Results 141 to 150 of about 40,545 (235)

The Spatial Divergence of Hypometabolism and Atrophy in Mesial Temporal Lobe Epilepsy: Combining 18F‐FDG PET and Structural MRI for Predicting Postoperative Seizure Freedom

Human Brain Mapping, Volume 47, Issue 11, 01 August 2026.
Structural MRI and 18F‐FDG‐PET reveal distinct structure‐metabolism decoupling in temporal lobe epilepsy. A presurgical machine learning model integrating these complementary radiomics with clinical features robustly predicts postoperative seizure freedom, achieving prognostic efficacy that could rival models reliant on actual resection data.
Yuming Li, Fanglan Li, Danyang Cao, Qiuxing Lin, Peiwen Liu, Wei Li, Yingying Zhang, Xiang Huang, Kailing Huang, Wenhao Li, Xiuli Li, Rang Li, Xiutian Sima, Qiyong Gong, Dong Zhou, Dongmei An   +15 more
wiley   +1 more source

APOE4 and doxorubicin impair inhibitory interneuron function and homeostatic regulation in the entorhinal cortex. [PDF]

PLoS One
Luo N, Pandit H, Kalra S, Tran E, Mandelblatt J, Vicini S, Rebeck GW.   +6 more
europepmc   +1 more source

Astrocytes in Genetic Epilepsies: Supporting Actor or Key Player?

Journal of Neuroscience Research, Volume 104, Issue 8, August 2026.
Astrocytes contribute to the pathophysiology of acquired epilepsy. However, less is known about their contribution to genetic epilepsy syndromes which often exhibit frequent comorbidity with neurodevelopmental and psychiatric disorders. Epileptic seizures are also frequently present in neurodevelopmental disorders.
Jenny Lange, Erica Zhao, Ellie O'Connell, Olivia Gillham, Amy McTague   +4 more
wiley   +1 more source

Association of hippocampus, entorhinal cortex, and amygdala with thyroid function: a bilateral volumetric analysis. [PDF]

Thyroid Res
Hallab A, Alzheimer’s Disease Neuroimaging Initiative (ADNI).   +1 more
europepmc   +1 more source

Obstructive Sleep Apnea: Epidemiology, Pathophysiology, Complications, Diagnosis, Management, and Emerging Fibrosis‐Linked Remodeling

MedComm, Volume 7, Issue 8, August 2026.
Obstructive sleep apnea (OSA) is characterized by recurrent upper‐airway collapse, which generates key nocturnal stressors including intermittent hypoxia, sleep fragmentation, intrathoracic pressure stress, and sympathetic activation. These physiological disturbances converge on shared biological mechanisms, including oxidative stress, inflammation ...
Nhi Ho Thi Thuy, Thị Hằng Giang Phan, Ali Hussein Eid, Paola Maccioccu, Stefania Camboni, Gavino Casu, Anna Maria Posadino, Roberta Giordo, Gianfranco Pintus   +8 more
wiley   +1 more source

Biomarker‐Based Diagnosis and Care Pathways for Alzheimer's Disease in the Era of Disease‐Modifying Treatments: A Consensus Statement by Belgian Experts

European Journal of Neurology, Volume 33, Issue 8, August 2026.
ABSTRACT Background The recent approval of disease‐modifying therapies (DMTs) for early Alzheimer's disease (AD) marks a major shift in clinical practice. Biomarker confirmation of amyloid pathology is now required alongside clinical assessment, and blood‐based tests are improving accessibility.
Tim Van Langenhove, Sara Van Mossevelde, Marijke Miatton, Jan De Lepeleire, Rose Bruffaerts, Jean Christophe Bier, Kurt Segers, Jurn Verschraegen, Mirko Petrovic, Manfredi Ventura, Haroun Jedidi, Ingo Beyer, Eric Mormont, Rik Vandenberghe, Aline Delva, Christian Gilles, Donatienne Van Weehaeghe, Gaëtane Picard, Peter De Deyn, Mélanie Strauss, Evert Thiery, Eric Salmon, Gert Cypers, Joris Vlaemynck, Katrin Gillis, Jan Versijpt, Maria Bjerke, Anne Sieben, Bernard Hanseeuw, Sebastiaan Engelborghs, Olivier Deryck, on behalf of the BeDeCo members   +31 more
wiley   +1 more source

Sleep deprivation following hippocampus-dependent learning downscales synaptic inputs to lateral and medial entorhinal cortex interneurons. [PDF]

Sleep
Balendran V, Liu J, Wu K, Dong A, Aton SJ.   +4 more
europepmc   +1 more source

Dissecting the Strain and Sex Specific Connectome Signatures of Unanesthetized C57BL/6J and DBA/2J Mice Using Magnetic Resonance Imaging

Genes, Brain and Behavior, Volume 25, Issue 4, August 2026.
C57BL/6J and DBA/2J mice were used to investigate strain and sex‐specific features of the brain connectome in awake animals using magnetic resonance imaging (MRI). By combining resting‐state and diffusion MRI, we found significant differences in the motor, sensory, limbic, and salience networks between C57BL/6J and DBA/2J mice.
Tanzil M. Arefin, Hayreddin Said Ünsal, Thomas Neuberger, Nanyin Zhang, Helen M. Kamens   +4 more
wiley   +1 more source

Stepwise connectivity of the entorhinal cortex along connectomic gradients in Alzheimer's disease. [PDF]

Brain Commun
Tan JXM, Kang MS, Yeh YH, Bezgin G, Lussier FZ, Hong SJ, Isen J, Rahmouni N, Vitali P, Montembeault M, Klostranec JM, Macedo AC, Chan T, McLaurin J, Swardfager W, Bernhardt BC, Stefanovic B, Soucy JP, Gauthier S, Black SE, Rosa-Neto P, Ottoy J, Goubran M.   +22 more
europepmc   +1 more source

Gait Impairment and Alzheimer's Disease Pathology: A Narrative Review on Mechanistic Links

Geriatrics &Gerontology International, Volume 26, Issue 8, August 2026.
Gait impairment and AD‐related pathology may be linked through shared risks, preclinical AD changes, feedback effects of persistent gait dysfunction, and life‐course susceptibility, underscoring the importance of maintaining brain–body health across the lifespan. ABSTRACT In older adults, gait has emerged as an important indicator of overall health and
Ryota Sakurai, Manuel Montero‐Odasso
wiley   +1 more source