Results 91 to 100 of about 314,940 (287)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Thermal Analysis in Pipe Flow: Influence of Variable Viscosity on Entropy Generation

Entropy, 2004
: Flow through pipes and heating situations find wide applications in industry. Depending on the fluid properties, temperature field in the pipe changes. This in turn results in thermodynamic irreversibility in the flow system.
Bekir Sami Yilbas, Iyad Talal Al-Zaharnah   +1 more
doaj   +1 more source

Heat transfer and entropy generation analysis of ternary nanofluid

Journal of Computational Design and Engineering
Abstract In light of the rising demand for improved heat transfer in thermal systems, this work offers a unique technique for boosting heat transfer capacity and reducing entropy generation using a ternary nanofluid. Moreover, constant pressure gradient, magnetic field, Joule heating, and thermal radiation also contribute to the flow ...
Ruishi Liang, Hanifa Hanif, Jie Song, S S Alzahrani   +3 more
openaire   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Entropy Generation Analysis for Stagnation Point Flow in a Porous Medium over a Permeable Stretching Surface

Journal of Applied Fluid Mechanics, 2015
This paper presents entropy generation analysis for stagnation point flow in a porous medium over a permeable stretching surface with heat generation/absorption and convective boundary condition.
M. M. Rashidi, F. Mohammadi, S. Abbasbandy, Mohammed S. Alhuthali   +3 more
doaj  

An Evolutionary Approach to the Design of Controllable Cellular Automata Structure for Random Number Generation [PDF]

, 2003
Cellular Automata (CA) has been used in pseudorandom number generation over a decade. Recent studies show that two-dimensional (2-d) CA Pseudorandom Number Generators (PRNGs) may generate better random sequences than conventional one-dimensional (1-d) CA
Guan, SU, Zhang, S
core  

Recommendations and illustrations for the evaluation of photonic random number generators

, 2017
The never-ending quest to improve the security of digital information combined with recent improvements in hardware technology has caused the field of random number generation to undergo a fundamental shift from relying solely on pseudo-random algorithms
Baumgartner, Gerald B., Hart, Joseph D., Murphy, Thomas E., Roy, Rajarshi, Terashima, Yuta, Uchida, Atsushi   +5 more
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Device independent quantum random number generation

, 2018
Randomness is critical for many information processing applications, including numerical modeling and cryptography. Device-independent quantum random number generation (DIQRNG) based on the loophole free violation of Bell inequality produces ...
A Acín, B Hensen, Bing Bai, CA Miller, CA Miller, CE Shannon, Cheng Wu, Hao Li, J Barrett, JF Clauser, Jian-Wei Pan, Jian-Yu Guan, Jingyun Fan, Jun Zhang, Lixing You, LK Shalm, M Giustina, M Herrero-Collantes, MDC Pereira, Ming-Han Li, N Metropolis, P Bierhorst, PB Dixon, PH Eberhard, Qi Zhao, Qiang Zhang, R Bennink, S Pironio, U Vazirani, W Rosenfeld, W Zhang, W. J. Munro, Weijun Zhang, Wen-Zhao Liu, X Ma, Xiao Yuan, Xiongfeng Ma, Y Liu, Y Zhang, Yanbao Zhang, Yang Liu, Zhen Wang   +41 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source