Results 121 to 130 of about 314,940 (287)

Entropy Generation Analysis for a CNT Suspension Nanofluid in Plumb Ducts with Peristalsis

open access: yesEntropy, 2015
The purpose of the current investigation was to discuss the entropy generation analysis for a carbon nanotube (CNT) suspension nanofluid in a plumb duct with peristalsis. The entropy generation number due to heat transfer and fluid friction is formulated.
Noreen Sher Akbar
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Investigation to define the propagation characteristics of a finite amplitude acoustic pressure wave, phase 1 final report, 29 jun. 1964 - 29 jul. 1965 [PDF]

open access: yes
The contribution of high entropy production regions to the generation and propagation characteristics of a finite amplitude pressure is considered.
Li, T. C., Peter, A. C.
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Optimization of Entropy generation on peristaltic flow of nanofluid having compliant walls by RSM: Sensitivity analysis

open access: yesInternational Journal of Thermofluids
In this study the mathematical model of entropy generation of peristaltic flow of nanofluid is developed under the assumption of long wavelength and low Reynolds number.
Saima Muhammad   +2 more
doaj   +1 more source

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