Insights Into the Biological Mechanisms and Multifunctional Health Benefits of Morelloflavone
Morelloflavone (MF), a biflavonoid from Garcinia and related species, exhibits broad human health benefits through antioxidant, anti‐inflammatory, anticancer, and metabolic regulatory effects. This review highlights its molecular mechanisms, biosynthesis, and emerging roles in chronic disease prevention, emphasizing systems biology and machine learning
Yi Liu +4 more
wiley +1 more source
Vulnerability of the locus coeruleus-entorhinal cortex white matter tract in autosomal dominant Alzheimer's disease. [PDF]
Koops EA +11 more
europepmc +1 more source
Active Vaccination Strategies for Alzheimer's Disease: An Expanded Review
Overview of immunotherapeutic strategies targeting Alzheimer's disease (AD) pathology and their clinical implications. (Left) Key neuropathological hallmarks of AD, including extracellular amyloid‐beta (Aβ) aggregates and intraneuronal hyperphosphorylated Tau (phospho‐Tau), converge to produce synaptic failure, neuroinflammation and neuronal ...
Antonella Comitato +2 more
wiley +1 more source
Directional dynamics in the entorhinal cortex of male mice driven by behavioral constraints. [PDF]
Liu R +8 more
europepmc +1 more source
Using [18F]‐SMBT‐1 PET, we longitudinally tracked MAO‐B–expressing reactive astrocytes during orofacial neuropathic pain development in rats, revealing region‐ and time‐specific astrocyte activation during pain chronification. ABSTRACT Chronic neuropathic pain represents a significant global health burden and is hypothesized to be maintained by an ...
Lewis S. Crawford +14 more
wiley +1 more source
Entorhinal cortex atrophy mediates the association of plasma p-tau181, GFAP, and NfL with cognitive impairment in Parkinson's disease. [PDF]
Wan Q +7 more
europepmc +1 more source
Global and Voxel‐Wise Brain Age Prediction Analyses Following Perinatal Stroke
ABSTRACT Perinatal stroke affects millions of individuals worldwide, often leading to lifelong complications for those who survive and who require targeted rehabilitation to limit disability. Although biological brain age prediction may be a valuable biomarker to analyze neurodevelopment following perinatal stroke and guide rehabilitation, there have ...
Ravi Amir Santiago Bullock +5 more
wiley +1 more source
Flexible neural representations of abstract structural knowledge in the human entorhinal cortex. [PDF]
Mark S +5 more
europepmc +1 more source
External Source Monitoring and Reality Monitoring: Meta‐Analysis of fMRI Studies
We conducted an fMRI meta‐analysis showing the overlapping and unique clusters involved in external source monitoring and reality monitoring. Our results show the peculiarities of each monitoring task better defining each process. ABSTRACT Being able to remember the origin of a particular memory is for times even more important than the memory itself ...
Beatriz Martín‐Luengo +2 more
wiley +1 more source
Entorhinal cortex represents task-relevant remote locations independently of CA1. [PDF]
Aery Jones EA +3 more
europepmc +1 more source

