Results 81 to 90 of about 67,690 (262)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Entropy generation analysis in an evaporative air-cooled heat exchanger

Journal of Thermal Science and Technology, 2014
In the present study, air-side entropy generation rate for an evaporative air-cooled heat exchanger has been investigated using thermodynamic second-law analysis.
Shoeib MAHJOUB, Mohammad Reza SALIMPOUR, Hossein SHOKOUHMAND, Zabihollah BAHRAMI   +3 more
doaj   +1 more source

A generalized quantum relative entropy

Advances in Mathematics of Communications, 2020
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Luiza Helena Félix de Andrade, Rui Facundo Vigelis, Charles C. Cavalcante   +2 more
openaire   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Entropy generation during fluid flow in sharp edge wavy channels with horizontal pitch

Advances in Mechanical Engineering, 2016
In this study, the volumetric entropy generation rate is analyzed in sharp edge wavy channels. A two-dimensional steadily developing fluid flow is considered. Air is considered as the working fluid in the numerical analysis.
Haitham MS Bahaidarah
doaj   +1 more source

Effect of Incidence Angle on Entropy Generation in the Boundary Layers on the Blade Suction Surface in a Compressor Cascade

Entropy, 2019
The entropy generation that occurs within boundary layers over a C4 blade at a Reynolds number of 24,000 and incidence angles (i) of 0°, 2.5°, 5°, 7.5°, and 10° are investigated experimentally using a particle image velocimetry ...
Lei Shi, Hongwei Ma
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Tracing the classical molecular nature of entropy generation

AIP Advances
The second law of thermodynamics and the concept of positive entropy generation are analyzed following classical statistical mechanics methods. Previously, using the generalized Boltzmann–Gibbs entropy and its associated general entropy conservation ...
Michael H. Peters
doaj   +1 more source

Second law efficiency and thermal entropy generation of 30:70% of glycerol + water based SiO2 nanofluids in a thermosyphon flat plate collector: Experimental and Bayesian artificial neural network algorithm

International Journal of Thermofluids
This research examines the thermal entropy generation, frictional entropy generation, entropy generation number, and energy efficiency, which were experimentally assessed for a flat plate collector functioning under thermosyphon conditions utilizing a ...
L.S. Sundar, Sérgio M.O. Tavares, Korada V Sharma, António M.B. Pereira   +3 more
doaj   +1 more source

A mathematical model for entropy generation in a Powell-Eyring nanofluid flow in a porous channel

Heliyon, 2019
The continuous generation of entropy leads to exergy destruction which reduces the performance of a physical system. Hence, entropy minimization becomes necessary.
Hammed Abiodun Ogunseye, Precious Sibanda   +1 more
doaj   +1 more source