advanced Science, EarlyView.
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park, Zahra Rezaei, Nam Ho Bae, Donggee Rho, Da‐Seul Kim, EunYoung Go, YoungTae Seo, Seok Jae Lee, Won Chan Seo, Luke P. Lee, HeaYeon Lee, Su Ryon Shin   +11 more
wiley   +1 more source

Pan-viral serology implicates enteroviruses in acute flaccid myelitis. [PDF]

, 2019
Since 2012, the United States of America has experienced a biennial spike in pediatric acute flaccid myelitis (AFM)1-6. Epidemiologic evidence suggests non-polio enteroviruses (EVs) are a potential etiology, yet EV RNA is rarely detected in cerebrospinal
Banerji, Debarko, Benson, Leslie, Bove, Riley, Briggs, Benjamin, Cheung, Carly K, Chitnis, Tanuja, Chiu, Charles Y, Chu, Victoria, Crawford, Emily D, DeRisi, Joseph L, Ding, Joy Z, Dominguez, Samuel R, Gelfand, Amy A, Glaser, Carol A, Gorman, Mark P, Hauser, Stephen L, Hawes, Isobel A, Johnson-Kerner, Bethany L, Khan, Lillian M, Konopka-Anstadt, Jennifer L, Krishnamoorthy, Kalpathy S, Lopez, Adriana S, Lyden, Amy, Marine, Rachel L, McMillan, Hugh J, Messacar, Kevin, Nash, Kendall, Ng, Terry Fei Fan, Nix, W Allan, O'Donovan, Brian D, Oberste, M Steven, Pak, John E, Ramachandran, Prashanth S, Ramesh, Akshaya, Sample, Hannah A, Schubert, Ryan D, Sit, Rene, Soldatos, Ariane, Sowa, Gavin M, Tan, Michelle, Tato, Cristina M, Wadford, Debra A, Wilson, Michael R, Wu, Wesley, Yen, Cynthia, Zorn, Kelsey C   +45 more
core  

Large-Scale Survey of Human Enteroviruses in Wastewater Treatment Plants of a Metropolitan Area of Southern Italy [PDF]

, 2018
Human enteroviruses (HEVs) occur in high concentrations in wastewater and can contaminate receiving environmental waters, constituting a major cause of acute waterborne disease worldwide. In this study, we investigated the relative abundance, occurrence,
Amato, Concetta, Aurino, Sara, Battistone, Andrea, Buttinelli, Gabriele, Delogu, Roberto, Fiore, Stefano, Montuori, Paolo, Nardone, Antonio, Pennino, Francesca, Torre, Ida, Triassi, Maria   +10 more
core   +1 more source

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

Advanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang, Xiong Xie, Huidi Fan, Botao Wu, An Wang, Wenhao Dai, Zezhong Liu, Jian Li, Huoyan Tong, Jianan Li, Yujie Ren, Jinlin Wang, Xi Zhou, Hong Liu   +13 more
wiley   +1 more source

Aseptic Meningitis Epidemic during a West Nile Virus Avian Epizootic

Emerging Infectious Diseases, 2003
While enteroviruses have been the most commonly identified cause of aseptic meningitis in the United States, the role of the emerging, neurotropic West Nile virus (WNV) is not clear.
Kathleen G. Julian, James A. Mullins, Annette Olin, Heather Peters, W. Allan Nix, M. Steven Oberste, Judith C. Lovchik, Amy Bergmann, Ross J. Brechner, Robert A. Myers, Anthony A. Marfin, Grant L. Campbell   +11 more
doaj   +1 more source

Atypical Clinical Course of Griscelli Syndrome Type 2 With Primarily Neurologic Presentation and Adult‐Onset in a 46‐Year‐Old Male

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Griscelli Syndrome Type 2 (GS2) is a rare autosomal recessive disorder caused by pathogenic mutations in the RAB27A gene. Typically, it is characterized by cutaneous hypopigmentation, immunodeficiency, with or without neurological abnormalities secondary to hemophagocytic lymphohistiocytosis (HLH). Without treatment, GS2 often results in fatal
Dzhoy Papingi, Michael Kutsche, Helena Lichtenfeld, Fanny Kortüm, Angela Abicht, Laura Herrmann, Theresia Herget   +6 more
wiley   +1 more source

Monitoring the VDPV2 outbreak in Egypt during 2020–2021 highlights the crucial role of environmental surveillance and boosting immunization in combating Poliovirus

BMC Infectious Diseases
Background Poliovirus is a highly infectious enterovirus (EV) that primarily affects children and can lead to lifelong paralysis or even death. Vaccine-derived polioviruses (VDPVs) are a great threat since they are derived from the attenuated virus in ...
Menna R. Shabana, Amira Y. Zaghloul, Tamer H. El Shaarawy, Nooran S. Elleboudy, Khaled M. Aboshanab   +4 more
doaj   +1 more source