Results 11 to 20 of about 40,545 (235)
Cortisol treatment impairs path integration and alters grid-like representations in the male human entorhinal cortex. [PDF]
PLoS BiologyAcute stress triggers the release of cortisol, which broadly affects cognitive processes. Path integration, a specific navigational process, relies heavily on grid cells in the entorhinal cortex.
Osman Akan +6 more
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Entorhinal cortex layer III Adgrl2 expression controls topographical circuit connectivity required for sequence learning [PDF]
Translational PsychiatryThe entorhinal cortex and hippocampus are interconnected brain regions required for episodic learning and memory. For this functional encoding, correct assembly of specific synaptic connections across this circuit is critical during development. To guide
Jordan D. Donohue +8 more
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Traces of Experience in the Lateral Entorhinal Cortex [PDF]
Current Biology, 2013 A growing body of evidence suggests that memories are stored in the hippocampus by integrating spatial information from specialized cell types in the medial entorhinal cortex (MEC) with nonspatial information from cells in the lateral entorhinal cortex (LEC).
Tsao, Albert +2 more
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康复学报, 2023 ObjectiveTo observe the correlation between the changes of entorhinal cortex-hippocampus nerve fibers and learning and memory function in the P301L-Tau mouse model of Alzheimer's disease (AD) and related molecular mechanism, so as to provide the evidence
CHEN Xiaocheng +4 more
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Nature Communications, 2022 Extensive studies concluded that homophilic interactions between pre- and postsynaptic teneurins, evolutionarily conserved cell-adhesion molecules, encode the specificity of synaptic connections.
Xuchen Zhang +3 more
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An Optimized Deep Learning Model for Predicting Mild Cognitive Impairment Using Structural MRI
Sensors, 2023 Early diagnosis of mild cognitive impairment (MCI) with magnetic resonance imaging (MRI) has been shown to positively affect patients’ lives. To save time and costs associated with clinical investigation, deep learning approaches have been used widely to
Esraa H. Alyoubi +3 more
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What Does the Anatomical Organization of the Entorhinal Cortex Tell Us?
Neural Plasticity, 2008 The entorhinal cortex is commonly perceived as a major input and output structure of the hippocampal formation, entertaining the role of the nodal point of cortico-hippocampal circuits. Superficial layers receive convergent cortical information, which is
Cathrin B. Canto +2 more
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Mapping sequence structure in the human lateral entorhinal cortex
eLife, 2019 Remembering event sequences is central to episodic memory and presumably supported by the hippocampal-entorhinal region. We previously demonstrated that the hippocampus maps spatial and temporal distances between events encountered along a route through ...
Jacob LS Bellmund +2 more
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Prenatal development of the human entorhinal cortex
Journal of Comparative Neurology, 2022 AbstractLittle is known about the development of the human entorhinal cortex (EC), a major hub in a widespread network for learning and memory, spatial navigation, high‐order processing of object information, multimodal integration, attention and awareness, emotion, motivation, and perception of time.
Goran Šimić +16 more
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Neural Plasticity, 2010 All neurons are not created equal. Certain cell populations in specific brain regions are more susceptible to age-related changes that initiate regional and system-level dysfunction.
Alexis M. Stranahan, Mark P. Mattson
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