Results 111 to 120 of about 25,153,568 (292)

Entropy generation analysis for non-similar analytical study of nanofluid flow and heat transfer under the influence of aligned magnetic field

open access: yesAlexandria Engineering Journal, 2018
The present semi-analytical investigation covers the impact of aligned magnetic field, Ohmic dissipation and viscous dissipation on a non-similar nanofluid flow over a plate with no flux condition.
Puneet Rana, Nisha Shukla
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Numerical analysis of entropy generation in mixed convection flow with viscous dissipation effects in vertical channel

open access: yes, 2012
[[abstract]]A numerical investigation is performed into the entropy generated within a mixed convection flow with viscous dissipation effects in a parallel-plate vertical channel. In performing the analysis, it is assumed that the flow within the channel
Chen, Cha'o-Kuang; Lai, Hsin-Yi ; Liu, Chin-Chia
core  

Diffuser and Nozzle Design Optimization by Entropy Generation Minimization

open access: yes, 2011
Diffusers and nozzles within a flow system are optimized with respect to their wall shapes for a given change in cross sections. The optimization target is a low value of the head loss coefficient K, which can be linked to the overall entropy generation ...
Heinz Herwig   +3 more
core   +1 more source

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