Results 101 to 110 of about 5,740,500 (299)

Entropy Generation Rates through the Dissipation of Ordered Regions in Helium Boundary-Layer Flows [PDF]

Entropy, 2017
The results of the computation of entropy generation rates through the dissipation of ordered regions within selected helium boundary layer flows are presented. Entropy generation rates in helium boundary layer flows for five cases of increasing temperature and pressure are considered.
openaire   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Entropy Generation in Laminar Fluid Flow through a Circular Pipe

Entropy, 2003
: A numerical solution to the entropy generation in a circular pipe is made. Radial and axial variations are considered. Navier-Stokes equations in cylindrical coordinates are used to solve the velocity and temperature fields.
Rached Ben-Mansour, Ahmet Z. Sahin
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Numerical Heat Transfer Analysis of Evacuated Tube Solar Collector Using MXene/Soyabean Oil Nanofluid [PDF]

E3S Web of Conferences
This study focuses on investigating the thermo-hydraulic performance and entropy generation rate of an evacuated tube solar collector using MXene/Soybean oil as a working nanofluid by means of Computational Fluid Dynamics (CFD).
Awis Nur Amirah, Ali Syed Awais, Mim Mumtahina, Farabi Sazratul Nayeem, Habib Khairul   +4 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Minimization of Entropy Generation Rate in Hydrogen Iodide Decomposition Reactor Heated by High-Temperature Helium. [PDF]

Entropy (Basel), 2021
Kong R, Chen L, Xia S, Li P, Ge Y.
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Impact of nonlinear thermal radiation for magnetized dissipative flow of ternary hybrid nanomaterial (Al2 O3- SiO2- Fe3 O4- H2 O)

Journal of Radiation Research and Applied Sciences
Present attempt explores convective flow of ternary hybrid nanomaterial by a porous space. Convective condition is imposed. Thermal expression is discussed through non-linear radiation, magnetohydrodynamics, heat source and dissipation.
Aqsa Bashir, Tasawar Hayat, Sohail A. Khan   +2 more
doaj   +1 more source

Analysis of Entropy Generation Rate During Non-Adiabatic Ice Slurry Flow in Pipes

International Journal of Thermodynamics, 2020
The paper focuses on the entropy generation rate minimization during the flow of ethanol-based ice slurry through straight pipes with a circular and rectangular cross-section. The authors’ original equations for calculating ice slurry flow resistances and heat transfer coefficients were used to determine the impact of the mass fraction of ice, ice ...
openaire   +3 more sources