Results 21 to 30 of about 41,716 (223)

Teneurins assemble into presynaptic nanoclusters that promote synapse formation via postsynaptic non-teneurin ligands

open access: yesNature Communications, 2022
Extensive studies concluded that homophilic interactions between pre- and postsynaptic teneurins, evolutionarily conserved cell-adhesion molecules, encode the specificity of synaptic connections.
Xuchen Zhang   +3 more
doaj   +1 more source

An Optimized Deep Learning Model for Predicting Mild Cognitive Impairment Using Structural MRI

open access: yesSensors, 2023
Early diagnosis of mild cognitive impairment (MCI) with magnetic resonance imaging (MRI) has been shown to positively affect patients’ lives. To save time and costs associated with clinical investigation, deep learning approaches have been used widely to
Esraa H. Alyoubi   +3 more
doaj   +1 more source

What Does the Anatomical Organization of the Entorhinal Cortex Tell Us?

open access: yesNeural Plasticity, 2008
The entorhinal cortex is commonly perceived as a major input and output structure of the hippocampal formation, entertaining the role of the nodal point of cortico-hippocampal circuits. Superficial layers receive convergent cortical information, which is
Cathrin B. Canto   +2 more
doaj   +1 more source

Mapping sequence structure in the human lateral entorhinal cortex

open access: yeseLife, 2019
Remembering event sequences is central to episodic memory and presumably supported by the hippocampal-entorhinal region. We previously demonstrated that the hippocampus maps spatial and temporal distances between events encountered along a route through ...
Jacob LS Bellmund   +2 more
doaj   +1 more source

Cortisol treatment impairs path integration and alters grid-like representations in the male human entorhinal cortex. [PDF]

open access: yesPLoS Biol
Acute stress triggers the release of cortisol, which broadly affects cognitive processes. Path integration, a specific navigational process, relies heavily on grid cells in the entorhinal cortex.
Akan O   +6 more
europepmc   +2 more sources

Selective Vulnerability of Neurons in Layer II of the Entorhinal Cortex during Aging and Alzheimer's Disease

open access: yesNeural Plasticity, 2010
All neurons are not created equal. Certain cell populations in specific brain regions are more susceptible to age-related changes that initiate regional and system-level dysfunction.
Alexis M. Stranahan, Mark P. Mattson
doaj   +1 more source

Neuronal Plasticity in the Entorhinal Cortex

open access: yesNeural Plasticity, 2008
The entorhinal cortex (EC) is a unique and fascinating structure, constituting a highly parallel interface between phylogenetically old cortex (hippocampus) and higher neocortical areas. The literature related to the EC has increased dramatically in the past 30 years. A simple PubMed search for EC lists around 20–40 articles per year in the early 1980s.
C. Andrew Chapman   +2 more
openaire   +3 more sources

Intrinsic Projections of Layer Vb Neurons to Layers Va, III, and II in the Lateral and Medial Entorhinal Cortex of the Rat

open access: yesCell Reports, 2018
Summary: Layer V of the entorhinal cortex (EC) receives input from the hippocampus and originates main entorhinal outputs. The deep-sublayer Vb, immunopositive for the transcription factor Ctip2, is thought to be the main recipient of hippocampal ...
Shinya Ohara   +7 more
doaj   +1 more source

Entorhinal cortex dysfunction in Alzheimer's disease

open access: yesTrends in Neurosciences, 2023
The entorhinal cortex (EC) is the brain region that often exhibits the earliest histological alterations in Alzheimer's disease (AD), including the formation of neurofibrillary tangles and cell death. Recently, brain imaging studies from preclinical AD patients and electrophysiological recordings from AD animal models have shown that impaired neuronal ...
openaire   +4 more sources

Rat hippocampal CA1 region represents learning-related action and reward events with shorter latency than the lateral entorhinal cortex

open access: yesCommunications Biology, 2023
The hippocampus and entorhinal cortex are deeply involved in learning and memory. However, little is known how ongoing events are processed in the hippocampal-entorhinal circuit.
Shogo Soma   +8 more
doaj   +1 more source

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