Results 51 to 60 of about 54,636 (287)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Optimal behavior of viscoelastic flow at resonant frequencies

open access: yes, 2004
The global entropy generation rate in the zero-mean oscillatory flow of a Maxwell fluid in a pipe is analyzed with the aim at determining its behavior at resonant flow conditions.
A. A. Lambert   +15 more
core   +1 more source

Determining the Optimum Inner Diameter of Condenser Tubes Based on Thermodynamic Objective Functions and an Economic Analysis

open access: yesEntropy, 2016
The diameter and configuration of tubes are important design parameters of power condensers. If a proper tube diameter is applied during the design of a power unit, a high energy efficiency of the condenser itself can be achieved and the performance of ...
Rafał Laskowski   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

a variational approach to niche construction [PDF]

open access: yes, 2018
In evolutionary biology, niche construction is sometimes described as a genuine evolutionary process whereby organisms, through their activities and regulatory mechanisms, modify their environment such as to steer their own evolutionary trajectory, and ...
Campbell, John   +4 more
core   +2 more sources

Minimal entropy conditions for scalar conservation laws with general convex fluxes

open access: yesQuarterly of Applied Mathematics, 2023
We are concerned with the minimal entropy conditions for one-dimensional scalar conservation laws with general convex flux functions. For such scalar conservation laws, we prove that a single entropy-entropy flux pair ( η ( u ) , q ( u ) ) (\eta (u),q(u)) with
Cao, G, Chen, G-QG
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

H2B: Heartbeat-based Secret Key Generation Using Piezo Vibration Sensors

open access: yes, 2019
We present Heartbeats-2-Bits (H2B), which is a system for securely pairing wearable devices by generating a shared secret key from the skin vibrations caused by heartbeat. This work is motivated by potential power saving opportunity arising from the fact
Hassan, Mahbub   +6 more
core   +1 more source

Optimal Design of Isothermal Sloshing Vessels by Entropy Generation Minimization Method

open access: yesMathematics, 2019
In this manuscript, the optimal design of geometry for a forced sloshing in a rigid container based on the entropy generation minimization (EGM) method is presented.
Mohammad Yaghoub Abdollahzadeh Jamalabadi
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

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