Results 71 to 80 of about 27,128 (236)

Novel pleconaril derivatives: influence of substituents in the isoxazole and phenyl rings on the antiviral activity against enteroviruses

European journal of medicinal chemistry, 2019
Today, there are no medicines to treat enterovirus and rhinovirus infections. In the present study, a series of novel pleconaril derivatives with substitutions in the isoxazole and phenyl rings was synthesized and evaluated for their antiviral activity ...
A. Egorova, Elena Kazakova, B. Jahn, S. Ekins, V. Makarov, M. Schmidtke   +5 more
semanticscholar   +1 more source

Harnessing Aggregation‐Induced Emission for Advanced Disease Diagnosis: Mechanisms, Strategies and Future Perspectives

Medicine Bulletin, EarlyView.
The figure was created in BioRender.com. ABSTRACT Accurate and early diagnosis remains a key challenge in modern disease management. Conventional diagnostic methods often suffer from limitations in sensitivity, spatial resolution, and practical usability.
Zizhuo Du, Li Song, Xingrui Chen, Jun Jing, Yingchen Wang, Yue Jiang, Jiahui Gao, Dan Li, Feiran Xie, Peihong Xiao, Ben Zhong Tang   +10 more
wiley   +1 more source

Role of Enterovirus ECHO 30 as the etiological agent of enterovirus infection in the North-West of Russia in 2013

Журнал инфектологии, 2014
In 2013 after two previous years when the situation had been calm the incidence rates of enterovirus infection significantly increased on certain territories of the North-West of Russia. In Novgorod and Vologda regions and in Saint-Petersburg enterovirus
M. A. Bichurina, N. I. Romanenkova, L. N. Golitsyna, N. R. Rozaeva, O. I. Kanaeva, S. G. Fomina, T. I. Krainova, L. A. Shishko, T. A. Gordienko, V. A. Pianykh, T. G. Ivanova, S. N. Smelkov, M. V. Lesnikova, N. A. Novikova   +13 more
doaj   +1 more source

Beyond the Kidney and Lung: Cutaneous and Mucosal Clues to Human Hantavirus Disease

International Journal of Dermatology, EarlyView.
Rodent exposure and aerosolized excreta can lead to hantavirus infection with systemic endothelial injury and capillary leak, resulting in thrombocytopenia and syndromes such as HPS/HCPS and HFRS/NE. Early dermatologic and mucosal findings, including flushing, conjunctival injection, petechiae/purpura, and mucosal bleeding, may provide important clues ...
Giuseppe Gallo, Pietro Quaglino, Simone Ribero   +2 more
wiley   +1 more source

MODERN POSSIBILITIES OF VIROLOGICAL DIAGNOSTICS OF POLIOMYELITIS

Журнал инфектологии, 2018
The review presents the data from the literature of our and foreign countries devoted to modern virologic diagnostics of poliomyelitis viruses of 1, 2, and 3 types that is especially topical in connection with WHO program on complete poliomyelitis ...
E. A. Murina, O. V. Goleva, Z. A. Osipova, A. L. Mukomolova   +3 more
doaj   +1 more source

When to consider an inborn error of immunity: clues for physicians

Internal Medicine Journal, EarlyView.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

Non-Polio Enteroviruses in Acute Flaccid Paralysis: Analysis of Surveillance in Iraq from 2018 to 2024

مجلة كلية الطب
Background: Acute flaccid paralysis surveillance, forms the basis for poliovirus eradication efforts and  provides useful data on non-polio enteroviruses, which are significant causes of acute flaccid paralysis in polio-free countries.
Nadia A. Nasir, Murad Th. Mehmoud, Muhi K. Al-Janabi, Khailil I. Mohammed   +3 more
doaj   +1 more source

Efficacy of inactivation of human enteroviruses by dual-wavelength germicidal ultraviolet (UV-C) light emitting diodes (LEDs).

Water, 2019
The efficacy of germicidal ultraviolet (UV-C) light emitting diodes (LEDs) was evaluated for inactivating human enteroviruses included on the United States Environmental Protection Agency (EPA)'s Contaminant Candidate List (CCL).
Hyoungmin Woo, Sara E. Beck, L. Boczek, K. M. Carlson, Nichole E. Brinkman, K. Linden, O. Lawal, S. Hayes, H. Ryu   +8 more
semanticscholar   +1 more source

Genetic basis of Asian diabetes

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Recent genomic studies in Asian populations have advanced our understanding of the diagnosis, pathophysiology, risk prediction, and precision care of diabetes. Monogenic diabetes, including maturity‐onset diabetes of the young (MODY) and mitochondrial diabetes, highlights the importance of genetic diagnosis for subtype‐specific care.
Takafumi Ojima, Toshimasa Yamauchi
wiley   +1 more source

Genomic analysis of high pathogenicity avian influenza viruses from Antarctica reveals multiple introductions from South America

Nature Communications
The spread of high pathogenic avian influenza virus (HPAIV) H5N1 clade 2.3.4.4b into Antarctica poses a major threat to polar wildlife. We report the detection of H5N1 in carcasses of eight species during the 2023-2024 and 2024-2025 austral summers in ...
Maria Ogrzewalska, Ralph Eric Thijl Vanstreels, Elisa Cavalcante Pereira, Emandi Campinas, Leonardo Correa Junior, Jennifer Oliveira Melo, Larissa Macedo, Luciana Reis Appolinario, Ighor Arantes, Martha Lima Brandao, Bruno Rocha Pribul, Claudio Marcos Rocha, Fabricio Souza Campos, Ueric José Borges de Souza, Bruna Paredes Galarza, Alanis Silva Melgarejo, Luciana Trilles, Lucas Machado Moreira, Wim Degrave, Maithê Magalhães, Daniel Moreira, Roberto do Val Vilela, Fernando Couto Motta, Marilda M. Siqueira, Paola Cristina Resende   +24 more
doaj   +1 more source