Results 101 to 110 of about 50,610 (294)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Numerical Heat Transfer Analysis of Evacuated Tube Solar Collector Using MXene/Soyabean Oil Nanofluid [PDF]

E3S Web of Conferences
This study focuses on investigating the thermo-hydraulic performance and entropy generation rate of an evacuated tube solar collector using MXene/Soybean oil as a working nanofluid by means of Computational Fluid Dynamics (CFD).
Awis Nur Amirah, Ali Syed Awais, Mim Mumtahina, Farabi Sazratul Nayeem, Habib Khairul   +4 more
doaj   +1 more source

Entropy Generation Rates through the Dissipation of Ordered Regions in Helium Boundary-Layer Flows [PDF]

Entropy, 2017
The results of the computation of entropy generation rates through the dissipation of ordered regions within selected helium boundary layer flows are presented. Entropy generation rates in helium boundary layer flows for five cases of increasing temperature and pressure are considered.
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Mixed Convection and Entropy Generation of an Ag-Water Nanofluid in an Inclined L-Shaped Channel

Energies, 2019
This paper investigates the mixed convection and entropy generation of an Ag-water nanofluid in an L-shaped channel fixed at an inclination angle of 30° to the horizontal axis.
Taher Armaghani, Muneer A. Ismael, Ali J. Chamkha, Ioan Pop   +3 more
doaj   +1 more source

Causal Relativistic Fluid Dynamics

, 2011
We derive causal relativistic fluid dynamical equations from the relaxation model of kinetic theory as in a procedure previously applied in the case of non-relativistic rarefied gases.
Chapman S, Chen X, Chen X, E A Spiegel, Israel W, Kolb E W, Landau L D, Liepmann H W, Maartens R, Marle C, Pavon D, Stewart J M, Uhlenbeck G E, Weinberg S, Welander P, X Chen   +15 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Impact of nonlinear thermal radiation for magnetized dissipative flow of ternary hybrid nanomaterial (Al2 O3- SiO2- Fe3 O4- H2 O)

Journal of Radiation Research and Applied Sciences
Present attempt explores convective flow of ternary hybrid nanomaterial by a porous space. Convective condition is imposed. Thermal expression is discussed through non-linear radiation, magnetohydrodynamics, heat source and dissipation.
Aqsa Bashir, Tasawar Hayat, Sohail A. Khan   +2 more
doaj   +1 more source

Entropy Generation in Laminar Fluid Flow through a Circular Pipe

Entropy, 2003
: A numerical solution to the entropy generation in a circular pipe is made. Radial and axial variations are considered. Navier-Stokes equations in cylindrical coordinates are used to solve the velocity and temperature fields.
Rached Ben-Mansour, Ahmet Z. Sahin
doaj   +1 more source