Results 101 to 110 of about 3,082,804 (300)

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Entropy generation during fluid flow in sharp edge wavy channels with horizontal pitch

Advances in Mechanical Engineering, 2016
In this study, the volumetric entropy generation rate is analyzed in sharp edge wavy channels. A two-dimensional steadily developing fluid flow is considered. Air is considered as the working fluid in the numerical analysis.
Haitham MS Bahaidarah
doaj   +1 more source

Entropy generation analysis in an evaporative air-cooled heat exchanger

Journal of Thermal Science and Technology, 2014
In the present study, air-side entropy generation rate for an evaporative air-cooled heat exchanger has been investigated using thermodynamic second-law analysis.
Shoeib MAHJOUB, Mohammad Reza SALIMPOUR, Hossein SHOKOUHMAND, Zabihollah BAHRAMI   +3 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Effect of Incidence Angle on Entropy Generation in the Boundary Layers on the Blade Suction Surface in a Compressor Cascade

Entropy, 2019
The entropy generation that occurs within boundary layers over a C4 blade at a Reynolds number of 24,000 and incidence angles (i) of 0°, 2.5°, 5°, 7.5°, and 10° are investigated experimentally using a particle image velocimetry ...
Lei Shi, Hongwei Ma
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Tracing the classical molecular nature of entropy generation

AIP Advances
The second law of thermodynamics and the concept of positive entropy generation are analyzed following classical statistical mechanics methods. Previously, using the generalized Boltzmann–Gibbs entropy and its associated general entropy conservation ...
Michael H. Peters
doaj   +1 more source

Second law efficiency and thermal entropy generation of 30:70% of glycerol + water based SiO2 nanofluids in a thermosyphon flat plate collector: Experimental and Bayesian artificial neural network algorithm

International Journal of Thermofluids
This research examines the thermal entropy generation, frictional entropy generation, entropy generation number, and energy efficiency, which were experimentally assessed for a flat plate collector functioning under thermosyphon conditions utilizing a ...
L.S. Sundar, Sérgio M.O. Tavares, Korada V Sharma, António M.B. Pereira   +3 more
doaj   +1 more source

A mathematical model for entropy generation in a Powell-Eyring nanofluid flow in a porous channel

Heliyon, 2019
The continuous generation of entropy leads to exergy destruction which reduces the performance of a physical system. Hence, entropy minimization becomes necessary.
Hammed Abiodun Ogunseye, Precious Sibanda   +1 more
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source