Results 101 to 110 of about 314,940 (287)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Irreversible thermodynamics of creep in crystalline solids

open access: yes, 2013
We develop an irreversible thermodynamics framework for the description of creep deformation in crystalline solids by mechanisms that involve vacancy diffusion and lattice site generation and annihilation. The material undergoing the creep deformation is
Boettinger, W. J.   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Computations of local nonsimilar solutions for MHD flow of Reiner–Rivlin fluid

open access: yesNonlinear Analysis
Here local nonsimilar solution for hydromagnetic stretched flow of Reiner–Rivlin material is constructed. Heat generation, radiation, and dissipation in thermal expression are studied.
Sohail A. Khan   +3 more
doaj   +1 more source

Entropy generation analysis for non-similar analytical study of nanofluid flow and heat transfer under the influence of aligned magnetic field

open access: yesAlexandria Engineering Journal, 2018
The present semi-analytical investigation covers the impact of aligned magnetic field, Ohmic dissipation and viscous dissipation on a non-similar nanofluid flow over a plate with no flux condition.
Puneet Rana, Nisha Shukla
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Second Law Analysis of AlO-Water Nanofluid Turbulent Forced Convection in a Circular Cross Section Tube with Constant Wall Temperature

open access: yesAdvances in Mechanical Engineering, 2013
The present paper proposes an analysis based on the second principle of thermodynamics applied to a water-Al 2 O 3 nanofluid. The nanofluid flows inside a circular section tube subjected to constant wall temperature.
Vincenzo Bianco   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Chaotic Genetic Algorithm and The Effects of Entropy in Performance Optimization

open access: yes, 2019
This work proposes a new edge about the Chaotic Genetic Algorithm (CGA) and the importance of the entropy in the initial population. Inspired by chaos theory the CGA uses chaotic maps to modify the stochastic parameters of Genetic Algorithm (GA).
Alfaro, Miguel   +5 more
core   +1 more source

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